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Chemical Compound Review

Alcohols     ethanol

Synonyms: Aethanol, Anhydrol, ethyl alcohol, grain alcohol, Alcohol, Grain, ...
 
 
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Disease relevance of ethanol

 

Psychiatry related information on ethanol

 

High impact information on ethanol

 

Chemical compound and disease context of ethanol

 

Biological context of ethanol

 

Anatomical context of ethanol

  • CONCLUSIONS: Alcohol does not itself evoke an increase in [Ca2+]i in hepatocytes cultured on matrigel but perturbs receptor-operated [Ca2+]i signaling [28].
  • Letter: Alcohol and cancer of breast and thyroid [29].
  • CONCLUSIONS: Alcohol consumption induces an increase of natural killer T cells in the liver and a high sensitivity of hepatocytes to cell-mediated lysis [30].
  • Pepto-Bismol liquid (primary active constituent, bismuth subsalicy-late) protected the gastric mucosa of rats against the formation of hemorrhagic lesions or erosions in response to cold + restraint stress, to a combination of aspirin and cold + restraint stress, and to ethyl alcohol [31].
  • Recent findings have also revealed that the NH2-terminal domain of ezrin is associated with the plasma membrane and the COOH-terminal domain with the cytoskeleton (Algrain, M., O. Turunen, A. Vaheri, D. Louvard, and M. Arpin. 1993. J. Cell Biol. 120: 129-139) [32].
 

Associations of ethanol with other chemical compounds

 

Gene context of ethanol

  • Because of its exclusive sensitivity to environmental alcohol, the protein was called Asr1p for Alcohol Sensitive Ring/PHD finger 1 protein [43].
  • CONCLUSIONS: Alcohol-induced liver damage is associated with a generalized induction of CYP2A6, CYP2E1 and CYP3A4 and generation of acetaldehyde and lipid peroxidation-derived protein-aldehyde adducts [44].
  • XRCC1, XRCC3, and XPD Polymorphisms as Modifiers of the Effect of Smoking and Alcohol on Colorectal Adenoma Risk [45].
  • BACKGROUND: Alcohol (EtOH) alters the plasma and tissue content of insulin-like growth factor (IGF)-I, an important anabolic hormone [46].
  • Mucosal damage produced by 150 mmol/L HCl and 60% ethyl alcohol did not increase COX-1 mRNA expression in any age group [47].
  • VL-17A cells overexpressing superoxide dismutase-3 and catalase, treatment with a tyrosine kinase inhibitor, or incubation of the cells with PKCdelta small interference RNAs significantly inhibited the ethanol-induced MKP-1 degradation and apoptosis [48].
  • The serum alanine aminotransferase (ALT) level in the Aldh2-/- mice clearly decreased upon ethanol feeding, in contrast to Aldh2+/+ mice, in which the ALT level was unchanged [49].
 

Analytical, diagnostic and therapeutic context of ethanol

References

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