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Chemical Compound Review

Emitefur     [3-cyano-6- (phenylcarbonyloxy)pyridin- 2...

Synonyms: Last-F, BOF-A2, Emitefur [INN], SureCN27921, Bof A2, ...
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Disease relevance of Emitefur


High impact information on Emitefur


  1. Phase I assessment of the pharmacokinetics, metabolism, and safety of emitefur in patients with refractory solid tumors. Nemunaitis, J., Eager, R., Twaddell, T., Corey, A., Sekar, K., Tkaczuk, K., Thompson, J., Hoff, P.M., Pazdur, R. J. Clin. Oncol. (2000) [Pubmed]
  2. Antitumor activity of BOF-A2, a new 5-fluorouracil derivative. Fujii, S., Fukushima, M., Shimamoto, Y., Ohshimo, H., Imaoka, T., Shirasaka, T. Jpn. J. Cancer Res. (1989) [Pubmed]
  3. Efficacy of a new 5-fluorouracil derivative, BOF-A2, in advanced non-small cell lung cancer. A multi-center phase II study. Nakai, Y., Furuse, K., Ohta, M., Yamaguchi, Y., Fujii, M., Asakawa, M., Fukuoka, M., Yoshida, K., Niitani, H. Acta oncologica (Stockholm, Sweden) (1994) [Pubmed]
  4. The inhibitory action of BOF-A2, a 5-fluorouracil derivative, on squamous cell carcinoma. Yoneda, K., Yamamoto, T., Ueta, E., Osaki, T. Cancer Lett. (1999) [Pubmed]
  5. A phase II trial of a new 5-fluorouracil derivative, BOF-A2 (Emitefur), for patients with advanced gastric cancer. Sugimachi, K., Maehara, Y. Surgery today. (2000) [Pubmed]
  6. Oral administration of BOF-A2 to rats with lung transplanted tumors results in increased 5-fluorouracil levels. Miyauchi, S., Imaoka, T., Utsunomiya, T., Hayashi, K., Kubo, M., Kawaguchi, T., Matsui, Y. Jpn. J. Cancer Res. (1994) [Pubmed]
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