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Chemical Compound Review

inositol     cyclohexane-1,2,3,4,5,6-hexol

Synonyms: Inosital, Scyllite, Cocositol, Dambose, Inosite, ...
 
 
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Disease relevance of inositol

 

Psychiatry related information on inositol

 

High impact information on inositol

 

Chemical compound and disease context of inositol

 

Biological context of inositol

 

Anatomical context of inositol

 

Associations of inositol with other chemical compounds

 

Gene context of inositol

 

Analytical, diagnostic and therapeutic context of inositol

References

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  20. Role of sorbitol accumulation and myo-inositol depletion in paranodal swelling of large myelinated nerve fibers in the insulin-deficient spontaneously diabetic bio-breeding rat. Reversal by insulin replacement, an aldose reductase inhibitor, and myo-inositol. Greene, D.A., Chakrabarti, S., Lattimer, S.A., Sima, A.A. J. Clin. Invest. (1987) [Pubmed]
  21. PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254. Kim, H.K., Kim, J.W., Zilberstein, A., Margolis, B., Kim, J.G., Schlessinger, J., Rhee, S.G. Cell (1991) [Pubmed]
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  23. Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions. Luo, H.R., Huang, Y.E., Chen, J.C., Saiardi, A., Iijima, M., Ye, K., Huang, Y., Nagata, E., Devreotes, P., Snyder, S.H. Cell (2003) [Pubmed]
  24. Growth signal transduction: rapid activation of covalently bound ornithine decarboxylase during phosphatidylinositol breakdown. Mustelin, T., Pösö, H., Lapinjoki, S.P., Gynther, J., Andersson, L.C. Cell (1987) [Pubmed]
  25. Effects of bombesin and insulin on inositol (1,4,5)trisphosphate and inositol (1,3,4)trisphosphate formation in Swiss 3T3 cells. Heslop, J.P., Blakeley, D.M., Brown, K.D., Irvine, R.F., Berridge, M.J. Cell (1986) [Pubmed]
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  27. Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production. Wakelam, M.J., Davies, S.A., Houslay, M.D., McKay, I., Marshall, C.J., Hall, A. Nature (1986) [Pubmed]
  28. Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling. Ono, M., Okada, H., Bolland, S., Yanagi, S., Kurosaki, T., Ravetch, J.V. Cell (1997) [Pubmed]
  29. Inositol trisphosphate receptor localization in brain: variable stoichiometry with protein kinase C. Worley, P.F., Baraban, J.M., Colvin, J.S., Snyder, S.H. Nature (1987) [Pubmed]
  30. Stepwise phosphorylation of myo-inositol leading to myo-inositol hexakisphosphate in Dictyostelium. Stephens, L.R., Irvine, R.F. Nature (1990) [Pubmed]
  31. Bidirectional control of cytosolic free calcium by thyrotropin-releasing hormone in pituitary cells. Drummond, A.H. Nature (1985) [Pubmed]
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  33. The role of inositol acylation and inositol deacylation in the Toxoplasma gondii glycosylphosphatidylinositol biosynthetic pathway. Smith, T.K., Kimmel, J., Azzouz, N., Shams-Eldin, H., Schwarz, R.T. J. Biol. Chem. (2007) [Pubmed]
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  35. Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cox, J.S., Shamu, C.E., Walter, P. Cell (1993) [Pubmed]
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  37. The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase. Attree, O., Olivos, I.M., Okabe, I., Bailey, L.C., Nelson, D.L., Lewis, R.A., McInnes, R.R., Nussbaum, R.L. Nature (1992) [Pubmed]
  38. Altered aldose reductase gene regulation in cultured human retinal pigment epithelial cells. Henry, D.N., Del Monte, M., Greene, D.A., Killen, P.D. J. Clin. Invest. (1993) [Pubmed]
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  41. G-protein signaling through tubby proteins. Santagata, S., Boggon, T.J., Baird, C.L., Gomez, C.A., Zhao, J., Shan, W.S., Myszka, D.G., Shapiro, L. Science (2001) [Pubmed]
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