Chemical Compound Review:
Peroxonitrite oxido nitrite
Synonyms:
Pernitrite, azoperoxoite, Peroxynitrate, Peroxynitrite, ONOO-, ...
Koprowski,
Zingarelli,
Cross,
Beckman,
Schulz,
Umezawa,
Orabona,
Liaudet,
Dickson,
Freeman,
Szabó,
Campbell,
Shelanski,
Nossuli,
Joseph Rabani,
Hery,
Ying,
Szabó,
Grayson,
Jones,
Okada,
Satterlee,
Puccetti,
Brown,
Tanaka,
Schöneich,
Sharov,
Estévez,
Barbeito,
Cohen,
Pacher,
Weisbrod,
Nakazawa,
Beckman,
Rabacchi,
Zou,
Portegies,
Cuzzocrea,
Eiserich,
Sara Goldstein,
Fioretti,
Hooper,
O'Connor,
Lefer,
Gray,
Kean,
Grohmann,
Halliwell,
Verhoef,
Salamon,
Bianchi,
Crow,
Chaudhry,
Vacca,
Hristova,
Frappier,
van der Vliet,
Salzman,
Nottet,
Daniela Salvemini,
William L. Neumann,
Pimentel,
Boven,
Spitsin,
Scalia,
Bachschmid,
Adachi,
Lefer,
Koga,
Fallarino,
Pacher,
Friedman,
Troy,
Fukuyama,
Liaudet,
Hayward,
Champion,
Gomes,
Tardieu,
Pall,
- Nitric oxide and peroxynitrite in health and disease. Pacher, P., Beckman, J.S., Liaudet, L. Physiol. Rev. (2007)
- Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Eiserich, J.P., Hristova, M., Cross, C.E., Jones, A.D., Freeman, B.A., Halliwell, B., van der Vliet, A. Nature (1998)
- Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. Cuzzocrea, S., Riley, D.P., Caputi, A.P., Salvemini, D. Pharmacol. Rev. (2001)
- Salmonella pathogenicity island 2 mediates protection of intracellular Salmonella from reactive nitrogen intermediates. Chakravortty, D., Hansen-Wester, I., Hensel, M. J. Exp. Med. (2002)
- Hypoxia-reoxygenation triggers coronary vasospasm in isolated bovine coronary arteries via tyrosine nitration of prostacyclin synthase. Zou, M.H., Bachschmid, M. J. Exp. Med. (1999)
- The physiology and pathophysiology of nitric oxide in the brain. Guix, F.X., Uribesalgo, I., Coma, M., Muñoz, F.J. Prog. Neurobiol. (2005)
- Increased peroxynitrite activity in AIDS dementia complex: implications for the neuropathogenesis of HIV-1 infection. Boven, L.A., Gomes, L., Hery, C., Gray, F., Verhoef, J., Portegies, P., Tardieu, M., Nottet, H.S. J. Immunol. (1999)
- Inactivation of NADP+-dependent isocitrate dehydrogenase by peroxynitrite. Implications for cytotoxicity and alcohol-induced liver injury. Lee, J.H., Yang, E.S., Park, J.W. J. Biol. Chem. (2003)
- Excitotoxic brain damage involves early peroxynitrite formation in a model of Huntington's disease in rats: protective role of iron porphyrinate 5,10,15,20-tetrakis (4-sulfonatophenyl)porphyrinate iron (III). Pérez-De La Cruz, V., González-Cortés, C., Galván-Arzate, S., Medina-Campos, O.N., Pérez-Severiano, F., Ali, S.F., Pedraza-Chaverrí, J., Santamaría, A. Neuroscience (2005)
- Elevated nitric oxide/peroxynitrite mechanism for the common etiology of multiple chemical sensitivity, chronic fatigue syndrome, and posttraumatic stress disorder. Pall, M.L., Satterlee, J.D. Ann. N. Y. Acad. Sci. (2001)
- Ischemic cell death in brain neurons. Lipton, P. Physiol. Rev. (1999)
- S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide. Adachi, T., Weisbrod, R.M., Pimentel, D.R., Ying, J., Sharov, V.S., Schöneich, C., Cohen, R.A. Nat. Med. (2004)
- ALS, SOD and peroxynitrite. Beckman, J.S., Carson, M., Smith, C.D., Koppenol, W.H. Nature (1993)
- Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. I. Effects on microbial killing by activated peritoneal macrophages in vitro. Vazquez-Torres, A., Jones-Carson, J., Mastroeni, P., Ischiropoulos, H., Fang, F.C. J. Exp. Med. (2000)
- Nitric oxide mediates murine cytomegalovirus-associated pneumonitis in lungs that are free of the virus. Tanaka, K., Nakazawa, H., Okada, K., Umezawa, K., Fukuyama, N., Koga, Y. J. Clin. Invest. (1997)
- Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite. Szabó, C., Cuzzocrea, S., Zingarelli, B., O'Connor, M., Salzman, A.L. J. Clin. Invest. (1997)
- Nitric oxide: a mediator in rat tubular hypoxia/reoxygenation injury. Yu, L., Gengaro, P.E., Niederberger, M., Burke, T.J., Schrier, R.W. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates. St John, G., Brot, N., Ruan, J., Erdjument-Bromage, H., Tempst, P., Weissbach, H., Nathan, C. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Superoxide dismutase and the death of motoneurons in ALS. Beckman, J.S., Estévez, A.G., Crow, J.P., Barbeito, L. Trends Neurosci. (2001)
- Nitric oxide production and perivascular nitration in brain after carbon monoxide poisoning in the rat. Ischiropoulos, H., Beers, M.F., Ohnishi, S.T., Fisher, D., Garner, S.E., Thom, S.R. J. Clin. Invest. (1996)
- Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death. Mungrue, I.N., Gros, R., You, X., Pirani, A., Azad, A., Csont, T., Schulz, R., Butany, J., Stewart, D.J., Husain, M. J. Clin. Invest. (2002)
- Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects against ischemia-reperfusion injury in rats. Lefer, D.J., Scalia, R., Campbell, B., Nossuli, T., Hayward, R., Salamon, M., Grayson, J., Lefer, A.M. J. Clin. Invest. (1997)
- Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion. Szabó, C., Dawson, V.L. Trends Pharmacol. Sci. (1998)
- A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice. Grohmann, U., Fallarino, F., Bianchi, R., Orabona, C., Vacca, C., Fioretti, M.C., Puccetti, P. J. Exp. Med. (2003)
- Degradation of biomaterials by phagocyte-derived oxidants. Sutherland, K., Mahoney, J.R., Coury, A.J., Eaton, J.W. J. Clin. Invest. (1993)
- Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability. Rajagopalan, S., Meng, X.P., Ramasamy, S., Harrison, D.G., Galis, Z.S. J. Clin. Invest. (1996)
- CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice. Fallarino, F., Bianchi, R., Orabona, C., Vacca, C., Belladonna, M.L., Fioretti, M.C., Serreze, D.V., Grohmann, U., Puccetti, P. J. Exp. Med. (2004)
- Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors. Scott, G.S., Spitsin, S.V., Kean, R.B., Mikheeva, T., Koprowski, H., Hooper, D.C. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Uric acid protects against secondary damage after spinal cord injury. Scott, G.S., Cuzzocrea, S., Genovese, T., Koprowski, H., Hooper, D.C. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis and multiple sclerosis. Hooper, D.C., Spitsin, S., Kean, R.B., Champion, J.M., Dickson, G.M., Chaudhry, I., Koprowski, H. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice. Muscoli, C., Cuzzocrea, S., Ndengele, M.M., Mollace, V., Porreca, F., Fabrizi, F., Esposito, E., Masini, E., Matuschak, G.M., Salvemini, D. J. Clin. Invest. (2007)
- Prevention of peroxynitrite-induced apoptosis of motor neurons and PC12 cells by tyrosine-containing peptides. Ye, Y., Quijano, C., Robinson, K.M., Ricart, K.C., Strayer, A.L., Sahawneh, M.A., Shacka, J.J., Kirk, M., Barnes, S., Accavitti-Loper, M.A., Radi, R., Beckman, J.S., Estévez, A.G. J. Biol. Chem. (2007)
- Inhibition of complex III promotes loss of Ca2+ dependence for mitochondrial superoxide formation and permeability transition evoked by peroxynitrite. Guidarelli, A., Cerioni, L., Cantoni, O. J. Cell. Sci. (2007)
- Mechanism of nitrite formation by nitrate photolysis in aqueous solutions: the role of peroxynitrite, nitrogen dioxide, and hydroxyl radical. Goldstein, S., Rabani, J. J. Am. Chem. Soc. (2007)
- Peroxynitrite: a strategic linchpin of opioid analgesic tolerance. Salvemini, D., Neumann, W.L. Trends Pharmacol. Sci. (2009)
- Inducible nitric oxide synthase is required in alcohol-induced liver injury: studies with knockout mice. McKim, S.E., Gäbele, E., Isayama, F., Lambert, J.C., Tucker, L.M., Wheeler, M.D., Connor, H.D., Mason, R.P., Doll, M.A., Hein, D.W., Arteel, G.E. Gastroenterology (2003)
- Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. Keller, J.N., Kindy, M.S., Holtsberg, F.W., St Clair, D.K., Yen, H.C., Germeyer, A., Steiner, S.M., Bruce-Keller, A.J., Hutchins, J.B., Mattson, M.P. J. Neurosci. (1998)
- Caspase-2 mediates neuronal cell death induced by beta-amyloid. Troy, C.M., Rabacchi, S.A., Friedman, W.J., Frappier, T.F., Brown, K., Shelanski, M.L. J. Neurosci. (2000)
- Peroxynitrite induces integrin-dependent adhesion of human neutrophils to endothelial cells via activation of the Raf-1/MEK/Erk pathway. Zouki, C., Zhang, S.L., Chan, J.S., Filep, J.G. FASEB J. (2001)
- iNOS-derived NO and nox2-derived superoxide confer tolerance to excitotoxic brain injury through peroxynitrite. Kawano, T., Kunz, A., Abe, T., Girouard, H., Anrather, J., Zhou, P., Iadecola, C. J. Cereb. Blood Flow Metab. (2007)
- Nitrosative stress and pharmacological modulation of heart failure. Pacher, P., Schulz, R., Liaudet, L., Szabó, C. Trends Pharmacol. Sci. (2005)
- Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase. Liaudet, L., Soriano, F.G., Szabó, E., Virág, L., Mabley, J.G., Salzman, A.L., Szabo, C. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts. MacMillan-Crow, L.A., Crow, J.P., Kerby, J.D., Beckman, J.S., Thompson, J.A. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Peroxynitrite, the breakdown product of nitric oxide, is beneficial in blood cardioplegia but injurious in crystalloid cardioplegia. Ronson, R.S., Thourani, V.H., Ma, X.L., Katzmark, S.L., Han, D., Zhao, Z.Q., Nakamura, M., Guyton, R.A., Vinten-Johansen, J. Circulation (1999)