The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

Dihydronorguaiaretic acid     4-[4-(3,4-dihydroxyphenyl)- 2,3-dimethyl...

Synonyms: NDGA, CHEMBL52, SureCN135976, Bio-0613, CPD-7661, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of Dihydronorguaiaretic acid

 

High impact information on Dihydronorguaiaretic acid

 

Chemical compound and disease context of Dihydronorguaiaretic acid

 

Biological context of Dihydronorguaiaretic acid

 

Anatomical context of Dihydronorguaiaretic acid

 

Associations of Dihydronorguaiaretic acid with other chemical compounds

 

Gene context of Dihydronorguaiaretic acid

 

Analytical, diagnostic and therapeutic context of Dihydronorguaiaretic acid

References

  1. Crm-A, bcl-2 and NDGA inhibit CD95L-induced apoptosis of malignant glioma cells at the level of caspase 8 processing. Wagenknecht, B., Schulz, J.B., Gulbins, E., Weller, M. Cell Death Differ. (1998) [Pubmed]
  2. Mechanisms regulating tumor angiogenesis by 12-lipoxygenase in prostate cancer cells. Nie, D., Krishnamoorthy, S., Jin, R., Tang, K., Chen, Y., Qiao, Y., Zacharek, A., Guo, Y., Milanini, J., Pages, G., Honn, K.V. J. Biol. Chem. (2006) [Pubmed]
  3. Inhibition of bleomycin-induced pulmonary fibrosis by nordihydroguaiaretic acid. The role of alveolar macrophage activation and mediator production. Phan, S.H., Kunkel, S.L. Am. J. Pathol. (1986) [Pubmed]
  4. Involvement of oxidants and oxidant-generating enzyme(s) in tumour-necrosis-factor-alpha-mediated apoptosis: role for lipoxygenase pathway but not mitochondrial respiratory chain. O'Donnell, V.B., Spycher, S., Azzi, A. Biochem. J. (1995) [Pubmed]
  5. Prostaglandin and leukotriene synthesis in mouse ears inflamed by arachidonic acid. Opas, E.E., Bonney, R.J., Humes, J.L. J. Invest. Dermatol. (1985) [Pubmed]
  6. Hydroxyl radical scavengers inhibit human natural killer cell activity. Suthanthiran, M., Solomon, S.D., Williams, P.S., Rubin, A.L., Novogrodsky, A., Stenzel, K.H. Nature (1984) [Pubmed]
  7. Significance of tissue myo-inositol concentrations in metabolic regulation in nerve. Simmons, D.A., Winegrad, A.I., Martin, D.B. Science (1982) [Pubmed]
  8. Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism. Zhou, Y.P., Teng, D., Dralyuk, F., Ostrega, D., Roe, M.W., Philipson, L., Polonsky, K.S. J. Clin. Invest. (1998) [Pubmed]
  9. Tumor necrosis factor-alpha-induced inhibition of phosphatidylcholine synthesis by human type II pneumocytes is partially mediated by prostaglandins. Arias-Díaz, J., Vara, E., García, C., Balibrea, J.L. J. Clin. Invest. (1994) [Pubmed]
  10. Relative contribution of leukotriene B4 to the neutrophil chemotactic activity produced by the resident human alveolar macrophage. Martin, T.R., Raugi, G., Merritt, T.L., Henderson, W.R. J. Clin. Invest. (1987) [Pubmed]
  11. Effect of inhibitors of eicosanoid metabolism on release of [3H]noradrenaline from the human neuroblastoma, SH-SY5Y. Vaughan, P.F., Murphy, M.G., Ball, S.G. J. Neurochem. (1993) [Pubmed]
  12. Masoprocol lowers blood pressure in rats with fructose-induced hypertension. Gowri, M.S., Reaven, G.M., Azhar, S. Am. J. Hypertens. (1999) [Pubmed]
  13. Effect of nordihydroguaiaretic acid on cultured rat and human glioma cell proliferation. Wilson, D.E., DiGianfilippo, A., Ondrey, F.G., Anderson, K.M., Harris, J.E. J. Neurosurg. (1989) [Pubmed]
  14. Treatment of experimental granulomatous uveitis by lipoxygenase and cyclo-oxygenase inhibitors. Rao, N.A., Patchett, R., Fernandez, M.A., Sevanian, A., Kunkel, S.L., Marak, G.E. Arch. Ophthalmol. (1987) [Pubmed]
  15. Effects of lipoxygenase inhibitors in arachidonate-induced sudden death. Roth, D.M., Feduska, R., Lefer, A.M., Smith, J.B. J. Pharm. Pharmacol. (1984) [Pubmed]
  16. Stimulation of tubulin tyrosinolation in rabbit leukocytes evoked by the chemoattractant formyl-methionyl-leucyl-phenylalanine. Nath, J., Flavin, M., Schiffmann, E. J. Cell Biol. (1981) [Pubmed]
  17. Tetra-O-methyl nordihydroguaiaretic acid induces growth arrest and cellular apoptosis by inhibiting Cdc2 and survivin expression. Chang, C.C., Heller, J.D., Kuo, J., Huang, R.C. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  18. Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger. O'Dell, T.J., Hawkins, R.D., Kandel, E.R., Arancio, O. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  19. Tetra-O-methyl nordihydroguaiaretic acid induces G2 arrest in mammalian cells and exhibits tumoricidal activity in vivo. Heller, J.D., Kuo, J., Wu, T.C., Kast, W.M., Huang, R.C. Cancer Res. (2001) [Pubmed]
  20. Corticotropin-releasing factor mRNA in rat thymus and spleen. Aird, F., Clevenger, C.V., Prystowsky, M.B., Redei, E. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  21. Platelet modulation of polymorphonuclear leukocyte shear induced aggregation. Rhee, B.G., Hall, E.R., McIntire, L.V. Blood (1986) [Pubmed]
  22. Nordihydroguaiaretic acid blocks protein transport in the secretory pathway causing redistribution of Golgi proteins into the endoplasmic reticulum. Fujiwara, T., Takami, N., Misumi, Y., Ikehara, Y. J. Biol. Chem. (1998) [Pubmed]
  23. Nature of thrombin-induced sustained increase in cytosolic calcium concentration in cultured endothelial cells. Goligorsky, M.S., Menton, D.N., Laszlo, A., Lum, H. J. Biol. Chem. (1989) [Pubmed]
  24. Various authentic chemoattractants mediating leukocyte adherence inhibition. Thomson, D.M. J. Natl. Cancer Inst. (1984) [Pubmed]
  25. Involvement of 5-lipoxygenase in programmed cell death of cancer cells. Maccarrone, M., Catani, M.V., Agrò, A.F., Melino, G. Cell Death Differ. (1997) [Pubmed]
  26. Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides. Smith, T.J., Stoner, G.D., Yang, C.S. Cancer Res. (1995) [Pubmed]
  27. Endogenous non-cyclooxygenase metabolites of arachidonic acid modulate growth and mRNA levels of immediate-early response genes in rat mesangial cells. Sellmayer, A., Uedelhoven, W.M., Weber, P.C., Bonventre, J.V. J. Biol. Chem. (1991) [Pubmed]
  28. Lipoxygenase activity in rat kidney glomeruli, glomerular epithelial cells, and cortical tubules. Jim, K., Hassid, A., Sun, F., Dunn, M.J. J. Biol. Chem. (1982) [Pubmed]
  29. Inhibition of 5-lipoxygenase blocks IL-1 beta-induced vascular adhesion molecule-1 gene expression in human endothelial cells. Lee, S., Felts, K.A., Parry, G.C., Armacost, L.M., Cobb, R.R. J. Immunol. (1997) [Pubmed]
  30. Mitogenic signaling by epidermal growth factor (EGF), but not platelet-derived growth factor, requires arachidonic acid metabolism in BALB/c 3T3 cells. Modulation of EGF-dependent c-myc expression by prostaglandins. Handler, J.A., Danilowicz, R.M., Eling, T.E. J. Biol. Chem. (1990) [Pubmed]
  31. Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragments. Del Carlo, M., Schwartz, D., Erickson, E.A., Loeser, R.F. Free Radic. Biol. Med. (2007) [Pubmed]
  32. Regulation of the CYP1A1 gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin but not by beta-naphthoflavone or 3-methylcholanthrene is altered in hepatitis C virus replicon-expressing cells. Anderson, G.R., Hasan, A., Yin, H., Qadri, I., Quattrochi, L.C. Mol. Pharmacol. (2006) [Pubmed]
  33. Inhibitory effects of nordihydroguaiaretic acid on ETA-receptor-mediated contractions to endothelin-1 in rat trachea. Henry, P.J. Br. J. Pharmacol. (1994) [Pubmed]
  34. 13-Hydroxyoctadecadienoic acid is the mitogenic signal for linoleic acid-dependent growth in rat hepatoma 7288CTC in vivo. Sauer, L.A., Dauchy, R.T., Blask, D.E., Armstrong, B.J., Scalici, S. Cancer Res. (1999) [Pubmed]
  35. Systemic treatment with tetra-O-methyl nordihydroguaiaretic acid suppresses the growth of human xenograft tumors. Park, R., Chang, C.C., Liang, Y.C., Chung, Y., Henry, R.A., Lin, E., Mold, D.E., Huang, R.C. Clin. Cancer Res. (2005) [Pubmed]
  36. Lipid peroxidation, arachidonic acid and products of the lipoxygenase pathway in ischaemic preconditioning of rat heart. Starkopf, J., Andreasen, T.V., Bugge, E., Ytrehus, K. Cardiovasc. Res. (1998) [Pubmed]
  37. Multiple effects of nordihydroguaiaretic acid on ionic currents in rat isolated type I carotid body cells. Hatton, C.J., Peers, C. Br. J. Pharmacol. (1997) [Pubmed]
  38. An in vivo model for measuring antigen-induced SRS-A-mediated bronchoconstriction and plasma SRS-A levels in the guinea-pig. Anderson, W.H., O'Donnell, M., Simko, B.A., Welton, A.F. Br. J. Pharmacol. (1983) [Pubmed]
 
WikiGenes - Universities