Chemical Compound Review:
Melarsen disodiumN2-(4- dioxidoarsorylphenyl)- 1,3,5...
Synonyms:
AG-F-25228, LS-21701, CTK4H5717, AC1L52RE, 3599-28-8, ...
This record was replaced with 79871.
- The role of Trypanosoma brucei MRPA in melarsoprol susceptibility. Alibu, V.P., Richter, C., Voncken, F., Marti, G., Shahi, S., Renggli, C.K., Seebeck, T., Brun, R., Clayton, C. Mol. Biochem. Parasitol. (2006)
- Relative efficacy of melarsen oxide compared with mel Cy (Cymelarsan) when used in combination with difluoromethylornithine in the treatment of trypanosomiasis of the central nervous system. Jennings, F.W. Trans. R. Soc. Trop. Med. Hyg. (1992)
- Trypanothione is the primary target for arsenical drugs against African trypanosomes. Fairlamb, A.H., Henderson, G.B., Cerami, A. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei. Carter, N.S., Berger, B.J., Fairlamb, A.H. J. Biol. Chem. (1995)
- Investigations of the metabolites of the trypanocidal drug melarsoprol. Keiser, J., Ericsson, O., Burri, C. Clin. Pharmacol. Ther. (2000)
- Differential susceptibility of filarial and human erythrocyte glutathione reductase to inhibition by the trivalent organic arsenical melarsen oxide. Müller, S., Walter, R.D., Fairlamb, A.H. Mol. Biochem. Parasitol. (1995)
- Trypanothione reductase from Leishmania donovani. Purification, characterisation and inhibition by trivalent antimonials. Cunningham, M.L., Fairlamb, A.H. Eur. J. Biochem. (1995)
- Structural characterization of monomeric folding intermediates of recombinant human macrophage-colony stimulating factor beta (rhM-CSFbeta) by chemical trapping, chromatographic separation and mass spectrometric peptide mapping. Peter Happersberger, H., Cowgill, C., Glocker, M.O. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2002)
- The interaction of arsenical drugs with dihydrolipoamide and dihydrolipoamide dehydrogenase from arsenical resistant and sensitive strains of Trypanosoma brucei brucei. Fairlamb, A.H., Smith, K., Hunter, K.J. Mol. Biochem. Parasitol. (1992)
- Biosynthesis and uptake of thiamine (vitamin B1) in bloodstream form Trypanosoma brucei brucei and interference of the vitamin with melarsen oxide activity. Stoffel, S.A., Rodenko, B., Schweingruber, A.M., Mäser, P., de Koning, H.P., Schweingruber, M.E. Int. J. Parasitol. (2006)
- Characterisation of melarsen-resistant Trypanosoma brucei brucei with respect to cross-resistance to other drugs and trypanothione metabolism. Fairlamb, A.H., Carter, N.S., Cunningham, M., Smith, K. Mol. Biochem. Parasitol. (1992)
- Effects of various metabolic conditions and of the trivalent arsenical melarsen oxide on the intracellular levels of fructose 2,6-bisphosphate and of glycolytic intermediates in Trypanosoma brucei. Van Schaftingen, E., Opperdoes, F.R., Hers, H.G. Eur. J. Biochem. (1987)