The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

IPTG     (2R,3R,4S,5R,6S)-2- (hydroxymethyl)-6...

Synonyms: PubChem9901, AC1LCVOH, SureCN25476, ARK037, CHEBI:61448, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of ISOPROPYL THIOGALACTOSIDE

 

High impact information on ISOPROPYL THIOGALACTOSIDE

 

Chemical compound and disease context of ISOPROPYL THIOGALACTOSIDE

 

Biological context of ISOPROPYL THIOGALACTOSIDE

 

Anatomical context of ISOPROPYL THIOGALACTOSIDE

 

Associations of ISOPROPYL THIOGALACTOSIDE with other chemical compounds

  • In medium containing methotrexate but no IPTG, the clones were unable to grow in soft agar, indicating that methotrexate resistance due to gene amplification is separable from transformation [26].
  • Following transcriptional induction with IPTG or galactose, subcellular fractions were prepared and analyzed immunochemically and catalytically [27].
  • In the absence of an inducer (allolactose or IPTG) this strain, DH1 lackan , cannot grow on kanamycin-containing media due to the repression of kan expression by LacI protein binding to lac O/P [28].
  • Nutrient starvation experiments and the use of relA spoT mutant strains, IPTG-regulated overproduction of ppGpp and lacZ fusions revealed that the stringent response alarmone guanosine 3',5'-bispyrophosphate (ppGpp) is the main positive effector of Cka synthesis [29].
  • In contrast, in these cells, IPTG-dependent induction of p14ARF, which sequesters MDM2 away from p53, does not lead to detectable phosphorylation of any of the five N-terminal serine residues tested (6, 9, 15, 20, 37) [30].
 

Gene context of ISOPROPYL THIOGALACTOSIDE

 

Analytical, diagnostic and therapeutic context of ISOPROPYL THIOGALACTOSIDE

References

  1. Crystal structure of lac repressor core tetramer and its implications for DNA looping. Friedman, A.M., Fischmann, T.O., Steitz, T.A. Science (1995) [Pubmed]
  2. FtsZ in Bacillus subtilis is required for vegetative septation and for asymmetric septation during sporulation. Beall, B., Lutkenhaus, J. Genes Dev. (1991) [Pubmed]
  3. High-level expression of an interferon alpha 2 gene cloned in phage M13mp7 and subsequent purification with a monoclonal antibody. Slocombe, P., Easton, A., Boseley, P., Burke, D.C. Proc. Natl. Acad. Sci. U.S.A. (1982) [Pubmed]
  4. Organization and nucleotide sequence determination of a gene cluster involved in 3-chlorocatechol degradation. Frantz, B., Chakrabarty, A.M. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  5. Widespread use of the glu-tRNAGln transamidation pathway among bacteria. A member of the alpha purple bacteria lacks glutaminyl-trna synthetase. Gagnon, Y., Lacoste, L., Champagne, N., Lapointe, J. J. Biol. Chem. (1996) [Pubmed]
  6. Development of genetic circuitry exhibiting toggle switch or oscillatory behavior in Escherichia coli. Atkinson, M.R., Savageau, M.A., Myers, J.T., Ninfa, A.J. Cell (2003) [Pubmed]
  7. The DnaA protein determines the initiation mass of Escherichia coli K-12. Løbner-Olesen, A., Skarstad, K., Hansen, F.G., von Meyenburg, K., Boye, E. Cell (1989) [Pubmed]
  8. Stringent regulation of stably integrated chloramphenicol acetyl transferase genes by E. coli lac repressor in monkey cells. Figge, J., Wright, C., Collins, C.J., Roberts, T.M., Livingston, D.M. Cell (1988) [Pubmed]
  9. lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells. Brown, M., Figge, J., Hansen, U., Wright, C., Jeang, K.T., Khoury, G., Livingston, D.M., Roberts, T.M. Cell (1987) [Pubmed]
  10. The lac operator-repressor system is functional in the mouse. Cronin, C.A., Gluba, W., Scrable, H. Genes Dev. (2001) [Pubmed]
  11. Toluene degradation by Pseudomonas putida F1. Nucleotide sequence of the todC1C2BADE genes and their expression in Escherichia coli. Zylstra, G.J., Gibson, D.T. J. Biol. Chem. (1989) [Pubmed]
  12. Benefit of transcription-coupled nucleotide excision repair for gene expression in u.v.-damaged Escherichia coli. Li, B.H., Bockrath, R. Mol. Microbiol. (1995) [Pubmed]
  13. Analysis of a bacterial hygromycin B resistance gene by transcriptional and translational fusions and by DNA sequencing. Kaster, K.R., Burgett, S.G., Rao, R.N., Ingolia, T.D. Nucleic Acids Res. (1983) [Pubmed]
  14. Expression, mutagenesis, and characterization of recombinant low-potential cytochrome c550 of photosystem II. Andrews, H., Li, Z., Altuve-Blanco, A., Rivera, M., Burnap, R.L. Biochemistry (2005) [Pubmed]
  15. Cytochrome P450 4A4: expression in Escherichia coli, purification, and characterization of catalytic properties. Nishimoto, M., Clark, J.E., Masters, B.S. Biochemistry (1993) [Pubmed]
  16. RNA polymerase II transcription blocked by Escherichia coli lac repressor. Deuschle, U., Hipskind, R.A., Bujard, H. Science (1990) [Pubmed]
  17. CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein. Timchenko, N.A., Wilde, M., Nakanishi, M., Smith, J.R., Darlington, G.J. Genes Dev. (1996) [Pubmed]
  18. T7 RNA polymerase directed expression of the Escherichia coli rrnB operon. Steen, R., Dahlberg, A.E., Lade, B.N., Studier, F.W., Dunn, J.J. EMBO J. (1986) [Pubmed]
  19. A novel outer membrane lipoprotein, LolB (HemM), involved in the LolA (p20)-dependent localization of lipoproteins to the outer membrane of Escherichia coli. Matsuyama, S., Yokota, N., Tokuda, H. EMBO J. (1997) [Pubmed]
  20. Detailed map of a cis-regulatory input function. Setty, Y., Mayo, A.E., Surette, M.G., Alon, U. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  21. Control of gene expression in tobacco cells using a bacterial operator-repressor system. Wilde, R.J., Shufflebottom, D., Cooke, S., Jasinska, I., Merryweather, A., Beri, R., Brammar, W.J., Bevan, M., Schuch, W. EMBO J. (1992) [Pubmed]
  22. Cytochemical observation of regulated bacterial beta-galactosidase gene expression in mammalian cells. Liu, H.S., Feliciano, E.S., Stambrook, P.J. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  23. A mutant p53 protein is required for maintenance of the transformed phenotype in cells transformed with p53 plus ras cDNAs. Zambetti, G.P., Olson, D., Labow, M., Levine, A.J. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  24. Role of calpain in skeletal-muscle protein degradation. Huang, J., Forsberg, N.E. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  25. Mitochondrial antisense RNA for cytochrome C oxidase (MARCO) can induce morphologic changes and cell death in human hematopoietic cell lines. Shirafuji, N., Takahashi, S., Matsuda, S., Asano, S. Blood (1997) [Pubmed]
  26. Increased methotrexate resistance and dhfr gene amplification as a consequence of induced Ha-ras expression in NIH 3T3 cells. Wani, M.A., Xu, X., Stambrook, P.J. Cancer Res. (1994) [Pubmed]
  27. Functional characterization of flavin-containing monooxygenase 1B1 expressed in Saccharomyces cerevisiae and Escherichia coli and analysis of proposed FAD- and membrane-binding domains. Lawton, M.P., Philpot, R.M. J. Biol. Chem. (1993) [Pubmed]
  28. Repressor titration: a novel system for selection and stable maintenance of recombinant plasmids. Williams, S.G., Cranenburgh, R.M., Weiss, A.M., Wrighton, C.J., Sherratt, D.J., Hanak, J.A. Nucleic Acids Res. (1998) [Pubmed]
  29. Codon-usage based regulation of colicin K synthesis by the stress alarmone ppGpp. Kuhar, I., van Putten, J.P., Zgur-Bertok, D., Gaastra, W., Jordi, B.J. Mol. Microbiol. (2001) [Pubmed]
  30. Limited role of N-terminal phosphoserine residues in the activation of transcription by p53. Jackson, M.W., Agarwal, M.K., Agarwal, M.L., Agarwal, A., Stanhope-Baker, P., Williams, B.R., Stark, G.R. Oncogene (2004) [Pubmed]
  31. The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle. Denko, N.C., Giaccia, A.J., Stringer, J.R., Stambrook, P.J. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
  32. Reconstitution of the GTP-dependent adenylate cyclase from products of the yeast CYR1 and RAS2 genes in Escherichia coli. Uno, I., Mitsuzawa, H., Matsumoto, K., Tanaka, K., Oshima, T., Ishikawa, T. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  33. Cell transformation by c-fos requires an extended period of expression and is independent of the cell cycle. Miao, G.G., Curran, T. Mol. Cell. Biol. (1994) [Pubmed]
  34. Expression of the serum- and glucocorticoid-inducible protein kinase, Sgk, is a cell survival response to multiple types of environmental stress stimuli in mammary epithelial cells. Leong, M.L., Maiyar, A.C., Kim, B., O'Keeffe, B.A., Firestone, G.L. J. Biol. Chem. (2003) [Pubmed]
  35. Functional Domains of Human Tryptophan Hydroxylase 2 (hTPH2). Carkaci-Salli, N., Flanagan, J.M., Martz, M.K., Salli, U., Walther, D.J., Bader, M., Vrana, K.E. J. Biol. Chem. (2006) [Pubmed]
  36. Occludin is a functional component of the tight junction. McCarthy, K.M., Skare, I.B., Stankewich, M.C., Furuse, M., Tsukita, S., Rogers, R.A., Lynch, R.D., Schneeberger, E.E. J. Cell. Sci. (1996) [Pubmed]
  37. Detection of induced beta-galactosidase activity in individual non-culturable cells of pathogenic bacteria by quantitative cytological assay. Nwoguh, C.E., Harwood, C.R., Barer, M.R. Mol. Microbiol. (1995) [Pubmed]
  38. DNA packaging mutant: repression of the vaccinia virus A32 gene results in noninfectious, DNA-deficient, spherical, enveloped particles. Cassetti, M.C., Merchlinsky, M., Wolffe, E.J., Weisberg, A.S., Moss, B. J. Virol. (1998) [Pubmed]
  39. Vaccinia virus morphogenesis is interrupted when expression of the gene encoding an 11-kilodalton phosphorylated protein is prevented by the Escherichia coli lac repressor. Zhang, Y.F., Moss, B. J. Virol. (1991) [Pubmed]
 
WikiGenes - Universities