Chemical Compound Review:
1,25-DIHYDROXYCHOLECALCIFEROL (1S,5Z)-5-[(2E)-2-[(1R,7aR)- 1-(6-hydroxy-6...
Synonyms:
AC1O5HE9, 1,25-(OH)2D3, 125338-24-1, UNII-FXC9231JVH, Calcitriol [USAN:USP:INN:BAN:JAN]
- Vitamin D: recent advances. DeLuca, H.F., Schnoes, H.K. Annu. Rev. Biochem. (1983)
- Hypercalcemia and increases in serum hormone value during prolonged administration of 1alpha,25-dihydroxyvitamin D. Bell, N.H., Stern, P.H. N. Engl. J. Med. (1978)
- Response of 1alpha,25-dihydroxyvitamin D3 to hypocalcemia in human subjects. Bilezikian, J.P., Canfield, R.E., Jacobs, T.P., Polay, J.S., D'Adamo, A.P., Eisman, J.A., DeLuca, H.F. N. Engl. J. Med. (1978)
- Reduced binding of [3H]1,25-dihydroxyvitamin D3 in the parathyroid glands of patients with renal failure. Korkor, A.B. N. Engl. J. Med. (1987)
- Hereditary hypophosphatemic rickets with hypercalciuria. Tieder, M., Modai, D., Samuel, R., Arie, R., Halabe, A., Bab, I., Gabizon, D., Liberman, U.A. N. Engl. J. Med. (1985)
- Bone mineral density and anorexia nervosa in women. Salisbury, J.J., Mitchell, J.E. The American journal of psychiatry. (1991)
- Vitamin D deficiency and associated factors in adolescent girls in Beijing. Du, X., Greenfield, H., Fraser, D.R., Ge, K., Trube, A., Wang, Y. Am. J. Clin. Nutr. (2001)
- 1,25-dihydroxyvitamin D3 stimulates adipocyte differentiation in cultures of fetal rat calvaria cells: comparison with the effects of dexamethasone. Bellows, C.G., Wang, Y.H., Heersche, J.N., Aubin, J.E. Endocrinology (1994)
- Light, vitamin D and psychiatry. Role of 1,25 dihydroxyvitamin D3 (soltriol) in etiology and therapy of seasonal affective disorder and other mental processes. Stumpf, W.E., Privette, T.H. Psychopharmacology (Berl.) (1989)
- Calcium dynamics: a model system approach. Hurwitz, S., Fishman, S., Talpaz, H. J. Nutr. (1987)
- Calcium: taste, intake, and appetite. Tordoff, M.G. Physiol. Rev. (2001)
- Current understanding of the molecular actions of vitamin D. Jones, G., Strugnell, S.A., DeLuca, H.F. Physiol. Rev. (1998)
- Inactivating mutations in the 25-hydroxyvitamin D3 1alpha-hydroxylase gene in patients with pseudovitamin D-deficiency rickets. Kitanaka, S., Takeyama, K., Murayama, A., Sato, T., Okumura, K., Nogami, M., Hasegawa, Y., Niimi, H., Yanagisawa, J., Tanaka, T., Kato, S. N. Engl. J. Med. (1998)
- "Idiopathic" hypercalciuria and hereditary hypophosphatemic rickets. Two phenotypical expressions of a common genetic defect. Tieder, M., Modai, D., Shaked, U., Samuel, R., Arie, R., Halabe, A., Maor, J., Weissgarten, J., Averbukh, Z., Cohen, N. N. Engl. J. Med. (1987)
- 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol: conversion impaired by systemic metabolic acidosis. Lee, S.W., Russell, J., Avioli, L.V. Science (1977)
- Fat-soluble vitamin nutriture in primary biliary cirrhosis. Kaplan, M.M., Elta, G.H., Furie, B., Sadowski, J.A., Russell, R.M. Gastroenterology (1988)
- Metabolites of vitamin D in human vitamin-D deficiency: effect of vitamin D3 or 1,25-dihydroxycholecalciferol. Papapoulos, S.E., Clemens, T.L., Fraher, L.J., Gleed, J., O'Riordan, J.L. Lancet (1980)
- The pathogenesis of humoral hypercalcaemia of malignancy. Ralston, S.H. Lancet (1987)
- Vitamin D and pregnancy: the maternal-fetal metabolism of vitamin D. Gray, T.K., Lowe, W., Lester, G.E. Endocr. Rev. (1981)
- Dynamic changes in circulating 1,25-dihydroxyvitamin D during reproduction in rats. Pike, J.W., Parker, J.B., Haussler, M.R., Boass, A., Toverud, S.V. Science (1979)
- Adequate response of plasma 1,25-dihydroxyvitamin D to parturition in paretic (milk fever) dairy cows. Horst, R.L., Eisman, J.A., Jorgensen, N.A., DeLuca, H.F. Science (1977)
- 1,25-Dihydroxyvitamin D in biological fluids: a simplified and sensitive assay. Eisman, J.A., Hamstra, A.J., Kream, B.E., DeLuca, H.F. Science (1976)
- A cellular defect in hereditary vitamin-D-dependent rickets type II: defective nuclear uptake of 1,25-dihydroxyvitamin D in cultured skin fibroblasts. Eil, C., Liberman, U.A., Rosen, J.F., Marx, S.J. N. Engl. J. Med. (1981)
- 1,25-Dihydroxycholecalciferol stimulation of a mitochondrial protein in chick intestinal cells. Hobden, A.N., Harding, M., Lawson, D.E. Nature (1980)
- 1,25-dihydroxycholecalciferol and parathormone: effects on isolated osteoclast-like and osteoblast-like cells. Wong, G.L., Luben, R.A., Cohn, D.V. Science (1977)
- Regulation of serum 1alpha,25-dihydroxyvitamin D3 by calcium and phosphate in the rat. Hughes, M.R., Brumbaugh, P.F., Hussler, M.R., Wergedal, J.E., Baylink, D.J. Science (1975)
- Calcium homeostasis in immobilization: an example of resorptive hypercalciuria. Stewart, A.F., Adler, M., Byers, C.M., Segre, G.V., Broadus, A.E. N. Engl. J. Med. (1982)
- Elevated parathyroid hormone-related peptide associated with lactation and bone density loss. Sowers, M.F., Hollis, B.W., Shapiro, B., Randolph, J., Janney, C.A., Zhang, D., Schork, A., Crutchfield, M., Stanczyk, F., Russell-Aulet, M. JAMA (1996)
- Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation. Udagawa, N., Horwood, N.J., Elliott, J., Mackay, A., Owens, J., Okamura, H., Kurimoto, M., Chambers, T.J., Martin, T.J., Gillespie, M.T. J. Exp. Med. (1997)
- IL-1-induced murine osteoblast IL-6 production is mediated by the type 1 IL-1 receptor and is increased by 1,25 dihydroxyvitamin D3. Lacey, D.L., Grosso, L.E., Moser, S.A., Erdmann, J., Tan, H.L., Pacifici, R., Villareal, D.T. J. Clin. Invest. (1993)
- Lipopolysaccharide (LPS) partial structures inhibit responses to LPS in a human macrophage cell line without inhibiting LPS uptake by a CD14-mediated pathway. Kitchens, R.L., Ulevitch, R.J., Munford, R.S. J. Exp. Med. (1992)
- Interferon gamma drastically modifies the regulation of interleukin 1 genes by endotoxin in U937 cells. Ucla, C., Roux-Lombard, P., Fey, S., Dayer, J.M., Mach, B. J. Clin. Invest. (1990)
- Posttranscriptional stabilization underlies p53-independent induction of p21WAF1/CIP1/SDI1 in differentiating human leukemic cells. Schwaller, J., Koeffler, H.P., Niklaus, G., Loetscher, P., Nagel, S., Fey, M.F., Tobler, A. J. Clin. Invest. (1995)
- Molecular cloning of matrix Gla protein: implications for substrate recognition by the vitamin K-dependent gamma-carboxylase. Price, P.A., Fraser, J.D., Metz-Virca, G. Proc. Natl. Acad. Sci. U.S.A. (1987)
- Potentiation of lipopolysaccharide-induced tumor necrosis factor-alpha expression by 1,25-dihydroxyvitamin D3. Prehn, J.L., Fagan, D.L., Jordan, S.C., Adams, J.S. Blood (1992)
- 1-alpha-hydroxyvitamin D3 in chronic renal failure. A potent analogue of the kidney hormone, 1,25-dihydroxycholecalciferol. Chan, J.C., Oldham, S.B., Holick, M.F., DeLuca, H.F. JAMA (1975)
- The noncalcemic analogue of vitamin D, 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion. Brown, A.J., Ritter, C.R., Finch, J.L., Morrissey, J., Martin, K.J., Murayama, E., Nishii, Y., Slatopolsky, E. J. Clin. Invest. (1989)
- Oral intake of phosphorus can determine the serum concentration of 1,25-dihydroxyvitamin D by determining its production rate in humans. Portale, A.A., Halloran, B.P., Murphy, M.M., Morris, R.C. J. Clin. Invest. (1986)