The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

Chenodiol     (4R)-4-[ (3R,5S,7R,8S,9S,10S,13R,14S,17 R)-3...

Synonyms: Chenofalk, Henohol, Chenix, Chenique Acid, Chenic acid, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of Chenodiol

 

Psychiatry related information on Chenodiol

 

High impact information on Chenodiol

 

Chemical compound and disease context of Chenodiol

 

Biological context of Chenodiol

 

Anatomical context of Chenodiol

 

Associations of Chenodiol with other chemical compounds

 

Gene context of Chenodiol

 

Analytical, diagnostic and therapeutic context of Chenodiol

References

  1. Chenodeoxycholic acid treatment of gallstones. A follow-up report and analysis of factors influencing response to therapy. Iser, J.H., Dowling, H., Mok, H.Y., Bell, G.D. N. Engl. J. Med. (1975) [Pubmed]
  2. Long-term treatment of cerebrotendinous xanthomatosis with chenodeoxycholic acid. Berginer, V.M., Salen, G., Shefer, S. N. Engl. J. Med. (1984) [Pubmed]
  3. Chenodeoxycholic acid in the prevention of migraine. Lévy, V.G., Nusinovici, V., Rosner, D., Darnis, F. N. Engl. J. Med. (1978) [Pubmed]
  4. Hepatic and extrahepatic glucuronidation of bile acids in man. Characterization of bile acid uridine 5'-diphosphate-glucuronosyltransferase in hepatic, renal, and intestinal microsomes. Matern, S., Matern, H., Farthmann, E.H., Gerok, W. J. Clin. Invest. (1984) [Pubmed]
  5. Chenotherapy for gallstone dissolution. II. Induced changes in bile composition and gallstone response. Hofmann, A.F., Thistle, J.L., Klein, P.D., Szczepanik, P.A., Yu, P.Y. JAMA (1978) [Pubmed]
  6. Strain differences in purified rat hepatic 3 alpha-hydroxysteroid UDP-glucuronosyltransferase. Green, M.D., Falany, C.N., Kirkpatrick, R.B., Tephly, T.R. Biochem. J. (1985) [Pubmed]
  7. The proximal colonic motor response to rectal mechanical and chemical stimulation. Bampton, P.A., Dinning, P.G., Kennedy, M.L., Lubowski, D.Z., Cook, I.J. Am. J. Physiol. Gastrointest. Liver Physiol. (2002) [Pubmed]
  8. Effects of bile salts on the motor activity of the guinea-pig gall-bladder in vitro. Rutishauser, S.C. Quarterly journal of experimental physiology and cognate medical sciences. (1978) [Pubmed]
  9. Increased concentrations of cholestanol and apolipoprotein B in the cerebrospinal fluid of patients with cerebrotendinous xanthomatosis. Effect of chenodeoxycholic acid. Salen, G., Berginer, V., Shore, V., Horak, I., Horak, E., Tint, G.S., Shefer, S. N. Engl. J. Med. (1987) [Pubmed]
  10. Treatment of gallstones with chenodeoxycholic acid and phenobarbital. Coyne, M.J., Bonorris, G.G., Chung, A., Goldstein, L.I., Lahana, D., Schoenfield, L.J. N. Engl. J. Med. (1975) [Pubmed]
  11. Effect of chenodiol on the small intestine. Unimpaired structure and function during therapy for gallstone dissolution. Casanova, S., Roda, A., Festi, D., Mazzella, G., Aldini, R., Bazzoli, F., Sama, C., Morselli, A.M., Barbara, L., Roda, E. JAMA (1981) [Pubmed]
  12. Chenotherapy for gallstone dissolution. I. Efficacy and safety. Thistle, J.L., Hofmann, A.F., Ott, B.J., Stephens, D.H. JAMA (1978) [Pubmed]
  13. Biosynthesis of bile acids in cerebrotendinous xanthomatosis. Relationship of bile acid pool sizes and synthesis rates to hydroxylations at C-12, C-25, and C-26. Salen, G., Shefer, S., Tint, G.S., Nicolau, G., Dayal, B., Batta, A.K. J. Clin. Invest. (1985) [Pubmed]
  14. Comparative efficacy and side effects of ursodeoxycholic and chenodeoxycholic acids in dissolving gallstones. A double-blind controlled study. Fromm, H., Roat, J.W., Gonzalez, V., Sarva, R.P., Farivar, S. Gastroenterology (1983) [Pubmed]
  15. Impaired lithocholate sulfation in the rhesus monkey: a possible mechanism for chenodeoxycholate toxicity. Gadacz, T.R., Allan, R.N., Mack, E., Hofmann, A.F. Gastroenterology (1976) [Pubmed]
  16. Transformation of chenodeoxycholic acid to ursodeoxycholic acid in patients with Crohn's disease. Miwa, H., Yamamoto, M., Nishida, T., Yao, T. Gastroenterology (1986) [Pubmed]
  17. Effects of cholecystectomy on the kinetics of primary and secondary bile acids. Berr, F., Stellaard, F., Pratschke, E., Paumgartner, G. J. Clin. Invest. (1989) [Pubmed]
  18. Chronic ursodeoxycholic acid- and chenodeoxycholic acid-feeding-induced changes of colon mucosal cell proliferation in rats. Simanowski, U.A., Seitz, H.K., Czygan, P., Hörner, M., Waldherr, R., Weber, E., Kommerell, B. J. Natl. Cancer Inst. (1987) [Pubmed]
  19. Acute effects of ursodeoxycholic and chenodeoxycholic acid on the small intestinal absorption of bile acids. Stiehl, A., Raedsch, R., Rudolph, G. Gastroenterology (1990) [Pubmed]
  20. Effects of low dose chenodeoxycholic acid feeding on biliary lipid metabolism. Adler, R.D., Bennion, L.J., Duane, W.C., Grundy, S.M. Gastroenterology (1975) [Pubmed]
  21. Ursodeoxycholic acid, 7-ketolithocholic acid, and chenodeoxycholic acid are primary bile acids of the nutria (Myocastor coypus). Tint, G.S., Bullock, J., Batta, A.K., Shefer, S., Salen, G. Gastroenterology (1986) [Pubmed]
  22. A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR. Downes, M., Verdecia, M.A., Roecker, A.J., Hughes, R., Hogenesch, J.B., Kast-Woelbern, H.R., Bowman, M.E., Ferrer, J.L., Anisfeld, A.M., Edwards, P.A., Rosenfeld, J.M., Alvarez, J.G., Noel, J.P., Nicolaou, K.C., Evans, R.M. Mol. Cell (2003) [Pubmed]
  23. Bile acid synthesis by long-term cultured cell line established from human hepatoblastoma. Amuro, Y., Tanaka, M., Higashino, K., Hayashi, E., Endo, T., Kishimoto, S., Nakabayashi, H., Sato, J. J. Clin. Invest. (1982) [Pubmed]
  24. In vivo and vitro studies on formation of bile acids in patients with Zellweger syndrome. Evidence that peroxisomes are of importance in the normal biosynthesis of both cholic and chenodeoxycholic acid. Kase, B.F., Pedersen, J.I., Strandvik, B., Björkhem, I. J. Clin. Invest. (1985) [Pubmed]
  25. Mast cells and histamine contribute to bile acid-stimulated secretion in the mouse colon. Gelbmann, C.M., Schteingart, C.D., Thompson, S.M., Hofmann, A.F., Barrett, K.E. J. Clin. Invest. (1995) [Pubmed]
  26. Role of activation of protein kinase C in the stimulation of colonic epithelial proliferation and reactive oxygen formation by bile acids. Craven, P.A., Pfanstiel, J., DeRubertis, F.R. J. Clin. Invest. (1987) [Pubmed]
  27. Bile salt stimulation of colonic epithelial proliferation. Evidence for involvement of lipoxygenase products. DeRubertis, F.R., Craven, P.A., Saito, R. J. Clin. Invest. (1984) [Pubmed]
  28. Physicochemical and physiological properties of cholylsarcosine. A potential replacement detergent for bile acid deficiency states in the small intestine. Lillienau, J., Schteingart, C.D., Hofmann, A.F. J. Clin. Invest. (1992) [Pubmed]
  29. Differing effects of nor-ursodeoxycholic or ursodeoxycholic acid on hepatic histology and bile acid metabolism in the rabbit. Cohen, B.I., Hofmann, A.F., Mosbach, E.H., Stenger, R.J., Rothschild, M.A., Hagey, L.R., Yoon, Y.B. Gastroenterology (1986) [Pubmed]
  30. Colonic luminal contents induce cyclooxygenase 2 transcription in human colon carcinoma cells. Glinghammar, B., Rafter, J. Gastroenterology (2001) [Pubmed]
  31. FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity. Barbier, O., Torra, I.P., Sirvent, A., Claudel, T., Blanquart, C., Duran-Sandoval, D., Kuipers, F., Kosykh, V., Fruchart, J.C., Staels, B. Gastroenterology (2003) [Pubmed]
  32. Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells. Li, T., Jahan, A., Chiang, J.Y. Hepatology (2006) [Pubmed]
  33. VPAC1 expression is regulated by FXR agonists in the human gallbladder epithelium. Chignard, N., Mergey, M., Barbu, V., Finzi, L., Tiret, E., Paul, A., Housset, C. Hepatology (2005) [Pubmed]
  34. Bile acids with differing hydrophilic-hydrophobic properties do not influence cytokine production by human monocytes and murine Kupffer cells. Bergamini, A., Dini, L., Baiocchi, L., Cappannoli, L., Falasca, L., Bolacchi, F., Capozzi, M., Faggioli, E., Nistri, A., Salanitro, A., Ventura, L., Rocchi, G., Angelico, M. Hepatology (1997) [Pubmed]
  35. Radioimmunoassay of bile acids: development, validation, and preliminary application of an assay for conjugates of chenodeoxycholic acid. Schalm, S.W., van Berge-Henegouwen, G.P., Hofmann, A.F., Cowen, A.E., Turcotte, J. Gastroenterology (1977) [Pubmed]
  36. Serum primary bile acids in Gilbert's syndrome. Roda, A., Roda, E., Sama, C., Festi, D., Aldini, R., Morselli, A.M., Mazzella, G., Barbara, L. Gastroenterology (1982) [Pubmed]
  37. Individual bile acids in portal venous and systemic blood serum of fasting man. Ahlberg, J., Angelin, B., Björkhem, I., Einarsson, K. Gastroenterology (1977) [Pubmed]
  38. Bile acids modify alkaline phosphatase induction and bile secretion pressure after bile duct obstruction in the rat. Hatoff, D.E., Hardison, W.G. Gastroenterology (1981) [Pubmed]
 
WikiGenes - Universities