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Chemical Compound Review

Hmb-d6     3-hydroxy-3-methyl-butanoic acid

Synonyms: PubChem6288, ACMC-1B512, AG-B-97194, AG-L-65131, CHEBI:37084, ...
 
 
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Disease relevance of Hmb-d6

 

High impact information on Hmb-d6

 

Chemical compound and disease context of Hmb-d6

 

Biological context of Hmb-d6

 

Anatomical context of Hmb-d6

 

Associations of Hmb-d6 with other chemical compounds

 

Gene context of Hmb-d6

 

Analytical, diagnostic and therapeutic context of Hmb-d6

References

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  2. Clinical and metabolic abnormalities in a boy with dietary deficiency of biotin. Sweetman, L., Surh, L., Baker, H., Peterson, R.M., Nyhan, W.L. Pediatrics (1981) [Pubmed]
  3. Beta-methylcrotonic aciduria associated with lactic acidosis. Roth, K., Cohn, R., Yandrasitz, J., Preti, G., Dodd, P., Segal, S. J. Pediatr. (1976) [Pubmed]
  4. Beta-hydroxy-beta-methylbutyrate supplementation in critically ill trauma patients. Kuhls, D.A., Rathmacher, J.A., Musngi, M.D., Frisch, D.A., Nielson, J., Barber, A., MacIntyre, A.D., Coates, J.E., Fildes, J.J. The Journal of trauma (2007) [Pubmed]
  5. Increased urinary excretion of beta-hydroxyisovaleric acid in ketotic and non-ketotic type II diabetes mellitus. Yu, W.M., Kuhara, T., Inoue, Y., Matsumoto, I., Iwasaki, R., Morimoto, S. Clin. Chim. Acta (1990) [Pubmed]
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  9. Body composition in 70-year-old adults responds to dietary beta-hydroxy-beta-methylbutyrate similarly to that of young adults. Vukovich, M.D., Stubbs, N.B., Bohlken, R.M. J. Nutr. (2001) [Pubmed]
  10. Nutritional treatment for acquired immunodeficiency virus-associated wasting using beta-hydroxy beta-methylbutyrate, glutamine, and arginine: a randomized, double-blind, placebo-controlled study. Clark, R.H., Feleke, G., Din, M., Yasmin, T., Singh, G., Khan, F.A., Rathmacher, J.A. JPEN. Journal of parenteral and enteral nutrition. (2000) [Pubmed]
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  13. In vitro effects of beta-hydroxy-beta-methylbutyrate (HMB) on cell-mediated immunity in fish. Siwicki, A.K., Fuller, J.C., Nissen, S., Ostaszewski, P., Studnicka, M. Vet. Immunol. Immunopathol. (2000) [Pubmed]
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  18. Prenatal diagnosis of isovaleric acidaemia by enzyme and metabolite assay in the first and second trimesters. Kleijer, W.J., van der Kraan, M., Huijmans, J.G., van den Heuvel, C.M., Jakobs, C. Prenat. Diagn. (1995) [Pubmed]
  19. Influence of HMB (beta-hydroxy-beta-methylbutyrate) on antibody secreting cells (ASC) after in vitro and in vivo immunization with the anti-Yersinia ruckeri vaccine of rainbow trout (Oncorhynchus mykiss). Siwicki, A.K., Morand, M., Fuller, J.C., Nissen, S., Kazun, K., Glombski, E. Vet. Res. (2001) [Pubmed]
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  21. Effect of leucine metabolite beta-hydroxy-beta-methylbutyrate on muscle metabolism during resistance-exercise training. Nissen, S., Sharp, R., Ray, M., Rathmacher, J.A., Rice, D., Fuller, J.C., Connelly, A.S., Abumrad, N. J. Appl. Physiol. (1996) [Pubmed]
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  23. Isolated biotin-resistant 3-methylcrotonyl-CoA carboxylase deficiency: long-term outcome in a case with neonatal onset. Lehnert, W., Niederhoff, H., Suormala, T., Baumgartner, E.R. Eur. J. Pediatr. (1996) [Pubmed]
  24. Acylcarnitine profile in tissues and body fluids of biotin-deficient rats with and without L-carnitine supplementation. Shigematsu, Y., Bykov, I.L., Liu, Y.Y., Nakai, A., Kikawa, Y., Sudo, M., Fujioka, M. J. Inherit. Metab. Dis. (1994) [Pubmed]
  25. The ubiquitin-proteasome pathway as a therapeutic target for muscle wasting. Tisdale, M.J. The journal of supportive oncology. (2005) [Pubmed]
  26. Beta-hydroxy-beta-methylbutyrate ingestion, Part I: effects on strength and fat free mass. Gallagher, P.M., Carrithers, J.A., Godard, M.P., Schulze, K.E., Trappe, S.W. Medicine and science in sports and exercise. (2000) [Pubmed]
  27. Popular sports supplements and ergogenic aids. Juhn, M. Sports medicine (Auckland, N.Z.) (2003) [Pubmed]
  28. Anti-inflammatory and anticatabolic effects of short-term beta-hydroxy-beta-methylbutyrate supplementation on chronic obstructive pulmonary disease patients in intensive care unit. Hsieh, L.C., Chien, S.L., Huang, M.S., Tseng, H.F., Chang, C.K. Asia Pacific journal of clinical nutrition. (2006) [Pubmed]
  29. Beta-hydroxy-beta-methylbutyrate (HMB) supplementation does not affect changes in strength or body composition during resistance training in trained men. Slater, G., Jenkins, D., Logan, P., Lee, H., Vukovich, M., Rathmacher, J.A., Hahn, A.G. International journal of sport nutrition and exercise metabolism. (2001) [Pubmed]
  30. Fungal metabolic model for 3-methylcrotonyl-CoA carboxylase deficiency. Rodríguez, J.M., Ruíz-Sala, P., Ugarte, M., Peñalva, M.A. J. Biol. Chem. (2004) [Pubmed]
 
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