Chemical Compound Review:
glycine 2-aminoethanoic acid
Synonyms:
Glycinum, Aciport, Amitone, Corilin, Glicina, ...
Rees,
van den Maagdenberg,
Stephenson,
Owen,
Chung,
Smart,
Supplisson,
Thomas,
Graham,
Armstrong,
Shiang,
Pearce,
Abbott,
Beatty,
Tijssen,
Harvey,
Harvey,
Zuberi,
Duguid,
Boehning,
Snyder,
Bada,
Becker,
McDonald,
Glavin,
Korman,
Kojima,
Gomori,
Gutman,
Ergaz,
Sato,
Boneh,
Kure,
Ichinohe,
Richard,
Compton,
Bailey,
Epstein,
Hohl,
Smith,
Bale,
Itin,
DiGiovanna,
Lynch,
Kelleher,
Ogg,
Olson,
Dyer,
Goulder,
Conlon,
Holmes,
Long,
Sullivan,
Workman,
Allen,
McMichael,
Wilson,
Brander,
Jones,
Shaunak,
Rowland-Jones,
Phillips,
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- Nonketotic hyperglycinemia. Glycine accumulation due to absence of glycerine cleavage in brain. Perry, T.L., Urquhart, N., MacLean, J., Evans, M.E., Hansen, S., Davidson, G.F., Applegarth, D.A., MacLeod, P.J., Lock, J.E. N. Engl. J. Med. (1975)
- Identification of "nodule-specific" host proteins (nodoulins) involved in the development of rhizobium-legume symbiosis. Legocki, R.P., Verma, D.P. Cell (1980)
- Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion. Kingsmore, S.F., Giros, B., Suh, D., Bieniarz, M., Caron, M.G., Seldin, M.F. Nat. Genet. (1994)
- Assembly and release of HIV-1 precursor Pr55gag virus-like particles from recombinant baculovirus-infected insect cells. Gheysen, D., Jacobs, E., de Foresta, F., Thiriart, C., Francotte, M., Thines, D., De Wilde, M. Cell (1989)
- Glycine 699 is pivotal for the motor activity of skeletal muscle myosin. Kinose, F., Wang, S.X., Kidambi, U.S., Moncman, C.L., Winkelmann, D.A. J. Cell Biol. (1996)
- Persistent NKH with transient or absent symptoms and a homozygous GLDC mutation. Korman, S.H., Boneh, A., Ichinohe, A., Kojima, K., Sato, K., Ergaz, Z., Gomori, J.M., Gutman, A., Kure, S. Ann. Neurol. (2004)
- Presymptomatic hippocampal atrophy in Alzheimer's disease. A longitudinal MRI study. Fox, N.C., Warrington, E.K., Freeborough, P.A., Hartikainen, P., Kennedy, A.M., Stevens, J.M., Rossor, M.N. Brain (1996)
- Oxidative fragmentation of collagen and prolyl peptide by Cu(II)/H2O2. Conversion of proline residue to 2-pyrrolidone. Kato, Y., Uchida, K., Kawakishi, S. J. Biol. Chem. (1992)
- Amino acids in bipolar affective disorders: increased glycine levels in erythrocytes. Rosenblatt, S., Gaull, G.E., Chanley, J.D., Rosenthal, J.S., Smith, H., Sarkozi, L. The American journal of psychiatry. (1979)
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- Molecular structure and function of the glycine receptor chloride channel. Lynch, J.W. Physiol. Rev. (2004)
- Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease. Rees, M.I., Harvey, K., Pearce, B.R., Chung, S.K., Duguid, I.C., Thomas, P., Beatty, S., Graham, G.E., Armstrong, L., Shiang, R., Abbott, K.J., Zuberi, S.M., Stephenson, J.B., Owen, M.J., Tijssen, M.A., van den Maagdenberg, A.M., Smart, T.G., Supplisson, S., Harvey, R.J. Nat. Genet. (2006)
- Keratin 8 mutations in patients with cryptogenic liver disease. Ku, N.O., Gish, R., Wright, T.L., Omary, M.B. N. Engl. J. Med. (2001)
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- Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia. Rousseau, F., Bonaventure, J., Legeai-Mallet, L., Pelet, A., Rozet, J.M., Maroteaux, P., Le Merrer, M., Munnich, A. Nature (1994)
- Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses. Kelleher, A.D., Long, C., Holmes, E.C., Allen, R.L., Wilson, J., Conlon, C., Workman, C., Shaunak, S., Olson, K., Goulder, P., Brander, C., Ogg, G., Sullivan, J.S., Dyer, W., Jones, I., McMichael, A.J., Rowland-Jones, S., Phillips, R.E. J. Exp. Med. (2001)
- Epstein-Barr virus-induced autoimmune responses. II. Immunoglobulin G autoantibodies to mimicking and nonmimicking epitopes. Presence in autoimmune disease. Vaughan, J.H., Nguyen, M.D., Valbracht, J.R., Patrick, K., Rhodes, G.H. J. Clin. Invest. (1995)
- Distinct and overlapping functions of allelic forms of human mannose binding protein. Super, M., Gillies, S.D., Foley, S., Sastry, K., Schweinle, J.E., Silverman, V.J., Ezekowitz, R.A. Nat. Genet. (1992)
- Pseudomonas syringae pv. syringae harpinPss: a protein that is secreted via the Hrp pathway and elicits the hypersensitive response in plants. He, S.Y., Huang, H.C., Collmer, A. Cell (1993)
- Mutations in the alpha 1 subunit of the inhibitory glycine receptor cause the dominant neurologic disorder, hyperekplexia. Shiang, R., Ryan, S.G., Zhu, Y.Z., Hahn, A.F., O'Connell, P., Wasmuth, J.J. Nat. Genet. (1993)
- Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis. Bulman, M.P., Kusumi, K., Frayling, T.M., McKeown, C., Garrett, C., Lander, E.S., Krumlauf, R., Hattersley, A.T., Ellard, S., Turnpenny, P.D. Nat. Genet. (2000)
- Secretion of a lambda 2 immunoglobulin chain is prevented by a single amino acid substitution in its variable region. Wu, G.E., Hozumi, N., Murialdo, H. Cell (1983)
- Rous sarcoma virus transforming protein lacking myristic acid phosphorylates known polypeptide substrates without inducing transformation. Kamps, M.P., Buss, J.E., Sefton, B.M. Cell (1986)
- Modulation of glycine receptor chloride channels by cAMP-dependent protein kinase in spinal trigeminal neurons. Song, Y.M., Huang, L.Y. Nature (1990)
- Novel neural modulators. Boehning, D., Snyder, S.H. Annu. Rev. Neurosci. (2003)
- Pancreastatin, a novel pancreatic peptide that inhibits insulin secretion. Tatemoto, K., Efendić, S., Mutt, V., Makk, G., Feistner, G.J., Barchas, J.D. Nature (1986)
- A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli. Higgins, C.F., Dorman, C.J., Stirling, D.A., Waddell, L., Booth, I.R., May, G., Bremer, E. Cell (1988)
- Mutations in the human connexin gene GJB3 cause erythrokeratodermia variabilis. Richard, G., Smith, L.E., Bailey, R.A., Itin, P., Hohl, D., Epstein, E.H., DiGiovanna, J.J., Compton, J.G., Bale, S.J. Nat. Genet. (1998)
- Activation of multiple-conductance state chloride channels in spinal neurones by glycine and GABA. Hamill, O.P., Bormann, J., Sakmann, B. Nature (1983)
- Hippocampus-dependent learning facilitated by a monoclonal antibody or D-cycloserine. Thompson, L.T., Moskal, J.R., Disterhoft, J.F. Nature (1992)
- Molecular basis for substrate discrimination by glycine transporters. Vandenberg, R.J., Shaddick, K., Ju, P. J. Biol. Chem. (2007)
- Relationship between self-association of glycine molecules in supersaturated solutions and solid state outcome. Erdemir, D., Chattopadhyay, S., Guo, L., Ilavsky, J., Amenitsch, H., Segre, C.U., Myerson, A.S. Phys. Rev. Lett. (2007)
- Conformational variability of the glycine receptor M2 domain in response to activation by different agonists. Pless, S.A., Dibas, M.I., Lester, H.A., Lynch, J.W. J. Biol. Chem. (2007)
- Roles for loop 2 residues of alpha1 glycine receptors in agonist activation. Crawford, D.K., Perkins, D.I., Trudell, J.R., Bertaccini, E.J., Davies, D.L., Alkana, R.L. J. Biol. Chem. (2008)
- The role of the mitochondrial glycine cleavage complex in the metabolism and virulence of the protozoan parasite Leishmania major. Scott, D.A., Hickerson, S.M., Vickers, T.J., Beverley, S.M. J. Biol. Chem. (2008)
- Ligand-specific conformational changes in the alpha1 glycine receptor ligand-binding domain. Pless, S.A., Lynch, J.W. J. Biol. Chem. (2009)
- Serine and glycine metabolism in cancer. Amelio, I., Cutruzzolá, F., Antonov, A., Agostini, M., Melino, G. Trends Biochem. Sci. (2014)
- A missense mutation in the gene encoding the alpha 1 subunit of the inhibitory glycine receptor in the spasmodic mouse. Ryan, S.G., Buckwalter, M.S., Lynch, J.W., Handford, C.A., Segura, L., Shiang, R., Wasmuth, J.J., Camper, S.A., Schofield, P., O'Connell, P. Nat. Genet. (1994)
- Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine. Okawa, A., Nakamura, I., Goto, S., Moriya, H., Nakamura, Y., Ikegawa, S. Nat. Genet. (1998)
- Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits. Chatterton, J.E., Awobuluyi, M., Premkumar, L.S., Takahashi, H., Talantova, M., Shin, Y., Cui, J., Tu, S., Sevarino, K.A., Nakanishi, N., Tong, G., Lipton, S.A., Zhang, D. Nature (2002)
- The integrity of the glycine co-agonist binding site of N-methyl-D-aspartate receptors is a functional quality control checkpoint for cell surface delivery. Kenny, A.V., Cousins, S.L., Pinho, L., Stephenson, F.A. J. Biol. Chem. (2009)
- Gephyrin antisense oligonucleotides prevent glycine receptor clustering in spinal neurons. Kirsch, J., Wolters, I., Triller, A., Betz, H. Nature (1993)
- Precise inhibition is essential for microsecond interaural time difference coding. Brand, A., Behrend, O., Marquardt, T., McAlpine, D., Grothe, B. Nature (2002)
- Triggering of allostery in an enzyme by a point mutation: ornithine transcarbamoylase. Kuo, L.C., Zambidis, I., Caron, C. Science (1989)
- A search for endogenous amino acids in martian meteorite ALH84001. Bada, J.L., Glavin, D.P., McDonald, G.D., Becker, L. Science (1998)
- Purification and sequence analysis of bioactive atrial peptides (atriopeptins). Currie, M.G., Geller, D.M., Cole, B.R., Siegel, N.R., Fok, K.F., Adams, S.P., Eubanks, S.R., Galluppi, G.R., Needleman, P. Science (1984)