Chemical Compound Review:
AC1MHLFF 1,1-dimethyl-3-[(1-pyridin- 2...
Synonyms:
A-1110U, A1110U, A 1110U, 96860-23-0
- 2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (A1110U), a potent inactivator of ribonucleotide reductases of herpes simplex and varicella-zoster viruses and a potentiator of acyclovir. Spector, T., Harrington, J.A., Morrison, R.W., Lambe, C.U., Nelson, D.J., Averett, D.R., Biron, K., Furman, P.A. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Herpes simplex virus type 1 ribonucleotide reductase: selective and synergistic inactivation by A1110U and its iron complex. Porter, D.J., Harrington, J.A., Spector, T. Biochem. Pharmacol. (1990)
- Synergistic topical therapy by acyclovir and A1110U for herpes simplex virus induced zosteriform rash in mice. Lobe, D.C., Spector, T., Ellis, M.N. Antiviral Res. (1991)