J.D. Sandy
Shriners Hospital for Children
Tampa
Florida 33612
USA
Name/email consistency: high
- Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4. Sandy, J.D., Westling, J., Kenagy, R.D., Iruela-Arispe, M.L., Verscharen, C., Rodriguez-Mazaneque, J.C., Zimmermann, D.R., Lemire, J.M., Fischer, J.W., Wight, T.N., Clowes, A.W. J. Biol. Chem. (2001)
- Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing in vivo. Sandy, J.D., Verscharen, C. Biochem. J. (2001)
- The intermediates of aggrecanase-dependent cleavage of aggrecan in rat chondrosarcoma cells treated with interleukin-1. Sandy, J.D., Thompson, V., Doege, K., Verscharen, C. Biochem. J. (2000)
- Chondrocyte-mediated catabolism of aggrecan: evidence for a glycosylphosphatidylinositol-linked protein in the aggrecanase response to interleukin-1 or retinoic acid. Sandy, J.D., Thompson, V., Verscharen, C., Gamett, D. Arch. Biochem. Biophys. (1999)