Chemical Compound Review:
NE-100 N,N-diethyl-2-(4-methoxy-3- phenethyloxy...
Synonyms:
SureCN2729151, AC1L3OPK, CID119381, DCL000893, NE 100, ...
This record was replaced with 119382.
- NE-100, a novel sigma receptor ligand: effect on phencyclidine-induced behaviors in rats, dogs and monkeys. Okuyama, S., Imagawa, Y., Sakagawa, T., Nakazato, A., Yamaguchi, K., Katoh, M., Yamada, S., Araki, H., Otomo, S. Life Sci. (1994)
- NE-100, a novel sigma receptor ligand: in vivo tests. Okuyama, S., Imagawa, Y., Ogawa, S., Araki, H., Ajima, A., Tanaka, M., Muramatsu, M., Nakazato, A., Yamaguchi, K., Yoshida, M. Life Sci. (1993)
- Behavioral evidence for modulation by sigma ligands of (+)MK-801-induced hyperlocomotion in monoamine-depleted mice. Okuyama, S., Imagawa, Y., Tomisawa, K. Neuropharmacology (1996)
- Metabotropic neurosteroid/sigma-receptor involved in stimulation of nociceptor endings of mice. Ueda, H., Inoue, M., Yoshida, A., Mizuno, K., Yamamoto, H., Maruo, J., Matsuno, K., Mita, S. J. Pharmacol. Exp. Ther. (2001)
- Involvement of dopamine, N-methyl-D-aspartate and sigma receptor mechanisms in methamphetamine-induced anticipatory activity rhythm in rats. Shibata, S., Ono, M., Fukuhara, N., Watanabe, S. J. Pharmacol. Exp. Ther. (1995)
- Differences in cytochrome P450 forms involved in the metabolism of N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100), a novel sigma ligand, in human liver and intestine. Yamamoto, T., Hagima, N., Nakamura, M., Kohno, Y., Nagata, K., Yamazoe, Y. Drug Metab. Dispos. (2003)
- NE-100, a novel potent sigma ligand, preferentially binds to sigma 1 binding sites in guinea pig brain. Chaki, S., Tanaka, M., Muramatsu, M., Otomo, S. Eur. J. Pharmacol. (1994)
- Characteristics of binding of [3H]NE-100, a novel sigma-receptor ligand, to guinea-pig brain membranes. Tanaka, M., Shirasaki, T., Kaku, S., Muramatsu, M., Otomo, S. Naunyn Schmiedebergs Arch. Pharmacol. (1995)
- Prediction of differences in in vivo oral clearance of N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl] ethylamine monohydrochloride (NE-100) between extensive and poor metabolizers from in vitro metabolic data in human liver microsomes lacking CYP2D6 activity and recombinant CYPs. Yamamoto, T., Hagima, N., Nakamura, M., Kohno, Y., Nagata, K., Yamazoe, Y. Xenobiotica (2004)
- In vivo regulation of serotonin 5-HT2A receptors in rat brain by subchronic administration of sigma receptor ligand NE-100. Hashimoto, K., Narita, N., Tomitaka, S., Iyo, M., Minabe, Y. Life Sci. (1997)
- Prediction of oral clearance from in vitro metabolic data using recombinant CYPs: comparison among well-stirred, parallel-tube, distributed and dispersion models. Yamamoto, T., Itoga, H., Kohno, Y., Nagata, K., Yamazoe, Y. Xenobiotica (2005)
- NE-100, a novel sigma ligand: effects on [3H]TCP binding to intact primary cultured neuronal cells. Yamamoto, H., Yamamoto, T., Sagi, N., Okuyama, S., Kawai, N., Baba, A., Moroji, T. Life Sci. (1995)
- Synthesis and preliminary evaluation of [11C]NE-100 labeled in two different positions as a PET sigma receptor ligand. Ishiwata, K., Noguchi, J., Ishii, S., Hatano, K., Ito, K., Nabeshima, T., Senda, M. Nucl. Med. Biol. (1998)
- Dehydroepiandrosterone alleviates copulatory disorder induced by social stress in male rats. Mizuno, T., Yotsuyanagi, S., Nagasaka, Y., Namiki, M. The journal of sexual medicine. (2006)
- Effect of NE-100, a novel sigma receptor ligand, on phencyclidine- induced delayed cognitive dysfunction in rats. Okuyama, S., Ogawa, S., Nakazato, A., Tomizawa, K. Neurosci. Lett. (1995)
- Sigma ligands stimulate GTPase activity in mouse prefrontal membranes: evidence for the existence of metabotropic sigma receptor. Tokuyama, S., Hirata, K., Ide, A., Ueda, H. Neurosci. Lett. (1997)
- Effects of a novel, selective, sigma1-ligand, MS-377, on phencyclidine-induced behaviour. Takahashi, S., Takagi, K., Horikomi, K. Naunyn Schmiedebergs Arch. Pharmacol. (2001)
- Ultrasensitive determination of NE-100, a novel sigma ligand, in human plasma by liquid chromatography and electrospray ionization tandem mass spectrometry combined with a column-switching technique. Yamaguchi, J., Watanabe, Y., Ohmichi, M., Jingu, S., Ogawa, N., Kokatsu, J., Fukushima, K., Goto, J. J. Chromatogr. B Biomed. Sci. Appl. (1999)