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F. Peter Guengerich
Department of Biochemistry and Center in Molecular Toxicology
Vanderbilt University School of Medicine
638 Robinson Research Building
2200 Pierce Avenue
Name/email consistency: high
- Orphans in the human cytochrome p450 superfamily: approaches to discovering functions and relevance in pharmacology. Guengerich, F.P., Cheng, Q. Pharmacol. Rev. (2011)
- Cytochrome P450 2S1 is Reduced by NADPH-Cytochrome P450 Reductase. Xiao, Y., Shinkyo, R., Guengerich, F.P. Drug Metab. Dispos. (2011)
- Approaches to deorphanization of human and microbial cytochrome P450 enzymes. Guengerich, F.P., Tang, Z., Cheng, Q., Salamanca-Pinzón, S.G. Biochim. Biophys. Acta (2011)
- Multi-step oxidations catalyzed by cytochrome P450 enzymes: Processive vs. distributive kinetics and the issue of carbonyl oxidation in chemical mechanisms. Guengerich, F.P., Sohl, C.D., Chowdhury, G. Arch. Biochem. Biophys. (2011)
- Update information on drug metabolism systems--2009, part I. Guengerich, F.P., Rendic, S. Curr. Drug Metab. (2010)
- Measurement of cytochrome P450 and NADPH-cytochrome P450 reductase. Guengerich, F.P., Martin, M.V., Sohl, C.D., Cheng, Q. Nat. Protoc (2009)
- Thematic series: metals in biology. Guengerich, F.P. J. Biol. Chem. (2009)
- Thematic minireview series: metals in biology. Guengerich, F.P. J. Biol. Chem. (2009)
- Cytochrome p450 and chemical toxicology. Guengerich, F.P. Chem. Res. Toxicol. (2008)
- Mechanisms of cytochrome P450 substrate oxidation: MiniReview. Guengerich, F.P. J. Biochem. Mol. Toxicol. (2007)
- Applying mechanisms of chemical toxicity to predict drug safety. Guengerich, F.P., MacDonald, J.S. Chem. Res. Toxicol. (2007)
- Interactions of carcinogen-bound DNA with individual DNA polymerases. Guengerich, F.P. Chem. Rev. (2006)
- Cytochrome P450s and other enzymes in drug metabolism and toxicity. Guengerich, F.P. AAPS. J (2006)
- A malleable catalyst dominates the metabolism of drugs. Guengerich, F.P. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Principles of covalent binding of reactive metabolites and examples of activation of bis-electrophiles by conjugation. Guengerich, F.P. Arch. Biochem. Biophys. (2005)
- Generation of reactive intermediates. Guengerich, F.P. J. Biochem. Mol. Toxicol. (2005)
- Life and times in biochemical toxicology. Guengerich, F.P. Int. J. Toxicol. (2005)
- Reduction of cytochrome b5 by NADPH-cytochrome P450 reductase. Guengerich, F.P. Arch. Biochem. Biophys. (2005)
- Function of human cytochrome P450s: characterization of the orphans. Guengerich, F.P., Wu, Z.L., Bartleson, C.J. Biochem. Biophys. Res. Commun. (2005)
- Generation of new protein kinase inhibitors utilizing cytochrome p450 mutant enzymes for indigoid synthesis. Guengerich, F.P., Sorrells, J.L., Schmitt, S., Krauser, J.A., Aryal, P., Meijer, L. J. Med. Chem. (2004)
- Cytochrome P450: what have we learned and what are the future issues?. Guengerich, F.P. Drug Metab. Rev. (2004)
- Rate-limiting steps in oxidations catalyzed by rabbit cytochrome P450 1A2. Guengerich, F.P., Krauser, J.A., Johnson, W.W. Biochemistry (2004)
- Where is toxicology headed in the future?. Guengerich, F.P. Drug Metab. Rev. (2004)
- O6-alkylguanine-DNA alkyltransferase: low pKa and high reactivity of cysteine 145. Guengerich, F.P., Fang, Q., Liu, L., Hachey, D.L., Pegg, A.E. Biochemistry (2003)
- Cytochromes P450, drugs, and diseases. Guengerich, F.P. Mol. Interv. (2003)
