Disease relevance of Potassium titanium oxide

• Inhalation toxicity of potassium octatitanate fibers (TISMO) in rats following 13 weeks of aerosol exposure [1].
• Effects of surface characteristics of potassium titanate whisker samples on acute lung injury induced by a single intratracheal administration in rats [2].

High impact information on Potassium titanium oxide

• Rats, hamsters, and guinea pigs were exposed by inhalation to different concentrations of potassium octatitanate fibers [3].
• A chronic inhalation toxicity/carcinogenicity study of potassium octatitanate fibers (TISMO) was conducted in male Fischer 344 rats [4].
• The pulmonary effects of long-term inhalation of potassium octatitanate whisker (PT1), one of the durable man-made fibers (MMFs), were examined in rats [5].
• On the other hand, the average thickness of visceral pleura was higher in all asbestos and manmade fiber groups than in the control (2.9 microns), for instance, 36.95 microns in potassium titanate fiber group, 15.90 microns crocidolite group, 13.00 microns basic magnesium sulfate fiber group, and 10.45 microns in the rockwool group [6].
• Tumors were observed in hamsters that had received basic magnesium sulfate fiber (9/20), metaphosphate fiber (6/20), calcium sulfate fiber (3/20), and fiberglass (2/20) but not in the control, rock wool, or potassium titanate fiber groups [7].

Gene context of Potassium titanium oxide

• An extensive increase in both the TM activity and TM antigen level was also observed on HUVECs treated with potassium titanate whisker or magnesium sulfate whisker for 48 h and 72 h [8].

Analytical, diagnostic and therapeutic context of Potassium titanium oxide

• For validation we here examined toxicity of fine particles from quartz, hydrotalcite, potassium octatitanate, palladium oxide and carbon black with this bioassay [9].

References