Chemical Compound Review:
Favistan 1-methyl-3H-imidazole-2-thione
Synonyms:
Mercazol, Methizol, Tapazole, Thimazol, Thyrozol, ...
- Induction of circulating activated suppressor-like T cells by methimazole therapy for Graves' disease. Tötterman, T.H., Karlsson, F.A., Bengtsson, M., Mendel-Hartvig, I. N. Engl. J. Med. (1987)
- Relation between therapy for hyperthyroidism and the course of Graves' ophthalmopathy. Bartalena, L., Marcocci, C., Bogazzi, F., Manetti, L., Tanda, M.L., Dell'Unto, E., Bruno-Bossio, G., Nardi, M., Bartolomei, M.P., Lepri, A., Rossi, G., Martino, E., Pinchera, A. N. Engl. J. Med. (1998)
- Production rates and turnover of triiodothyronine in rat-developing cerebral cortex and cerebellum. Responses to hypothyroidism. Silva, J.E., Matthews, P.S. J. Clin. Invest. (1984)
- Role of granulocyte oxygen products in damage of Schistosoma mansoni eggs in vitro. Kazura, J.W., de Brito, P., Rabbege, J., Aikawa, M. J. Clin. Invest. (1985)
- Influence of methimazole on murine thyroiditis. Evidence for immunosuppression in vivo. Davies, T.F., Weiss, I., Gerber, M.A. J. Clin. Invest. (1984)
- Olfaction and peripheral olfactory connections in methimazole-treated rats. Xu, W., Slotnick, B. Behav. Brain Res. (1999)
- Perinatal hypothyroidism effects on neuromotor competence, novelty-directed exploratory and anxiety-related behaviour and learning in rats. Darbra, S., Garau, A., Balada, F., Sala, J., Martí-Carbonell, M.A. Behav. Brain Res. (2003)
- Gender-specific changes in thyroid hormone-glucuronidating enzymes in rat liver during short-term fasting and long-term food restriction. Visser, T.J., van Haasteren, G.A., Linkels, E., Kaptein, E., van Toor, H., de Greef, W.J. Eur. J. Endocrinol. (1996)
- Reversible cerebral hypoperfusion observed with Tc-99m HMPAO SPECT in reversible dementia caused by hypothyroidism. Kinuya, S., Michigishi, T., Tonami, N., Aburano, T., Tsuji, S., Hashimoto, T. Clinical nuclear medicine. (1999)
- Occurrence of ophthalmopathy after treatment for Graves' hyperthyroidism. The Thyroid Study Group. Tallstedt, L., Lundell, G., Tørring, O., Wallin, G., Ljunggren, J.G., Blomgren, H., Taube, A. N. Engl. J. Med. (1992)
- Carbimazole and the autoimmune response in Graves' disease. McGregor, A.M., Petersen, M.M., McLachlan, S.M., Rooke, P., Smith, B.R., Hall, R. N. Engl. J. Med. (1980)
- Agranulocytosis associated with antithyroid drugs. Effects of patient age and drug dose. Cooper, D.S., Goldminz, D., Levin, A.A., Ladenson, P.W., Daniels, G.H., Molitch, M.E., Ridgway, E.C. Ann. Intern. Med. (1983)
- Multiple changes in thyroid function in patients with chronic active HCV hepatitis treated with recombinant interferon-alpha. Roti, E., Minelli, R., Giuberti, T., Marchelli, S., Schianchi, C., Gardini, E., Salvi, M., Fiaccadori, F., Ugolotti, G., Neri, T.M., Braverman, L.E. Am. J. Med. (1996)
- Insulin autoimmunity as a cause of hypoglycemia. Benson, E.A., Ho, P., Wang, C., Wu, P.C., Fredlund, P.N., Yueng, R.T. Arch. Intern. Med. (1984)
- Effect of methimazole, with or without L-thyroxine, on remission rates in Graves' disease. Rittmaster, R.S., Abbott, E.C., Douglas, R., Givner, M.L., Lehmann, L., Reddy, S., Salisbury, S.R., Shlossberg, A.H., Tan, M.H., York, S.E. J. Clin. Endocrinol. Metab. (1998)
- Intrathyroidal concentrations of methimazole in patients with Graves' disease. Jansson, R., Dahlberg, P.A., Johansson, H., Lindström, B. J. Clin. Endocrinol. Metab. (1983)
- Oxidative decarboxylation of free and peptide-linked amino acids in phagocytizing guinea pig granulocytes. Adeniyi-Jones, S.K., Karnovsky, M.L. J. Clin. Invest. (1981)
- Association between the DRB1*08032 histocompatibility antigen and methimazole-induced agranulocytosis in Japanese patients with Graves disease. Tamai, H., Sudo, T., Kimura, A., Mukuta, T., Matsubayashi, S., Kuma, K., Nagataki, S., Sasazuki, T. Ann. Intern. Med. (1996)
- Modulation by the thyroid state of intracellular calcium and contractility in ferret ventricular muscle. MacKinnon, R., Gwathmey, J.K., Allen, P.D., Briggs, G.M., Morgan, J.P. Circ. Res. (1988)
- Postnatal mitochondrial differentiation in rat liver. Regulation by thyroid hormones of the beta-subunit of the mitochondrial F1-ATPase complex. Izquierdo, J.M., Luis, A.M., Cuezva, J.M. J. Biol. Chem. (1990)
- Methimazole prevents induction of experimental systemic lupus erythematosus in mice. Singer, D.S., Kohn, L.D., Zinger, H., Mozes, E. J. Immunol. (1994)
- Phenyl methimazole inhibits TNF-alpha-induced VCAM-1 expression in an IFN regulatory factor-1-dependent manner and reduces monocytic cell adhesion to endothelial cells. Dagia, N.M., Harii, N., Meli, A.E., Sun, X., Lewis, C.J., Kohn, L.D., Goetz, D.J. J. Immunol. (2004)
- Properties of expressed and native flavin-containing monooxygenases: evidence of multiple forms in rabbit liver and lung. Lawton, M.P., Kronbach, T., Johnson, E.F., Philpot, R.M. Mol. Pharmacol. (1991)
- Treatment of methimazole-induced agranulocytosis using recombinant human granulocyte colony-stimulating factor (rhG-CSF). Tamai, H., Mukuta, T., Matsubayashi, S., Fukata, S., Komaki, G., Kuma, K., Kumagai, L.F., Nagataki, S. J. Clin. Endocrinol. Metab. (1993)
- Identification and characterization of novel genes modulated in the thyroid of dogs treated with methimazole and propylthiouracil. Wilkin, F., Savonet, V., Radulescu, A., Petermans, J., Dumont, J.E., Maenhaut, C. J. Biol. Chem. (1996)
- Thyroid hormone stimulation of NADPH P450 reductase expression in liver and extrahepatic tissues. Regulation by multiple mechanisms. Ram, P.A., Waxman, D.J. J. Biol. Chem. (1992)
- Mechanism of iodide-dependent catalatic activity of thyroid peroxidase and lactoperoxidase. Magnusson, R.P., Taurog, A., Dorris, M.L. J. Biol. Chem. (1984)
- Reactions of purified hog thyroid peroxidase with H2O2, tyrosine, and methylmercaptoimidazole (goitrogen) in comparison with bovine lactoperoxidase. Ohtaki, S., Nakagawa, H., Nakamura, M., Yamazaki, I. J. Biol. Chem. (1982)
- Iodide binding and regulation of lactoperoxidase activity toward thyroid goitrogens. Michot, J.L., Nunez, J., Johnson, M.L., Irace, G., Edelhoch, H. J. Biol. Chem. (1979)
- Alternative processing events in human FMO genes. Lattard, V., Zhang, J., Cashman, J.R. Mol. Pharmacol. (2004)
- Coupling of iodotyrosine catalyzed by human thyroid peroxidase in vitro. Sugawara, M. J. Clin. Endocrinol. Metab. (1985)
- Analysis of IL-2 and IL-6 binding to peripheral blood lymphocytes in Graves disease: relationship with disease activity. Corrales, J.J., Orfao, A., López, A., Mories, M.T., Miralles, J.M., Ciudad, J. Cytometry. (1997)
- Influence of hyperthyroidism on growth hormone secretion. Valcavi, R., Dieguez, C., Zini, M., Muruais, C., Casanueva, F., Portioli, I. Clin. Endocrinol. (Oxf) (1993)
- Methimazole therapy in Graves' disease influences the abnormal expression of CD69 (early activation antigen) on T cells. Corrales, J.J., López, A., Ciudad, J., Mories, M.T., Miralles, J.M., Orfao, A. J. Endocrinol. (1997)
- Frequency of antineutrophil cytoplasmic antibody in Graves' disease patients treated with methimazole. Gumà, M., Salinas, I., Reverter, J.L., Roca, J., Valls-Roc, M., Juan, M., Olivé, A. J. Clin. Endocrinol. Metab. (2003)
- Enhanced activity of the purine nucleotide cycle of the exercising muscle in patients with hyperthyroidism. Fukui, H., Taniguchi , S., Ueta, Y., Yoshida, A., Ohtahara, A., Hisatome, I., Shigemasa, C. J. Clin. Endocrinol. Metab. (2001)
- Arterial embolization: a novel approach to thyroid ablative therapy for Graves' disease. Xiao, H., Zhuang, W., Wang, S., Yu, B., Chen, G., Zhou, M., Wong, N.C. J. Clin. Endocrinol. Metab. (2002)
- Methimazole has no dose-related effect on the intensity of the intrathyroidal autoimmune process in relapsing Graves' disease. Paschke, R., Vogg, M., Kristoferitsch, R., Aktuna, D., Wawschinek, O., Eber, O., Usadel, K.H. J. Clin. Endocrinol. Metab. (1995)
- Methimazole pharmacology in man: studies using a newly developed radioimmunoassay for methimazole. Cooper, D.S., Bode, H.H., Nath, B., Saxe, V., Maloof, F., Ridgway, E.C. J. Clin. Endocrinol. Metab. (1984)