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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 69 documents. Results 1 - 10.

Drosophila melanogaster
Gene: ... High impact information on Mekk1 The MAPKKK Mekk1 regulates the expression of Turandot stress genes in response to septic injury in Drosophila. Interestingly, Mekk1 flies are resistant to microbial infection... consequences of mutations in three of the genes, Slpr( dMLK ), Tak1, and Mekk1. Other interactions of Mekk1 Our... / Synonyms: D-MEKK1; D-Mekk1; DmMEKK1
Arabidopsis thaliana
Gene: ... High impact information on MEKK1 In Arabidopsis protoplasts, MKK2 was specifically activated by cold and salt stress and by the stress- induced MAPK kinase kinase MEKK1. MEKK1 Is Required for MPK4... that MEKK1 is not required for flagellin- triggered activation of MPK3 and MPK6. These results suggest...
Homo sapiens
Gene: ... Disease relevance of MAP3K1 MEKK1 induced AR- dependent apoptosis in prostate cancer cells..., and this event is abolished by pertussis toxin, dominant negative H- Ras, or dominant negative MEKK1. Dominant negative MEKK1 inhibits survival of pancreatic cancer cells. HTLV- I Tax protein binds to MEKK1... / Synonyms: MEKK 1; MEKK1
Mus musculus
Gene: ... hypertrophy and expression of atrial natriuretic factor in Mekk1 (-/-) animals, which showed higher mortality... as a potential mediator of TGF- beta signal transduction. Our data emphasize that MEKK1 is an essential component... production. Mice lacking activity of the kinase MEKK1 (' Map3k1( DeltaKD )' mice) have defective activation... / Synonyms: MEKK 1; MEKK1; Mekk1
Mus musculus
Gene: ... . Activation of stress- activated protein kinase by MEKK1 phosphorylation of its activator SEK1. Here we report.... Selective induction of caspase- dependent MEK cleavage and up- regulation of MEKK- 1. Inhibiting T cell ERK... during placentogenesis. Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined... / Synonyms: MEKK1
MeSH term: ... and expression of atrial natriuretic factor in Mekk1 (-/-) animals, which showed higher mortality and lung/ body..., MEKK1 appears to be required for pressure overload- induced JNK activation and cytokine upregulation.... The MEKK1- JNK pathway plays a protective role in pressure overload but does not mediate cardiac...
Rattus norvegicus
Gene: ... MAPKKK activity. Expression of the constitutively active form of either MEKK1 or MEKK4 mimicked... is triggered when c- Jun is co- expressed with activated MEKK1 or SEK1. Endogenous and recombinant rat MEKK1... PKCs are activated, and PKCbeta regulates phosphorylation of serine in MEKK1. Insulin activates a novel... / Synonyms: MEKK 1; Mekk1
MeSH term: ... with an inability of IB1 to prevent apoptosis induced by MAPK/ ERK kinase kinase 1( MEKK1) and a reduced ability..., and programmed cell death. All apoptosis signaling pathways converge on a common machinery of cell destruction...
Homo sapiens
Gene: ... . MEKK1 binds raf- 1 and the ERK2 cascade components. Pyst2 binds p42 MAP kinase in vivo and both MAP..., and responses to stress stimuli such as osmolarity changes. In this review, we define all known MAPK module...
MeSH term: ... mitotic checkpoint MAD1 protein. HTLV- I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity...

 

 
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