Richard S. Hotchkiss
Department of Anesthesiology
Howard Hughes Medical Institute
Washington University School of Medicine
St. Louis
USA
Name/email consistency: high
- The pathophysiology and treatment of sepsis. Hotchkiss, R.S., Karl, I.E. N. Engl. J. Med. (2003)
- Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis. Hotchkiss, R.S., Chang, K.C., Grayson, M.H., Tinsley, K.W., Dunne, B.S., Davis, C.G., Osborne, D.F., Karl, I.E. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Role of apoptotic cell death in sepsis. Hotchkiss, R.S., Tinsley, K.W., Karl, I.E. Scand. J. Infect. Dis. (2003)
- Depletion of dendritic cells, but not macrophages, in patients with sepsis. Hotchkiss, R.S., Tinsley, K.W., Swanson, P.E., Grayson, M.H., Osborne, D.F., Wagner, T.H., Cobb, J.P., Coopersmith, C., Karl, I.E. J. Immunol. (2002)
- Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans. Hotchkiss, R.S., Tinsley, K.W., Swanson, P.E., Schmieg, R.E., Hui, J.J., Chang, K.C., Osborne, D.F., Freeman, B.D., Cobb, J.P., Buchman, T.G., Karl, I.E. J. Immunol. (2001)
- Role of apoptosis in Pseudomonas aeruginosa pneumonia. Hotchkiss, R.S., Dunne, W.M., Swanson, P.E., Davis, C.G., Tinsley, K.W., Chang, K.C., Buchman, T.G., Karl, I.E. Science (2001)
- p53-dependent and -independent pathways of apoptotic cell death in sepsis. Hotchkiss, R.S., Tinsley, K.W., Hui, J.J., Chang, K.C., Swanson, P.E., Drewry, A.M., Buchman, T.G., Karl, I.E. J. Immunol. (2000)
- Rapid onset of intestinal epithelial and lymphocyte apoptotic cell death in patients with trauma and shock. Hotchkiss, R.S., Schmieg, R.E., Swanson, P.E., Freeman, B.D., Tinsley, K.W., Cobb, J.P., Karl, I.E., Buchman, T.G. Crit. Care Med. (2000)
- Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte. Hotchkiss, R.S., Chang, K.C., Swanson, P.E., Tinsley, K.W., Hui, J.J., Klender, P., Xanthoudakis, S., Roy, S., Black, C., Grimm, E., Aspiotis, R., Han, Y., Nicholson, D.W., Karl, I.E. Nat. Immunol. (2000)
- Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis. Hotchkiss, R.S., Swanson, P.E., Knudson, C.M., Chang, K.C., Cobb, J.P., Osborne, D.F., Zollner, K.M., Buchman, T.G., Korsmeyer, S.J., Karl, I.E. J. Immunol. (1999)
- Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction. Hotchkiss, R.S., Swanson, P.E., Freeman, B.D., Tinsley, K.W., Cobb, J.P., Matuschak, G.M., Buchman, T.G., Karl, I.E. Crit. Care Med. (1999)
- Prevention of lymphocyte cell death in sepsis improves survival in mice. Hotchkiss, R.S., Tinsley, K.W., Swanson, P.E., Chang, K.C., Cobb, J.P., Buchman, T.G., Korsmeyer, S.J., Karl, I.E. Proc. Natl. Acad. Sci. U.S.A. (1999)