Chemical Compound Review:
Olomucine 2-[[6-(benzylamino)-9-methyl- purin-2...
Synonyms:
olomoucine, UPCMLD-DP136, Lopac-O-0886, Tocris-1284, Kinome_2870, ...
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- The cyclin-dependent kinase (cdk) inhibitors, olomoucine and roscovitine, alter the expression of a molluscan circadian pacemaker. Krucher, N.A., Meijer, L., Roberts, M.H. Cell. Mol. Neurobiol. (1997)
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- Caspase 3-mediated cleavage of p21WAF1/CIP1 associated with the cyclin A-cyclin-dependent kinase 2 complex is a prerequisite for apoptosis in SK-HEP-1 cells. Jin, Y.H., Yoo, K.J., Lee, Y.H., Lee, S.K. J. Biol. Chem. (2000)
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- ERK pathway mediates the activation of Cdk2 in IGF-1-induced proliferation of human osteosarcoma MG-63 cells. Zhang, W., Lee, J.C., Kumar, S., Gowen, M. J. Bone Miner. Res. (1999)
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- Cdk5/p35 and Rho-kinase mediate ephrin-A5-induced signaling in retinal ganglion cells. Cheng, Q., Sasaki, Y., Shoji, M., Sugiyama, Y., Tanaka, H., Nakayama, T., Mizuki, N., Nakamura, F., Takei, K., Goshima, Y. Mol. Cell. Neurosci. (2003)
- Phosphorylation of Sp1 by cyclin-dependent kinase 2 modulates the role of Sp1 in CTP:phosphocholine cytidylyltransferase alpha regulation during the S phase of the cell cycle. Banchio, C., Schang, L.M., Vance, D.E. J. Biol. Chem. (2004)
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- Mitogen-activated protein kinase regulates neurofilament axonal transport. Chan, W.K., Dickerson, A., Ortiz, D., Pimenta, A.F., Moran, C.M., Motil, J., Snyder, S.J., Malik, K., Pant, H.C., Shea, T.B. J. Cell. Sci. (2004)
- The cyclin-dependent kinase inhibitors olomoucine and roscovitine arrest human fibroblasts in G1 phase by specific inhibition of CDK2 kinase activity. Alessi, F., Quarta, S., Savio, M., Riva, F., Rossi, L., Stivala, L.A., Scovassi, A.I., Meijer, L., Prosperi, E. Exp. Cell Res. (1998)
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- Adenovirus-mediated E2F-1 gene transfer induces an apoptotic response in human gastric carcinoma cells that is enhanced by cyclin dependent kinase inhibitors. Atienza, C., Elliott, M.J., Dong, Y.B., Yang, H.L., Stilwell, A., Liu, T.J., McMasters, K.M. Int. J. Mol. Med. (2000)
- Synthetic cyclin dependent kinase inhibitors. New generation of potent anti-cancer drugs. Hajdúch, M., Havlíèek, L., Veselý, J., Novotný, R., Mihál, V., Strnad, M. Adv. Exp. Med. Biol. (1999)
- Identification of plectin as a substrate of p34cdc2 kinase and mapping of a single phosphorylation site. Malecz, N., Foisner, R., Stadler, C., Wiche, G. J. Biol. Chem. (1996)
- Kinase and phosphatase inhibitors cause rapid alterations in microtubule dynamic instability in living cells. Howell, B., Odde, D.J., Cassimeris, L. Cell Motil. Cytoskeleton (1997)
- Hyperphosphorylation at serine 199/202 of tau factor in the gerbil hippocampus after transient forebrain ischemia. Morioka, M., Kawano, T., Yano, S., Kai, Y., Tsuiki, H., Yoshinaga, Y., Matsumoto, J., Maeda, T., Hamada, J., Yamamoto, H., Fukunaga, K., Kuratsu, J. Biochem. Biophys. Res. Commun. (2006)
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