Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

AC1MHKBX (2R,3R,4R,5R)-2-(2-bromo-5,6- dichloro...

Synonyms: CHEMBL515144, GW275175X, OOAVDXDURLPULP-GWOFURMSSA-N, 068606E674D055E8DEF28EFC50682432

Williams, S.L. et al., Underwood, M.R. et al.

Underwood, Ferris, Selleseth, Davis, Drach, Townsend, Biron, Boyd,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of AIDS-179999

We present an initial description of the activity of GW275175X against HCMV, other herpesviruses, and selected nonherpesviruses [1].
In the present study, we have evaluated the in vitro antiviral activity of BDCRB, an analog, GW275175X (175X), and 1263W94 against the replication of HSV-1, HSV-2, VZV, CMV, EBV, HHV-6, and HHV-8 [2].

References

Mechanism of action of the ribopyranoside benzimidazole GW275175X against human cytomegalovirus. Underwood, M.R., Ferris, R.G., Selleseth, D.W., Davis, M.G., Drach, J.C., Townsend, L.B., Biron, K.K., Boyd, F.L. Antimicrob. Agents Chemother. (2004) [Pubmed]
In vitro activities of benzimidazole D- and L-ribonucleosides against herpesviruses. Williams, S.L., Hartline, C.B., Kushner, N.L., Harden, E.A., Bidanset, D.J., Drach, J.C., Townsend, L.B., Underwood, M.R., Biron, K.K., Kern, E.R. Antimicrob. Agents Chemother. (2003) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use

[search][advanced]