Chemical Compound Review:
MOLI001810 urea
Synonyms:
MOLI001869, AC1L9PH1
- Familial azotemia. Impaired urea excretion despite normal renal function. Hsu, C.H., Kurtz, T.W., Massari, P.U., Ponze, S.A., Chang, B.S. N. Engl. J. Med. (1978)
- Treatment of episodic hyperammonemia in children with inborn errors of urea synthesis. Brusilow, S.W., Danney, M., Waber, L.J., Batshaw, M., Burton, B., Levitsky, L., Roth, K., McKeethren, C., Ward, J. N. Engl. J. Med. (1984)
- Transiently reduced activity of carbamyl phosphate synthetase and ornithine transcarbamylase in liver of children with Reye's syndrome. Brown, T., Hug, G., Lansky, L., Bove, K., Scheve, A., Ryan, M., Brown, H., Schubert, W.K., Partin, J.C., Lloyd-Still, J. N. Engl. J. Med. (1976)
- Risk factors for cerebral edema in children with diabetic ketoacidosis. The Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. Glaser, N., Barnett, P., McCaslin, I., Nelson, D., Trainor, J., Louie, J., Kaufman, F., Quayle, K., Roback, M., Malley, R., Kuppermann, N. N. Engl. J. Med. (2001)
- Microencapsulated genetically engineered live E. coli DH5 cells administered orally to maintain normal plasma urea level in uremic rats. Prakash, S., Chang, T.M. Nat. Med. (1996)
- Alzheimer's disease: insolubility of partially purified paired helical filaments in sodium dodecyl sulfate and urea. Selkoe, D.J., Ihara, Y., Salazar, F.J. Science (1982)
- Prevention of prednisone-induced negative nitrogen balance. Effect of dietary modification on urea generation rate in patients on hemodialysis receiving high-dose glucocorticoids. Cogan, M.G., Sargent, J.A., Yarbrough, S.G., Vincenti, F., Amend, W.J. Ann. Intern. Med. (1981)
- Dysregulation of C/EBP{alpha} by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease. Chiang, M.C., Chen, H.M., Lee, Y.H., Chang, H.H., Wu, Y.C., Soong, B.W., Chen, C.M., Wu, Y.R., Liu, C.S., Niu, D.M., Wu, J.Y., Chen, Y.T., Chern, Y. Hum. Mol. Genet. (2007)
- Beta-amyloid peptides in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Wiltfang, J., Esselmann, H., Smirnov, A., Bibl, M., Cepek, L., Steinacker, P., Mollenhauer, B., Buerger, K., Hampel, H., Paul, S., Neumann, M., Maler, M., Zerr, I., Kornhuber, J., Kretzschmar, H.A., Poser, S., Otto, M. Ann. Neurol. (2003)
- Minimum urine flow rate during water deprivation: importance of the nonurea versus total osmolality in the inner medulla. Soroka, S.D., Chayaraks, S., Cheema-Dhadli, S., Myers, J.A., Rubin, S., Sonnenberg, H., Halperin, M.L. J. Am. Soc. Nephrol. (1997)
- Renal medullary organic osmolytes. Garcia-Perez, A., Burg, M.B. Physiol. Rev. (1991)
- The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein. Kobayashi, K., Sinasac, D.S., Iijima, M., Boright, A.P., Begum, L., Lee, J.R., Yasuda, T., Ikeda, S., Hirano, R., Terazono, H., Crackower, M.A., Kondo, I., Tsui, L.C., Scherer, S.W., Saheki, T. Nat. Genet. (1999)
- The intensity of hemodialysis and the response to erythropoietin in patients with end-stage renal disease. Ifudu, O., Feldman, J., Friedman, E.A. N. Engl. J. Med. (1996)
- Endoscopic biliary drainage for severe acute cholangitis. Lai, E.C., Mok, F.P., Tan, E.S., Lo, C.M., Fan, S.T., You, K.T., Wong, J. N. Engl. J. Med. (1992)
- Treatment of carbamyl phosphate synthetase deficiency with keto analogues of essential amino acids. Batshaw, M., Brusilow, S., Walser, M. N. Engl. J. Med. (1975)
- The spectrum of septic encephalopathy. Definitions, etiologies, and mortalities. Eidelman, L.A., Putterman, D., Putterman, C., Sprung, C.L. JAMA (1996)
- Changes in the electroencephalogram in acute uremia. Effects of parathyroid hormone and brain electrolytes. Guisado, R., Arieff, A.I., Massry, S.G., Lazarowitz, V., Kerian, A. J. Clin. Invest. (1975)
- Genetic polymorphism in C8 beta-chains. Evidence for two unlinked genetic loci for the eighth component of human complement (C8). Alper, C.A., Marcus, D., Raum, D., Petersen, B.H., Spira, T.J. J. Clin. Invest. (1983)
- Renal ammonia and glutamine metabolism during liver insufficiency-induced hyperammonemia in the rat. Dejong, C.H., Deutz, N.E., Soeters, P.B. J. Clin. Invest. (1993)
- Natural history of symptomatic partial ornithine transcarbamylase deficiency. Rowe, P.C., Newman, S.L., Brusilow, S.W. N. Engl. J. Med. (1986)
- The complete sequence of the mucosal pathogen Ureaplasma urealyticum. Glass, J.I., Lefkowitz, E.J., Glass, J.S., Heiner, C.R., Chen, E.Y., Cassell, G.H. Nature (2000)
- Amino acid acylation: a mechanism of nitrogen excretion in inborn errors of urea synthesis. Brusilow, S., Tinker, J., Batshaw, M.L. Science (1980)
- Effect of captopril on progression to clinical proteinuria in patients with insulin-dependent diabetes mellitus and microalbuminuria. European Microalbuminuria Captopril Study Group. Viberti, G., Mogensen, C.E., Groop, L.C., Pauls, J.F. JAMA (1994)
- Fibronectin alters the phenotypic properties of cultured chick embryo chondroblasts. West, C.M., Lanza, R., Rosenbloom, J., Lowe, M., Holtzer, H., Avdalovic, N. Cell (1979)
- Cloning and characterization of the vasopressin-regulated urea transporter. You, G., Smith, C.P., Kanai, Y., Lee, W.S., Stelzner, M., Hediger, M.A. Nature (1993)
- Antibodies to paired helical filaments in Alzheimer's disease do not recognize normal brain proteins. Ihara, Y., Abraham, C., Selkoe, D.J. Nature (1983)
- Evolution of urea synthesis in vertebrates: the piscine connection. Mommsen, T.P., Walsh, P.J. Science (1989)
- A H+-gated urea channel: the link between Helicobacter pylori urease and gastric colonization. Weeks, D.L., Eskandari, S., Scott, D.R., Sachs, G. Science (2000)
- Hyperglucagonemia and its suppression. Importance in the metabolic control of diabetes. Raskin, P., Unger, R.H. N. Engl. J. Med. (1978)
- Structure of a unique binuclear manganese cluster in arginase. Kanyo, Z.F., Scolnick, L.R., Ash, D.E., Christianson, D.W. Nature (1996)
- An efficient prebiotic synthesis of cytosine and uracil. Robertson, M.P., Miller, S.L. Nature (1995)
- Lack of chemokine receptor CCR1 enhances Th1 responses and glomerular injury during nephrotoxic nephritis. Topham, P.S., Csizmadia, V., Soler, D., Hines, D., Gerard, C.J., Salant, D.J., Hancock, W.W. J. Clin. Invest. (1999)
- Dehydration activates an NF-kappaB-driven, COX2-dependent survival mechanism in renal medullary interstitial cells. Hao, C.M., Yull, F., Blackwell, T., Kömhoff, M., Davis, L.S., Breyer, M.D. J. Clin. Invest. (2000)
- Differential extraction of keratin subunits and filaments from normal human epidermis. Eichner, R., Kahn, M. J. Cell Biol. (1990)
- In vitro binding of the asialoglycoprotein receptor to the beta adaptin of plasma membrane coated vesicles. Beltzer, J.P., Spiess, M. EMBO J. (1991)
- The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. Owen, W.F., Lew, N.L., Liu, Y., Lowrie, E.G., Lazarus, J.M. N. Engl. J. Med. (1993)
- Is blood urea nitrogen as good a guide for hemofiltration as for hemodialysis? De Fremont, J.F., Coevoet, B., Dkhissi, H., Pruna, A., Moriniere, P., Galy, C., Fournier, A. N. Engl. J. Med. (1982)
- Salivary gland hyperglycemic factor: an extrapancreatic source of glucagon-like material. Lawrence, A.M., Tan, S., Hojvat, S., Kirsteins, L. Science (1977)