Chemical Compound Review:
AdoMet (2S)-2-amino-4- [[(2R,3S,4R,5R)-5-(6...
Synonyms:
Donamet, Ademetionine, SAMe, SAM-e, Sam-Sulfate, ...
This record was replaced with 34756.
- Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis. Marí, M., Colell, A., Morales, A., Pañeda, C., Varela-Nieto, I., García-Ruiz, C., Fernández-Checa, J.C. J. Clin. Invest. (2004)
- Demyelination and single-carbon transfer pathway metabolites during the treatment of acute lymphoblastic leukemia: CSF studies. Surtees, R., Clelland, J., Hann, I. J. Clin. Oncol. (1998)
- A new medical approach to the treatment of osteoarthritis. Report of an open phase IV study with ademetionine (Gumbaral). Berger, R., Nowak, H. Am. J. Med. (1987)
- Rickettsial metK-encoded methionine adenosyltransferase expression in an Escherichia coli metK deletion strain. Driskell, L.O., Tucker, A.M., Winkler, H.H., Wood, D.O. J. Bacteriol. (2005)
- Transsulfuration in an adult with hepatic methionine adenosyltransferase deficiency. Gahl, W.A., Bernardini, I., Finkelstein, J.D., Tangerman, A., Martin, J.J., Blom, H.J., Mullen, K.D., Mudd, S.H. J. Clin. Invest. (1988)
- Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes. Layer, G., Moser, J., Heinz, D.W., Jahn, D., Schubert, W.D. EMBO J. (2003)
- Differential expression of methionine adenosyltransferase genes influences the rate of growth of human hepatocellular carcinoma cells. Cai, J., Mao, Z., Hwang, J.J., Lu, S.C. Cancer Res. (1998)
- Role of abnormal methionine metabolism in alcoholic liver injury. Lu, S.C., Tsukamoto, H., Mato, J.M. Alcohol (2002)
- Methionine utilization in long-term human lymphoid cell lines. Guarini, L., Sturman, J.A., Gaull, G.E., Beratis, N.G. J. Cell. Physiol. (1981)
- Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis. Sandmark, J., Eliot, A.C., Famm, K., Schneider, G., Kirsch, J.F. Biochemistry (2004)
- Regulation of mammalian liver methionine adenosyltransferase. Corrales, F.J., Pérez-Mato, I., Sánchez Del Pino, M.M., Ruiz, F., Castro, C., García-Trevijano, E.R., Latasa, U., Martínez-Chantar, M.L., Martínez-Cruz, A., Avila, M.A., Mato, J.M. J. Nutr. (2002)
- Methionine inhibits developmental aggregation of Myxococcus xanthus by blocking the biosynthesis of S-adenosyl methionine. Shi, W., Zusman, D.R. J. Bacteriol. (1995)
- The role of c-Myb in the up-regulation of methionine adenosyltransferase 2A expression in activated Jurkat cells. Zeng, Z., Yang, H., Huang, Z.Z., Chen, C., Wang, J., Lu, S.C. Biochem. J. (2001)
- Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice. Sibani, S., Melnyk, S., Pogribny, I.P., Wang, W., Hiou-Tim, F., Deng, L., Trasler, J., James, S.J., Rozen, R. Carcinogenesis (2002)
- Conversion of spironolactone to 7 alpha-thiomethylspironolactone by hepatic and renal microsomes. LaCagnin, L.B., Lutsie, P., Colby, H.D. Biochem. Pharmacol. (1987)
- Methionine transport in Yersinia pestis. Montie, D.B., Montie, T.C. J. Bacteriol. (1975)
- Phosphatidylethanolamine N-methyltransferase activity in isolated rod outer segments from bovine retina. Roque, M.E., Giusto, N.M. Exp. Eye Res. (1995)
- Oxygen-independent coproporphyrinogen-III oxidase HemN from Escherichia coli. Layer, G., Verfürth, K., Mahlitz, E., Jahn, D. J. Biol. Chem. (2002)
- The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders. Bottiglieri, T., Hyland, K., Reynolds, E.H. Drugs (1994)
- Cork taint of wines: role of the filamentous fungi isolated from cork in the formation of 2,4,6-trichloroanisole by o methylation of 2,4,6-trichlorophenol. Alvarez-Rodríguez, M.L., López-Ocaña, L., López-Coronado, J.M., Rodríguez, E., Martínez, M.J., Larriba, G., Coque, J.J. Appl. Environ. Microbiol. (2002)
- A glycine N-methyltransferase knockout mouse model for humans with deficiency of this enzyme. Luka, Z., Capdevila, A., Mato, J.M., Wagner, C. Transgenic Res. (2006)
- Tertiary structure of thiopurine methyltransferase from Pseudomonas syringae, a bacterial orthologue of a polymorphic, drug-metabolizing enzyme. Scheuermann, T.H., Lolis, E., Hodsdon, M.E. J. Mol. Biol. (2003)
- Hepatic one-carbon metabolism in early folate deficiency in rats. Balaghi, M., Horne, D.W., Wagner, C. Biochem. J. (1993)
- Double-blind, placebo-controlled pharmacodynamic studies with a nutraceutical and a pharmaceutical dose of ademetionine (SAMe) in elderly subjects, utilizing EEG mapping and psychometry. Arnold, O., Saletu, B., Anderer, P., Assandri, A., di Padova, C., Corrado, M., Saletu-Zyhlarz, G.M. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. (2005)
- Transcriptional analysis of the cyclopropane fatty acid synthase gene of Lactococcus lactis MG1363 at low pH. Budin-Verneuil, A., Maguin, E., Auffray, Y., Ehrlich, S.D., Pichereau, V. FEMS Microbiol. Lett. (2005)