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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Article

BCAC (Breast Cancer Association Consortium)

 
 

Investigators conducting association studies in breast cancer. Supported by grants from Cancer Research UK and the European Union Framework 7 Programme.

 

Website

 

 

Principal investigator or primary contact

Douglas Easton

 

Primary phenotype

Breast cancer

 

Secondary phenotype(s)

Breast cancer subtypes, breast cancer survival

 

Number of GWAS Studies Contributing to the Consortium

69

 

Approx. total number of subjects

200000

 

GWAS data available

yes

 

Key References and Articles

[1]

[2]

 

References

  1. Genome-wide association analysis identifies three new breast cancer susceptibility loci. Ghoussaini, M., Fletcher, O., Michailidou, K., Turnbull, C., Schmidt, M.K., Dicks, E., Dennis, J., Wang, Q., Humphreys, M.K., Luccarini, C., Baynes, C., Conroy, D., Maranian, M., Ahmed, S., Driver, K., Johnson, N., Orr, N., Dos Santos Silva, I., Waisfisz, Q., Meijers-Heijboer, H., Uitterlinden, A.G., Rivadeneira, F., Hall, P., Czene, K., Irwanto, A., Liu, J., Nevanlinna, H., Aittomäki, K., Blomqvist, C., Meindl, A., Schmutzler, R.K., Müller-Myhsok, B., Lichtner, P., Chang-Claude, J., Hein, R., Nickels, S., Flesch-Janys, D., Tsimiklis, H., Makalic, E., Schmidt, D., Bui, M., Hopper, J.L., Apicella, C., Park, D.J., Southey, M., Hunter, D.J., Chanock, S.J., Broeks, A., Verhoef, S., Hogervorst, F.B., Fasching, P.A., Lux, M.P., Beckmann, M.W., Ekici, A.B., Sawyer, E., Tomlinson, I., Kerin, M., Marme, F., Schneeweiss, A., Sohn, C., Burwinkel, B., Guénel, P., Truong, T., Cordina-Duverger, E., Menegaux, F., Bojesen, S.E., Nordestgaard, B.G., Nielsen, S.F., Flyger, H., Milne, R.L., Alonso, M.R., González-Neira, A., Benítez, J., Anton-Culver, H., Ziogas, A., Bernstein, L., Dur, C.C., Brenner, H., Müller, H., Arndt, V., Stegmaier, C., Justenhoven, C., Brauch, H., Brüning, T., Wang-Gohrke, S., Eilber, U., Dörk, T., Schürmann, P., Bremer, M., Hillemanns, P., Bogdanova, N.V., Antonenkova, N.N., Rogov, Y.I., Karstens, J.H., Bermisheva, M., Prokofieva, D., Khusnutdinova, E., Lindblom, A., Margolin, S., Mannermaa, A., Kataja, V., Kosma, V.M., Hartikainen, J.M., Lambrechts, D., Yesilyurt, B.T., Floris, G., Leunen, K., Manoukian, S., Bonanni, B., Fortuzzi, S., Peterlongo, P., Couch, F.J., Wang, X., Stevens, K., Lee, A., Giles, G.G., Baglietto, L., Severi, G., McLean, C., Alnæs, G.G., Kristensen, V., Børrensen-Dale, A.L., John, E.M., Miron, A., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Kauppila, S., Andrulis, I.L., Glendon, G., Mulligan, A.M., Devilee, P., van Asperen, C.J., Tollenaar, R.A., Seynaeve, C., Figueroa, J.D., Garcia-Closas, M., Brinton, L., Lissowska, J., Hooning, M.J., Hollestelle, A., Oldenburg, R.A., van den Ouweland, A.M., Cox, A., Reed, M.W., Shah, M., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Jones, M., Schoemaker, M., Ashworth, A., Swerdlow, A., Beesley, J., Chen, X., Muir, K.R., Lophatananon, A., Rattanamongkongul, S., Chaiwerawattana, A., Kang, D., Yoo, K.Y., Noh, D.Y., Shen, C.Y., Yu, J.C., Wu, P.E., Hsiung, C.N., Perkins, A., Swann, R., Velentzis, L., Eccles, D.M., Tapper, W.J., Gerty, S.M., Graham, N.J., Ponder, B.A., Chenevix-Trench, G., Pharoah, P.D., Lathrop, M., Dunning, A.M., Rahman, N., Peto, J., Easton, D.F. Nat. Genet. (2012) [Pubmed]
  2. Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium. Broeks, A., Schmidt, M.K., Sherman, M.E., Couch, F.J., Hopper, J.L., Dite, G.S., Apicella, C., Smith, L.D., Hammet, F., Southey, M.C., Van 't Veer, L.J., de Groot, R., Smit, V.T., Fasching, P.A., Beckmann, M.W., Jud, S., Ekici, A.B., Hartmann, A., Hein, A., Schulz-Wendtland, R., Burwinkel, B., Marme, F., Schneeweiss, A., Sinn, H.P., Sohn, C., Tchatchou, S., Bojesen, S.E., Nordestgaard, B.G., Flyger, H., Ørsted, D.D., Kaur-Knudsen, D., Milne, R.L., Pérez, J.I., Zamora, P., Rodríguez, P.M., Benítez, J., Brauch, H., Justenhoven, C., Ko, Y.D., Hamann, U., Fischer, H.P., Brüning, T., Pesch, B., Chang-Claude, J., Wang-Gohrke, S., Bremer, M., Karstens, J.H., Hillemanns, P., Dörk, T., Nevanlinna, H.A., Heikkinen, T., Heikkilä, P., Blomqvist, C., Aittomäki, K., Aaltonen, K., Lindblom, A., Margolin, S., Mannermaa, A., Kosma, V.M., Kauppinen, J.M., Kataja, V., Auvinen, P., Eskelinen, M., Soini, Y., Chenevix-Trench, G., Spurdle, A.B., Beesley, J., Chen, X., Holland, H., Lambrechts, D., Claes, B., Vandorpe, T., Neven, P., Wildiers, H., Flesch-Janys, D., Hein, R., Löning, T., Kosel, M., Fredericksen, Z.S., Wang, X., Giles, G.G., Baglietto, L., Severi, G., McLean, C., Haiman, C.A., Henderson, B.E., Le Marchand, L., Kolonel, L.N., Alnæs, G.G., Kristensen, V., Børresen-Dale, A.L., Hunter, D.J., Hankinson, S.E., Andrulis, I.L., Mulligan, A.M., O'Malley, F.P., Devilee, P., Huijts, P.E., Tollenaar, R.A., Van Asperen, C.J., Seynaeve, C.S., Chanock, S.J., Lissowska, J., Brinton, L., Peplonska, B., Figueroa, J., Yang, X.R., Hooning, M.J., Hollestelle, A., Oldenburg, R.A., Jager, A., Kriege, M., Ozturk, B., van Leenders, G.J., Hall, P., Czene, K., Humphreys, K., Liu, J., Cox, A., Connley, D., Cramp, H.E., Cross, S.S., Balasubramanian, S.P., Reed, M.W., Dunning, A.M., Easton, D.F., Humphreys, M.K., Caldas, C., Blows, F., Driver, K., Provenzano, E., Lubinski, J., Jakubowska, A., Huzarski, T., Byrski, T., Cybulski, C., Gorski, B., Gronwald, J., Brennan, P., Sangrajrang, S., Gaborieau, V., Shen, C.Y., Hsiung, C.N., Yu, J.C., Chen, S.T., Hsu, G.C., Hou, M.F., Huang, C.S., Anton-Culver, H., Ziogas, A., Pharoah, P.D., Garcia-Closas, M. Hum. Mol. Genet. (2011) [Pubmed]
 
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