Chemical Compound Review:
saccharin 9,9-dioxo-9$l^{6}-thia-8...
Synonyms:
Kandiset, Madhurin, Sacarina, Sacharin, Sucrette, ...
- Relative risks of saccharin and calorie ingestion. Cohen, B.L. Science (1978)
- Saccharin and other sweeteners: mutagenic properties. Batzinger, R.P., Ou, S.Y., Bueding, E. Science (1977)
- Behaviorally conditioned immunosuppression and murine systemic lupus erythematosus. Ader, R., Cohen, N. Science (1982)
- N-Methyl-N-nitrosourea and saccharin: effects on epithelium of normal human urinary bladder in vitro. El-Gerzawi, S., Heatfield, B.M., Trump, B.F. J. Natl. Cancer Inst. (1982)
- Dose response of saccharin in induction of urinary bladder hyperplasias in Fischer 344 rats pretreated with N-butyl-N-(4-hydroxybutyl)nitrosamine. Nakanishi, K., Hagiwara, A., Shibata, M., Imaida, K., Tatematsu, M., Ito, N. J. Natl. Cancer Inst. (1980)
- Case-control study of decaffeinated coffee consumption and pancreatic cancer. Wynder, E.L., Dieck, G.S., Hall, N.E. Cancer Res. (1986)
- Genetics of behaviour: phenotypic and molecular study of rats derived from high- and low-alcohol consuming lines. Terenina-Rigaldie, E., Moisan, M.P., Colas, A., Beaugé, F., Shah, K.V., Jones, B.C., Mormède, P. Pharmacogenetics (2003)
- Alcohol self-administration in two rat lines selectively bred for extremes in anxiety-related behavior. Henniger, M.S., Spanagel, R., Wigger, A., Landgraf, R., Hölter, S.M. Neuropsychopharmacology (2002)
- Glucose-induced increase in memory performance in patients with schizophrenia. Newcomer, J.W., Craft, S., Fucetola, R., Moldin, S.O., Selke, G., Paras, L., Miller, R. Schizophrenia bulletin. (1999)
- Effects of opiate agonists and antagonists on fluid intake and saccharin choice in the rat. Cooper, S.J. Neuropharmacology (1983)
- Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac. Max, M., Shanker, Y.G., Huang, L., Rong, M., Liu, Z., Campagne, F., Weinstein, H., Damak, S., Margolskee, R.F. Nat. Genet. (2001)
- Saccharin may act as a tumour promoter by inhibiting metabolic cooperation between cells. Trosko, J.E., Dawson, B., Yotti, L.P., Chang, C.C. Nature (1980)
- Cell proliferation in carcinogenesis. Cohen, S.M., Ellwein, L.B. Science (1990)
- Calcitonin: inhibitory effect on eating in rats. Freed, W.J., Perlow, M.J., Wyatt, R.J. Science (1979)
- Genetic effects of impure and pure saccharin in yeast. Moore, C.W., Schmick, A. Science (1979)
- Induction of morphological changes in the urothelium of cultured adult rat bladder by sodium saccharin and sodium cyclamate. Knowles, M.A., Jani, H., Hicks, R.M. Carcinogenesis (1986)
- Effects of sugar on aggressive and inattentive behavior in children with attention deficit disorder with hyperactivity and normal children. Wender, E.H., Solanto, M.V. Pediatrics (1991)
- Bicarbonate-based dental powder, fluoride, and saccharin inhibition of dental caries associated with Streptococcus mutans infection of rats. Tanzer, J.M., Grant, L., McMahon, T. J. Dent. Res. (1988)
- Effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer. Pereira, M.A., Herren, S.L., Britt, A.L. Environ. Health Perspect. (1983)
- Electrical stimulation of the amygdala as a conditioned stimulus in a bait-shyness paradigm. Phillips, A.G., LePiane, F.G. Science (1978)
- Saccharin-induced sister chromatid exchanges in Chinese hamster and human cells. Wolff, S., Rodin, B. Science (1978)
- High frequency oscillations improve nasal mucociliary transport. George, R.J., Moore-Gillon, V., Geddes, D.M. Lancet (1984)
- The importance of synergy between weak carcinogens in the induction of bladder cancer in experimental animals and humans. Hicks, R.M., Chowaniec, J. Cancer Res. (1977)
- Enhancement of oncogenesis in C3H/10T1/2 mouse embryo cell cultures by saccharin. Mondal, S., Brankow, D.W., Heidelberger, C. Science (1978)
- Long-term feeding of sodium saccharin to nonhuman primates: implications for urinary tract cancer. Takayama, S., Sieber, S.M., Adamson, R.H., Thorgeirsson, U.P., Dalgard, D.W., Arnold, L.L., Cano, M., Eklund, S., Cohen, S.M. J. Natl. Cancer Inst. (1998)
- Inhibition of iodinated nerve growth factor binding by the suspected tumor promoters saccharin and cyclamate. Ishii, D.N. J. Natl. Cancer Inst. (1982)
- Suppression of ethanol-reinforced behavior by naltrexone is associated with attenuation of the ethanol-induced increase in dialysate dopamine levels in the nucleus accumbens. Gonzales, R.A., Weiss, F. J. Neurosci. (1998)
- H-ras mutations in rat urinary bladder carcinomas induced by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide and sodium saccharin, sodium ascorbate, or related salts. Masui, T., Mann, A.M., Macatee, T.L., Okamura, T., Garland, E.M., Fujii, H., Pelling, J.C., Cohen, S.M. Cancer Res. (1991)
- Distinction by concanavalin A agglutination between ulceration and repair of rat bladder epithelium induced by freezing or cyclophosphamide and the effect of sodium saccharin. Suzuki, T., Hasegawa, R., Murasaki, G., Cohen, S.M. Cancer Res. (1984)
- Stimulation of DNA synthesis in calcium-deprived T51B liver cells by the tumor promoters phenobarbital, saccharin, and 12-O-tetradecanoylphorbol-13-acetate. Boynton, A.L., Whitfield, J.F. Cancer Res. (1980)
- Inhibition by aspirin of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide initiation and sodium saccharin promotion of urinary bladder carcinogenesis in male F344 rats. Sakata, T., Hasegawa, R., Johansson, S.L., Zenser, T.V., Cohen, S.M. Cancer Res. (1986)
- Design, synthesis, and in vitro inhibitory activity toward human leukocyte elastase, cathepsin G, and proteinase 3 of saccharin-derived sulfones and congeners. Groutas, W.C., Epp, J.B., Venkataraman, R., Kuang, R., Truong, T.M., McClenahan, J.J., Prakash, O. Bioorg. Med. Chem. (1996)
- Polymorphisms in the taste receptor gene (Tas1r3) region are associated with saccharin preference in 30 mouse strains. Reed, D.R., Li, S., Li, X., Huang, L., Tordoff, M.G., Starling-Roney, R., Taniguchi, K., West, D.B., Ohmen, J.D., Beauchamp, G.K., Bachmanov, A.A. J. Neurosci. (2004)
- Saccharin induces morphological changes and enhances prolactin production in GH4C1 cells. Brennessel, B.A., Keyes, K.J. In Vitro Cell. Dev. Biol. (1985)
- Receptor crosstalk: characterization of mice deficient in dopamine D1 and adenosine A2A receptors. Short, J.L., Ledent, C., Drago, J., Lawrence, A.J. Neuropsychopharmacology (2006)
- Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin. Pronin, A.N., Xu, H., Tang, H., Zhang, L., Li, Q., Li, X. Curr. Biol. (2007)
- Morphine tolerance in genetically selected rats induced by chronically elevated saccharin intake. Lieblich, I., Cohen, E., Ganchrow, J.R., Blass, E.M., Bergmann, F. Science (1983)
- Saccharin, cyclamate, and human bladder cancer. No evidence of an association. Kessler, I.I., Clark, J.P. JAMA (1978)
- Behaviorally conditioned suppression of a graft-versus-host response. Bovbjerg, D., Ader, R., Cohen, N. Proc. Natl. Acad. Sci. U.S.A. (1982)