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Sam Gandy

Farber Institute for Neurosciences and the Department of Neurology

Thomas Jefferson University

Philadelphia

Pennsylvania

USA

[email]@earthlink.net

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Farber Institute for Neurosciences and the Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. 2002 - 2007
  • Sir James McCusker Alzheimer Research Unit, University of Western Australia, Perth, Australia and Department of Psychiatry, USA. 2001

References

  1. Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo. Gandy, S., Zhang, Y.W., Ikin, A., Schmidt, S.D., Bogush, A., Levy, E., Sheffield, R., Nixon, R.A., Liao, F.F., Mathews, P.M., Xu, H., Ehrlich, M.E. J. Neurochem. (2007) [Pubmed]
  2. Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding. Ikin, A.F., Causevic, M., Pedrini, S., Benson, L.S., Buxbaum, J.D., Suzuki, T., Lovestone, S., Higashiyama, S., Mustelin, T., Burgoyne, R.D., Gandy, S. Mol. Neurodegener (2007) [Pubmed]
  3. The role of cerebral amyloid beta accumulation in common forms of Alzheimer disease. Gandy, S. J. Clin. Invest. (2005) [Pubmed]
  4. Breaking up (amyloid) is hard to do. Gandy, S., Heppner, F.L. PLoS Med. (2005) [Pubmed]
  5. Alzheimer's Abeta vaccination of rhesus monkeys (Macaca mulatta). Gandy, S., DeMattos, R.B., Lemere, C.A., Heppner, F.L., Leverone, J., Aguzzi, A., Ershler, W.B., Dai, J., Fraser, P., St George Hyslop, P., Holtzman, D.M., Walker, L.C., Keller, E.T. Mech. Ageing Dev. (2004) [Pubmed]
  6. Alzheimer A beta vaccination of rhesus monkeys (Macaca mulatta). Gandy, S., DeMattos, R.B., Lemere, C.A., Heppner, F.L., Leverone, J., Aguzzi, A., Ershler, W.B., Dai, J., Fraser, P., Hyslop, P.S., Holtzman, D.M., Walker, L.C., Keller, E.T. Alzheimer. Dis. Assoc. Disord (2004) [Pubmed]
  7. Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding. Parvathy, S., Ehrlich, M., Pedrini, S., Diaz, N., Refolo, L., Buxbaum, J.D., Bogush, A., Petanceska, S., Gandy, S. J. Neurochem. (2004) [Pubmed]
  8. Toward modeling hemorrhagic and encephalitic complications of Alzheimer amyloid-beta vaccination in nonhuman primates. Gandy, S., Walker, L. Curr. Opin. Immunol. (2004) [Pubmed]
  9. Molecular and cellular basis for anti-amyloid therapy in Alzheimer disease. Gandy, S., Martins, R.N., Buxbaum, J. Alzheimer. Dis. Assoc. Disord (2003) [Pubmed]
  10. Molecular basis for anti-amyloid therapy in the prevention and treatment of Alzheimer's disease. Gandy, S. Neurobiol. Aging (2002) [Pubmed]
  11. Alzheimer's disease. Molecular consequences of presenilin-1 mutation. Gandy, S., Naslund, J., Nordstedt, C. Nature (2001) [Pubmed]
 
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