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Chemical Compound Review

AG-G-10149     hydroxymethylimino-methyl- oxido-azanium

Synonyms: AC1L1XLP, CTK5A9432, 590-96-5, hydroxymethylimino-methyl-oxidoazanium, Methanol,1-(2-methyl-2-oxidodiazenyl)-
 
 
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Disease relevance of METHYLAZOXYMETHANOL

 

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Chemical compound and disease context of METHYLAZOXYMETHANOL

 

Biological context of METHYLAZOXYMETHANOL

 

Anatomical context of METHYLAZOXYMETHANOL

 

Associations of METHYLAZOXYMETHANOL with other chemical compounds

 

Gene context of METHYLAZOXYMETHANOL

 

Analytical, diagnostic and therapeutic context of METHYLAZOXYMETHANOL

References

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  2. Exocrine pancreatic neoplasms induced by methylazoxymethanol acetate in the guppy Poecilia reticulata. Fournie, J.W., Hawkins, W.E., Overstreet, R.M., Walker, W.W. J. Natl. Cancer Inst. (1987) [Pubmed]
  3. Induction of hepatic tumors in a teleost (Oryzias latipes) after treatment with methylazoxymethanol acetate: brief communication. Aoki, K., Matsudaira, H. J. Natl. Cancer Inst. (1977) [Pubmed]
  4. Leiomyomas and leiomyosarcomas of the kidney in 4-day-old BUF rats given methylazoxymethanol acetate intraperitoneally. Reuber, M.D. J. Natl. Cancer Inst. (1976) [Pubmed]
  5. Drug-induced hypergastrinemia: absence of trophic effects on colonic carcinoma in rats. Pinson, D.M., Havu, N., Sztern, M.I., Mattsson, H., Looney, G.A., Kimler, B.F., Hurwitz, A. Gastroenterology (1995) [Pubmed]
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  11. Acute effects of dietary cholic acid and methylazoxymethanol acetate on colon epithelial cell proliferation; metabolism of bile salts and neutral sterols in conventional and germfree SD rats. Weidema, W.F., Deschner, E.E., Cohen, B.I., DeCosse, J.J. J. Natl. Cancer Inst. (1985) [Pubmed]
  12. Induction of colon tumors in 1,2-dimethylhydrazine-resistant Lobund Wistar rats by methylazoxymethanol acetate. Pollard, M., Zedeck, M.S. J. Natl. Cancer Inst. (1978) [Pubmed]
  13. Effect of high-fat diet on colon carcinogenesis in F344 rats treated with 1,2-dimethylhydrazine, methylazoxymethanol acetate, or methylnitrosourea. Reddy, B.S., Watanabe, K., Weisburger, J.H. Cancer Res. (1977) [Pubmed]
  14. Mutagenicity of the naturally occurring carcinogen cycasin and synthetic methylazoxymethanol conjugates in Salmonella typhimurium. Matsushima, T., Matsumoto, H., Shirai, A., Sawamura, M., Sugimura, T. Cancer Res. (1979) [Pubmed]
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  17. Fetal methylazoxymethanol acetate-induced lesions cause reductions in dopamine receptor-mediated catalepsy and stereotypy. Sanberg, P.R., Pevsner, J., Autuono, P.G., Coyle, J.T. Neuropharmacology (1985) [Pubmed]
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  21. Methylazoxymethanol acetate-induced apoptosis in the external granule cell layer of the developing cerebellum of the rat is associated with strong c-Jun expression and formation of high molecular weight c-Jun complexes. Ferrer, I., Pozas, E., Marti, M., Blanco, R., Planas, A.M. J. Neuropathol. Exp. Neurol. (1997) [Pubmed]
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  23. Megalocytosis and other abnormalities expressed during proliferation in regenerating liver of rats treated with methylazoxymethanol acetate prior to partial hepatectomy. Zedeck, M.S., Sternberg, S.S. Cancer Res. (1975) [Pubmed]
  24. Fatty acid-stimulated oxidation of methylazoxymethanol by rat colonic mucosa. Craven, P.A., Neidig, M., DeRubertis, F.R. Cancer Res. (1985) [Pubmed]
  25. Inhibition of methylazoxymethanol-induced intestinal tumors in the rat by pyrazole with paradoxical effects on skin and kidney. Notman, J., Tan, Q.H., Zedeck, M.S. Cancer Res. (1982) [Pubmed]
  26. Differences in the acute response of the various segments ofrat intestine to treatment with the intestinal carcinogen, methylazoxymethanol acetate. Zedeck, M.S., Grab, D.J., Sternberg, S.S. Cancer Res. (1977) [Pubmed]
  27. GABAA receptors reorganize when layer 4 in ferret somatosensory cortex is disrupted by methylazoxymethanol (MAM). Jablonska, B., Smith, A.L., Palmer, S.L., Noctor, S.C., Juliano, S.L. Cereb. Cortex (2004) [Pubmed]
  28. Properties and malignant transformation of established rat liver parenchymal cells in culture. Borenfreund, E., Higgins, P.J., Steinglass, M., Bendich, A. J. Natl. Cancer Inst. (1975) [Pubmed]
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  30. Expression of actin and desmin in experimentally induced hepatic lesions and neoplasms from medaka (Oryzias latipes). Bunton, T.E. Carcinogenesis (1995) [Pubmed]
  31. Inhibitory effect of magnesium hydroxide on methylazoxymethanol acetate-induced large bowel carcinogenesis in male F344 rats. Tanaka, T., Shinoda, T., Yoshimi, N., Niwa, K., Iwata, H., Mori, H. Carcinogenesis (1989) [Pubmed]
  32. No involvement of APC gene mutations in ulcerative colitis-associated rat colon carcinogenesis induced by 1-hydroxyanthraquinone and methylazoxymethanol acetate. Suzui, M., Ushijima, T., Yoshimi, N., Nakagama, H., Hara, A., Sugimura, T., Nagao, M., Mori, H. Mol. Carcinog. (1997) [Pubmed]
  33. Bcl-2 and Bax expression following methylazoxymethanol acetate-induced apoptosis in the external granule cell layer of the developing rat cerebellum. López, E., Pozas, E., Rivera, R., Ferrer, I. Brain Res. Dev. Brain Res. (1999) [Pubmed]
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  35. Non-alcohol dehydrogenase-mediated metabolism of methylazoxymethanol in the deer mouse, Peromyscus maniculatus. Fiala, E.S., Caswell, N., Sohn, O.S., Felder, M.R., McCoy, G.D., Weisburger, J.H. Cancer Res. (1984) [Pubmed]
  36. Effect of colostomy on intestinal carcinogenesis by methylazoxymethanol acetate in rats. Matsubara, N., Mori, H., Hirono, I. J. Natl. Cancer Inst. (1978) [Pubmed]
  37. Increased secretion of the amino-terminal fragment of amyloid precursor protein in brains of rats with a constitutive up-regulation of protein kinase C. Caputi, A., Barindelli, S., Pastorino, L., Cimino, M., Buxbaum, J.D., Cattabeni, F., Di Luca, M. J. Neurochem. (1997) [Pubmed]
  38. Alteration of mouse cerebellar circuits following methylazoxymethanol treatment during development: immunohistochemistry of GABAergic elements and electron microscopic study. de Barry, J., Gombos, G., Klupp, T., Hamori, J. J. Comp. Neurol. (1987) [Pubmed]
 
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