Chemical Compound Review:
Chinolin quinoline
Synonyms:
Quinolin, Chinoline, QUINOLINE, benzazine, Chinoleine, ...
- Quinoline: conversion to a mutagen by human and rodent liver. Hollstein, M., Talcott, R., Wei, E. J. Natl. Cancer Inst. (1978)
- Carcinogenic activity of quinoline on rat liver. Hirao, K., Shinohara, Y., Tsuda, H., Fukushima, S., Takahashi, M. Cancer Res. (1976)
- Increased expression of nucleoside diphosphate kinase/nm23 and c-Ha-ras mRNA is associated with spontaneous lung metastasis in rat-transplantable osteosarcomas. Honoki, K., Tsutsumi, M., Miyauchi, Y., Mii, Y., Tsujiuchi, T., Morishita, T., Miura, S., Aoki, M., Kobayashi, E., Tamai, S. Cancer Res. (1993)
- Effects of T-82, a novel acetylcholinesterase inhibitor, on impaired learning and memory in passive avoidance task in rats. Isomae, K., Morimoto, S., Hasegawa, H., Morita, K., Kamei, J. Eur. J. Pharmacol. (2003)
- Synthesis and muscarinic activity of a series of quinolines and naphthalenes with a 1-azabicyclo[3.3.0]octane moiety. Suzuki, T., Usui, T., Oka, M., Suzuki, T., Kataoka, T. Chem. Pharm. Bull. (1998)
- Linomide prevents the lethal effect of anti-Fas antibody and reduces Fas-mediated ceramide production in mouse hepatocytes. Redondo, C., Flores, I., Gonzalez, A., Nagata, S., Carrera, A.C., Merida, I., Martinez-A, C. J. Clin. Invest. (1996)
- From mechanistic studies on artemisinin derivatives to new modular antimalarial drugs. Robert, A., Dechy-Cabaret, O., Cazelles, J., Meunier, B. Acc. Chem. Res. (2002)
- Intramolecular relationships in cholinesterases revealed by oocyte expression of site-directed and natural variants of human BCHE. Neville, L.F., Gnatt, A., Loewenstein, Y., Seidman, S., Ehrlich, G., Soreq, H. EMBO J. (1992)
- Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands. Riou, J.F., Guittat, L., Mailliet, P., Laoui, A., Renou, E., Petitgenet, O., Mégnin-Chanet, F., Hélène, C., Mergny, J.L. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Cloning, expression, and sequence analysis of the three genes encoding quinoline 2-oxidoreductase, a molybdenum-containing hydroxylase from Pseudomonas putida 86. Bläse, M., Bruntner, C., Tshisuaka, B., Fetzner, S., Lingens, F. J. Biol. Chem. (1996)
- The quinoline U-78036 is a potent inhibitor of HIV-1 reverse transcriptase. Althaus, I.W., Gonzales, A.J., Chou, J.J., Romero, D.L., Deibel, M.R., Chou, K.C., Kezdy, F.J., Resnick, L., Busso, M.E., So, A.G. J. Biol. Chem. (1993)
- Mefloquine, an antimalaria drug with antiprion activity in vitro, lacks activity in vivo. Kocisko, D.A., Caughey, B. J. Virol. (2006)
- Xenobiotic reductase A in the degradation of quinoline by Pseudomonas putida 86: physiological function, structure and mechanism of 8-hydroxycoumarin reduction. Griese, J.J., P Jakob, R., Schwarzinger, S., Dobbek, H. J. Mol. Biol. (2006)
- Quinoline derivatives are therapeutic candidates for transmissible spongiform encephalopathies. Murakami-Kubo, I., Doh-Ura, K., Ishikawa, K., Kawatake, S., Sasaki, K., Kira, J., Ohta, S., Iwaki, T. J. Virol. (2004)
- Specificity of rabbit cytochrome P-450 isozymes involved in the metabolic activation of the food derived mutagen 2-amino-3-methylimidazo[4,5-f] quinoline. McManus, M.E., Burgess, W., Snyderwine, E., Stupans, I. Cancer Res. (1988)
- Localization of CYP1A1 and CYP1A2 messenger RNA in normal human liver and in hepatocellular carcinoma by in situ hybridization. McKinnon, R.A., Hall, P.D., Quattrochi, L.C., Tukey, R.H., McManus, M.E. Hepatology (1991)
- Instability of microsatellites in rat colon tumors induced by heterocyclic amines. Canzian, F., Ushijima, T., Serikawa, T., Wakabayashi, K., Sugimura, T., Nagao, M. Cancer Res. (1994)
- Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNA. Wang, X., Mader, M.M., Toth, J.E., Yu, X., Jin, N., Campbell, R.M., Smallwood, J.K., Christe, M.E., Chatterjee, A., Goodson, T., Vlahos, C.J., Matter, W.F., Bloem, L.J. J. Biol. Chem. (2005)
- A common mechanism for blockade of heme polymerization by antimalarial quinolines. Sullivan, D.J., Matile, H., Ridley, R.G., Goldberg, D.E. J. Biol. Chem. (1998)
- On the molecular mechanism of chloroquine's antimalarial action. Sullivan, D.J., Gluzman, I.Y., Russell, D.G., Goldberg, D.E. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Pharmacokinetics of gyrase inhibitors, Part 1: Basic chemistry and gastrointestinal disposition. Sörgel, F., Kinzig, M. Am. J. Med. (1993)
- 5-Lipoxygenase-activating protein is the target of a quinoline class of leukotriene synthesis inhibitors. Evans, J.F., Lévillé, C., Mancini, J.A., Prasit, P., Thérien, M., Zamboni, R., Gauthier, J.Y., Fortin, R., Charleson, P., MacIntyre, D.E. Mol. Pharmacol. (1991)
- Genotoxicity of fluoroquinolines and methylquinolines. LaVoie, E.J., Defauw, J., Fealy, M., Way, B.M., McQueen, C.A. Carcinogenesis (1991)
- Synthesis and antitumor properties of N-[2-(dimethylamino)ethyl]carboxamide derivatives of fused tetracyclic quinolines and quinoxalines: a new class of putative topoisomerase inhibitors. Deady, L.W., Kaye, A.J., Finlay, G.J., Baguley, B.C., Denny, W.A. J. Med. Chem. (1997)
- Xanthurenic acid 8-O-beta-D-glucoside, a novel tryptophan metabolite in eye-color mutants of Drosophila melanogaster. Ferré, J., Real, M.D., Ménsua, J.L., Jacobson, K.B. J. Biol. Chem. (1985)
- Intracellular pH of stimulated thymocytes measured with a new fluorescent indicator. Rogers, J., Hesketh, T.R., Smith, G.A., Metcalfe, J.C. J. Biol. Chem. (1983)
- Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance. Bray, P.G., Martin, R.E., Tilley, L., Ward, S.A., Kirk, K., Fidock, D.A. Mol. Microbiol. (2005)
- Origins of enantioselectivity in reductions of ketones on cinchona alkaloid modified platinum. Vayner, G., Houk, K.N., Sun, Y.K. J. Am. Chem. Soc. (2004)
- Discovery of novel targets of quinoline drugs in the human purine binding proteome. Graves, P.R., Kwiek, J.J., Fadden, P., Ray, R., Hardeman, K., Coley, A.M., Foley, M., Haystead, T.A. Mol. Pharmacol. (2002)
- Reversal of MRP-mediated doxorubicin resistance with quinoline-based drugs. Vezmar, M., Georges, E. Biochem. Pharmacol. (2000)
- Novel target genes of the yeast regulator Pdr1p: a contribution of the TPO1 gene in resistance to quinidine and other drugs. do Valle Matta, M.A., Jonniaux, J.L., Balzi, E., Goffeau, A., van den Hazel, B. Gene (2001)
- Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model. Martirosyan, A.R., Rahim-Bata, R., Freeman, A.B., Clarke, C.D., Howard, R.L., Strobl, J.S. Biochem. Pharmacol. (2004)
- A novel quinoline derivative, MS-209, overcomes drug resistance of human lung cancer cells expressing the multidrug resistance-associated protein (MRP) gene. Narasaki, F., Oka, M., Fukuda, M., Nakano, R., Ikeda, K., Takatani, H., Terashi, K., Soda, H., Yano, O., Nakamura, T., Doyle, L.A., Tsuruo, T., Kohno, S. Cancer Chemother. Pharmacol. (1997)
- A new quinoline derivative MS-209 reverses multidrug resistance and inhibits multiorgan metastases by P-glycoprotein-expressing human small cell lung cancer cells. Nokihara, H., Yano, S., Nishioka, Y., Hanibuchi, M., Higasida, T., Tsuruo, T., Sone, S. Jpn. J. Cancer Res. (2001)
- Prevention of lethal acute graft-versus-host disease in mice by oral administration of T helper 1 inhibitor, TAK-603. Lu, Y., Sakamaki, S., Kuroda, H., Kusakabe, T., Konuma, Y., Akiyama, T., Fujimi, A., Takemoto, N., Nishiie, K., Matsunaga, T., Hirayama, Y., Kato, J., Kon, S., Kogawa, K., Niitsu, Y. Blood (2001)
- MS-209, a quinoline-type reversal agent, potentiates antitumor efficacy of docetaxel in multidrug-resistant solid tumor xenograft models. Naito, M., Matsuba, Y., Sato, S., Hirata, H., Tsuruo, T. Clin. Cancer Res. (2002)
- On the metabolism of quinoline and isoquinoline: possible molecular basis for differences in biological activities. La Voie, E.J., Adams, E.A., Shigematsu, A., Hoffmann, D. Carcinogenesis (1983)
- Studies on disease-modifying antirheumatic drugs: synthesis of novel quinoline and quinazoline derivatives and their anti-inflammatory effect. Baba, A., Kawamura, N., Makino, H., Ohta, Y., Taketomi, S., Sohda, T. J. Med. Chem. (1996)
- The structural basis of camptothecin interactions with human serum albumin: impact on drug stability. Burke, T.G., Mi, Z. J. Med. Chem. (1994)