Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

thiamine 2-[3-[(4-amino-2-methyl- pyrimidin-5...

Synonyms: Aneurine, Begiolan, Betabion, Bevitine, Eskaphen, ...

Day, E. et al., Tunc-Ozdemir, M. et al., Gibson, G.E. et al., Ahn, I.P. et al., Vogl, C. et al., et al.

Il-Pyung Ahn, Soonok Kim, John P. Blass, Seok-Cheol Suh, Yong-Hwan Lee, Gary E. Gibson,

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Psychiatry related information on Aneurin

SEARCH STRATEGY: Trials were identified from the latest updated search of the Specialized Register of the Cochrane Dementia and Cognitive Improvement Group on 3 February 2003 using the terms "(thiamin* or aneurin*) and (Korsakoff* or Wernicke* or alcohol*) [1].

High impact information on Aneurin

Reactions of metals with vitamins. I. Crystal and molecular structure of thiaminium tetrachlorocadmate monohydrate [2].
Aneurin Bevan on the NHS [3].

Associations of Aneurin with other chemical compounds

Adding thiamine or more absorbable forms of thiamine to tested treatments for the abnormality in glucose metabolism in AD may increase their efficacy [4].
Because thiamin could protect the salicylic acid induction-deficient1 mutant against oxidative stress, thiamin-induced oxidative protection is likely independent of salicylic acid signaling or accumulation [5].

Gene context of Aneurin

Our results indicated that priming is an important cellular mechanism in SAR by thiamine and requires hydrogen peroxide and intact NPR1 [6].
Upon addition of thiamine, the thi9(+) mRNA becomes undetectable within minutes, whereas the Thi9 protein appears to be stable [7].

References

Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse. Day, E., Bentham, P., Callaghan, R., Kuruvilla, T., George, S. Cochrane database of systematic reviews (Online) (2004) [Pubmed]
Reactions of metals with vitamins. I. Crystal and molecular structure of thiaminium tetrachlorocadmate monohydrate. Richardson, M.F., Franklin, K., Thompson, D.M. J. Am. Chem. Soc. (1975) [Pubmed]
Aneurin Bevan on the NHS. Maxwell, R. BMJ (1992) [Pubmed]
Thiamine-dependent processes and treatment strategies in neurodegeneration. Gibson, G.E., Blass, J.P. Antioxid. Redox Signal. (2007) [Pubmed]
Thiamin confers enhanced tolerance to oxidative stress in Arabidopsis. Tunc-Ozdemir, M., Miller, G., Song, L., Kim, J., Sodek, A., Koussevitzky, S., Misra, A.N., Mittler, R., Shintani, D. Plant Physiol. (2009) [Pubmed]
Vitamin B1-induced priming is dependent on hydrogen peroxide and the NPR1 gene in Arabidopsis. Ahn, I.P., Kim, S., Lee, Y.H., Suh, S.C. Plant Physiol. (2007) [Pubmed]
Characterization of Thi9, a novel thiamine (Vitamin B1) transporter from Schizosaccharomyces pombe. Vogl, C., Klein, C.M., Batke, A.F., Schweingruber, M.E., Stolz, J. J. Biol. Chem. (2008) [Pubmed]

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