Chemical Compound Review:
Aerodiol (8S,9S,13S,14S,17S)-13- methyl-6,7,8,9,11...
Synonyms:
Estrace, Ovocyclin, Vivelle, estradiol, Oestradiol, ...
Elin Grundberg,
Anna Holmberg,
Osten Ljunggren,
Claes Ohlsson,
Dan Mellström,
Eric Orwoll,
Helena Brändström,
Kristina Akesson,
Hans Mallmin,
Andreas Kindmark,
Paul Gerdhem,
Mulnard,
Pfeiffer,
van Dyck,
Sano,
Jin,
Doody,
Grundman,
Thal,
Kawas,
Koss,
Cotman,
Thomas,
Gamst,
Inga Peter,
L. Adrienne Cupples,
Michael E. Mendelsohn,
Gordon S. Huggins,
David E. Housman,
Joanne M. Murabito,
Daniel Levy,
Richard H. Karas,
Alyson Kelley-Hedgepeth,
Caroline S. Fox,
LeBoff,
Wright,
Franklin,
Glowacki,
Kohlmeier,
Hurwitz,
Gao,
Choi,
Nie,
Mezei,
Priest,
Toran-Allerand,
Roberts,
Diano,
Leranth,
Bechmann,
Rao,
Gao,
Shulman,
Horvath,
Mobbs,
Etgen,
Gonz??lez-Flores,
Todd,
- Estrogen replacement therapy in patients with endometrial cancer: a survey of prescription intention of Belgian gynecologists. Rozenberg, S., Vasquez, J.B. CA: a cancer journal for clinicians. (1999)
- Estrogen receptors, breast cancer, and smoking. Daniell, H.W. N. Engl. J. Med. (1980)
- Development of lithogenic bile during puberty in Pima indians. Bennion, L.J., Knowler, W.C., Mott, D.M., Spagnola, A.M., Bennett, P.H. N. Engl. J. Med. (1979)
- Prevention of bone loss with alendronate in postmenopausal women under 60 years of age. Early Postmenopausal Intervention Cohort Study Group. Hosking, D., Chilvers, C.E., Christiansen, C., Ravn, P., Wasnich, R., Ross, P., McClung, M., Balske, A., Thompson, D., Daley, M., Yates, A.J. N. Engl. J. Med. (1998)
- Endometrial cancer and estrogen use. Report of a large case-control study. Antunes, C.M., Strolley, P.D., Rosenshein, N.B., Davies, J.L., Tonascia, J.A., Brown, C., Burnett, L., Rutledge, A., Pokempner, M., Garcia, R. N. Engl. J. Med. (1979)
- Impairment of the natriuretic peptide system in follitropin receptor knockout mice and reversal by estradiol: implications for obesity-associated hypertension in menopause. Belo, N.O., Sairam, M.R., Dos Reis, A.M. Endocrinology (2008)
- Osteoporosis in women with anorexia nervosa. Rigotti, N.A., Nussbaum, S.R., Herzog, D.B., Neer, R.M. N. Engl. J. Med. (1984)
- Vaginal stimulation: an important determinant of maternal bonding in sheep. Keverne, E.B., Levy, F., Poindron, P., Lindsay, D.R. Science (1983)
- Ejaculatory pattern in female rats without androgen treatment. Emery, D.E., Sachs, B.D. Science (1975)
- Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study. Mulnard, R.A., Cotman, C.W., Kawas, C., van Dyck, C.H., Sano, M., Doody, R., Koss, E., Pfeiffer, E., Jin, S., Gamst, A., Grundman, M., Thomas, R., Thal, L.J. JAMA (2000)
- Mechanisms controlling the function and life span of the corpus luteum. Niswender, G.D., Juengel, J.L., Silva, P.J., Rollyson, M.K., McIntush, E.W. Physiol. Rev. (2000)
- Luteolysis: a neuroendocrine-mediated event. McCracken, J.A., Custer, E.E., Lamsa, J.C. Physiol. Rev. (1999)
- Genome-wide analysis of estrogen receptor binding sites. Carroll, J.S., Meyer, C.A., Song, J., Li, W., Geistlinger, T.R., Eeckhoute, J., Brodsky, A.S., Keeton, E.K., Fertuck, K.C., Hall, G.F., Wang, Q., Bekiranov, S., Sementchenko, V., Fox, E.A., Silver, P.A., Gingeras, T.R., Liu, X.S., Brown, M. Nat. Genet. (2006)
- Time of implantation of the conceptus and loss of pregnancy. Wilcox, A.J., Baird, D.D., Weinberg, C.R. N. Engl. J. Med. (1999)
- Estrogen and progestin compared with simvastatin for hypercholesterolemia in postmenopausal women. Darling, G.M., Johns, J.A., McCloud, P.I., Davis, S.R. N. Engl. J. Med. (1997)
- Peptide antagonists of the human estrogen receptor. Norris, J.D., Paige, L.A., Christensen, D.J., Chang, C.Y., Huacani, M.R., Fan, D., Hamilton, P.T., Fowlkes, D.M., McDonnell, D.P. Science (1999)
- Estradiol shortens the period of hamster circadian rhythms. Morin, L.P., Fitzgerald, K.M., Zucker, I. Science (1977)
- Occult vitamin D deficiency in postmenopausal US women with acute hip fracture. LeBoff, M.S., Kohlmeier, L., Hurwitz, S., Franklin, J., Wright, J., Glowacki, J. JAMA (1999)
- The role of insulin-like growth factor-I and growth factor-associated signal transduction pathways in estradiol and progesterone facilitation of female reproductive behaviors. Etgen, A.M., Gonz??lez-Flores, O., Todd, B.J. Frontiers in neuroendocrinology (2006)
- Opposing effects of runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness. Chimge, N.O., Baniwal, S.K., Luo, J., Coetzee, S., Khalid, O., Berman, B.P., Tripathy, D., Ellis, M.J., Frenkel, B. Clin. Cancer Res. (2012)
- An estrogen receptor from Xenopus laevis liver possibly connected with vitellogenin synthesis. Westley, B., Knowland, J. Cell (1978)
- Editorial: Cancer risk and estrogen use in the menopause. Ryan, K.J. N. Engl. J. Med. (1975)
- Dehydroepiandrosterone sulfate loading test in the diagnosis of complicated pregnancies. Tulchinsky, D., Osathanondh, R., Finn, A. N. Engl. J. Med. (1976)
- CDK-independent activation of estrogen receptor by cyclin D1. Zwijsen, R.M., Wientjens, E., Klompmaker, R., van der Sman, J., Bernards, R., Michalides, R.J. Cell (1997)
- A secreted glycoprotein induced by estrogen in human breast cancer cell lines. Westley, B., Rochefort, H. Cell (1980)
- Effects of estrogens and progestins on the biochemistry and morphology of the postmenopausal endometrium. Whitehead, M.I., Townsend, P.T., Pryse-Davies, J., Ryder, T.A., King, R.J. N. Engl. J. Med. (1981)
- Serum suppresses the expression of hormonally induced functions in cultured granulosa cells. Orly, J., Sato, G., Erickson, G.F. Cell (1980)
- Quantitation of elongating form A and B RNA polymerases in chick oviduct nuclei and effects of estradiol. Cox, R.F. Cell (1976)
- Dexamethasone-resistant cystic fibrosis fibroblasts show cross-resistance to sex steroids. Breslow, J.L., Epstein, J., Fontaine, J.H. Cell (1978)
- Direct induction by estradiol on vitellogenin synthesis in organ cultures of male Xenopus laevis liver. Green, C.D., Tata, J.R. Cell (1976)
- The interaction of estradiol-receptor protein with the genome: an argument for the existence of undetected specific sites. Yamamoto, K., Alberts, B. Cell (1975)
- Effect of estrogen/progestin potency on lipid/lipoprotein cholesterol. Wahl, P., Walden, C., Knopp, R., Hoover, J., Wallace, R., Heiss, G., Rifkind, B. N. Engl. J. Med. (1983)
- Androgen-dependent fibrinolytic activity in a murine mammary carcinoma (Shionogi SC-115 cells) in vitro. Mak, T.W., Rutledge, G., Sutherland, D.J. Cell (1976)
- The endogenous estradiol metabolite 2-methoxyestradiol reduces atherosclerotic lesion formation in female apolipoprotein E-deficient mice. Bourghardt, J., Bergström, G., Krettek, A., Sjöberg, S., Borén, J., Tivesten, A. Endocrinology (2007)
- Chronic estradiol treatment improves brain homeostasis during aging in female rats. Alonso, A., Moreno, M., Ordóñez, P., Fernández, R., Pérez, C., Díaz, F., Navarro, A., Tolivia, J., González, C. Endocrinology (2008)
- Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals. Gao, Q., Mezei, G., Nie, Y., Rao, Y., Choi, C.S., Bechmann, I., Leranth, C., Toran-Allerand, D., Priest, C.A., Roberts, J.L., Gao, X.B., Mobbs, C., Shulman, G.I., Diano, S., Horvath, T.L. Nat. Med. (2007)
- BRCA1 inhibition of estrogen receptor signaling in transfected cells. Fan, S., Wang, J., Yuan, R., Ma, Y., Meng, Q., Erdos, M.R., Pestell, R.G., Yuan, F., Auborn, K.J., Goldberg, I.D., Rosen, E.M. Science (1999)
- AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Anzick, S.L., Kononen, J., Walker, R.L., Azorsa, D.O., Tanner, M.M., Guan, X.Y., Sauter, G., Kallioniemi, O.P., Trent, J.M., Meltzer, P.S. Science (1997)
- The impact of estradiol on bone mineral density is modulated by the specific estrogen receptor-alpha cofactor retinoblastoma-interacting zinc finger protein-1 insertion/deletion polymorphism. Grundberg, E., Akesson, K., Kindmark, A., Gerdhem, P., Holmberg, A., Mellström, D., Ljunggren, O., Orwoll, E., Mallmin, H., Ohlsson, C., Brändström, H. J. Clin. Endocrinol. Metab. (2007)
- Estradiol acts directly on bone marrow myeloid progenitors to differentially regulate GM-CSF or Flt3 ligand-mediated dendritic cell differentiation. Carreras, E., Turner, S., Paharkova-Vatchkova, V., Mao, A., Dascher, C., Kovats, S. J. Immunol. (2008)
- Variation in estrogen-related genes associated with cardiovascular phenotypes and circulating estradiol, testosterone, and dehydroepiandrosterone sulfate levels. Peter, I., Kelley-Hedgepeth, A., Fox, C.S., Cupples, L.A., Huggins, G.S., Housman, D.E., Karas, R.H., Mendelsohn, M.E., Levy, D., Murabito, J.M. J. Clin. Endocrinol. Metab. (2008)
- Relative contributions of aging and estrogen deficiency to postmenopausal bone loss. Richelson, L.S., Wahner, H.W., Melton, L.J., Riggs, B.L. N. Engl. J. Med. (1984)
- Bone mineral content of amenorrheic and eumenorrheic athletes. Drinkwater, B.L., Nilson, K., Chesnut, C.H., Bremner, W.J., Shainholtz, S., Southworth, M.B. N. Engl. J. Med. (1984)
- Vitellogenin gene expression in male Xenopus hepatocytes during primary and secondary stimulation with estrogen in cell cultures. Searle, P.F., Tata, J.R. Cell (1981)
- A randomized trial of chemotherapy and hormonal therapy in advanced breast cancer. Kiang, D.T., Gay, J., Goldman, A., Kennedy, B.J. N. Engl. J. Med. (1985)
- Transvaginal ultrasonography compared with endometrial biopsy for the detection of endometrial disease. Postmenopausal Estrogen/Progestin Interventions Trial. Langer, R.D., Pierce, J.J., O'Hanlan, K.A., Johnson, S.R., Espeland, M.A., Trabal, J.F., Barnabei, V.M., Merino, M.J., Scully, R.E. N. Engl. J. Med. (1997)