Chemical Compound Review:
malonate propanedioate
Synonyms:
malonoate, malonyl, malo, Propanedioate, MALONATE ION, ...
This record was replaced with 867.
- Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia. Schulz, J.B., Weller, M., Matthews, R.T., Heneka, M.T., Groscurth, P., Martinou, J.C., Lommatzsch, J., von Coelln, R., Wüllner, U., Löschmann, P.A., Beal, M.F., Dichgans, J., Klockgether, T. Cell Death Differ. (1998)
- Malonyl coenzyme A synthetase. Purification and properties. Kim, Y.S., Bang, S.K. J. Biol. Chem. (1985)
- Identification of the yeast mitochondrial transporter for oxaloacetate and sulfate. Palmieri, L., Vozza, A., Agrimi, G., De Marco, V., Runswick, M.J., Palmieri, F., Walker, J.E. J. Biol. Chem. (1999)
- Purification and properties of a novel type of malonate decarboxylase from Acinetobacter calcoaceticus. Kim, Y.S., Byun, H.S. J. Biol. Chem. (1994)
- Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription. Calkins, M.J., Jakel, R.J., Johnson, D.A., Chan, K., Kan, Y.W., Johnson, J.A. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Disparate mechanisms for hypoxic cell injury in different nephron segments. Studies in the isolated perfused rat kidney. Brezis, M., Shanley, P., Silva, P., Spokes, K., Lear, S., Epstein, F.H., Rosen, S. J. Clin. Invest. (1985)
- OH-Pd(0) interaction as a stabilizing factor in palladium-catalyzed allylic alkylations. Hallman, K., Frölander, A., Wondimagegn, T., Svensson, M., Moberg, C. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Possible occurrence and role of an essential histidyl residue in succinate dehydrogenase. Vik, S.B., Hatefi, Y. Proc. Natl. Acad. Sci. U.S.A. (1981)
- Improved therapeutic window for treatment of histotoxic hypoxia with a free radical spin trap. Schulz, J.B., Matthews, R.T., Jenkins, B.G., Brar, P., Beal, M.F. J. Cereb. Blood Flow Metab. (1995)
- Involvement of free radicals in excitotoxicity in vivo. Schulz, J.B., Henshaw, D.R., Siwek, D., Jenkins, B.G., Ferrante, R.J., Cipolloni, P.B., Kowall, N.W., Rosen, B.R., Beal, M.F. J. Neurochem. (1995)
- Toxicity of dopamine to striatal neurons in vitro and potentiation of cell death by a mitochondrial inhibitor. McLaughlin, B.A., Nelson, D., Erecińska, M., Chesselet, M.F. J. Neurochem. (1998)
- Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate. Greene, J.G., Greenamyre, J.T. J. Neurochem. (1995)
- Identification of the active site of phosphoribosyl-dephospho-coenzyme A transferase and relationship of the enzyme to an ancient class of nucleotidyltransferases. Hoenke, S., Schmid, M., Dimroth, P. Biochemistry (2000)
- Mitochondrial defect in Huntington's disease caudate nucleus. Gu, M., Gash, M.T., Mann, V.M., Javoy-Agid, F., Cooper, J.M., Schapira, A.H. Ann. Neurol. (1996)
- Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate. Beal, M.F., Henshaw, D.R., Jenkins, B.G., Rosen, B.R., Schulz, J.B. Ann. Neurol. (1994)
- Proton re-uptake partitioning between uncoupling protein and ATP synthase during benzohydroxamic acid-resistant state 3 respiration in tomato fruit mitochondria. Jarmuszkiewicz, W., Almeida, A.M., Vercesi, A.E., Sluse, F.E., Sluse-Goffart, C.M. J. Biol. Chem. (2000)
- Neurodegeneration in methylmalonic aciduria involves inhibition of complex II and the tricarboxylic acid cycle, and synergistically acting excitotoxicity. Okun, J.G., Hörster, F., Farkas, L.M., Feyh, P., Hinz, A., Sauer, S., Hoffmann, G.F., Unsicker, K., Mayatepek, E., Kölker, S. J. Biol. Chem. (2002)
- Re: Effects of bidentate malonate ligand on the utilization and cytotoxicity of platinum compounds in the L1210 cell line. Wyrick, S.D., Chaney, S.G. Cancer Res. (1987)
- Ammonia formation in isolated rat liver mitochondria. LaNoue, K.F., Schoolwerth, A.C., Pease, A.J. J. Biol. Chem. (1983)
- Quantitation of the efflux of acylcarnitines from rat heart, brain, and liver mitochondria. Lysiak, W., Toth, P.P., Suelter, C.H., Bieber, L.L. J. Biol. Chem. (1986)
- Indirect inactivation of rabbit reticulocyte initiation factor eIF-2 by helenalin and bis(helenalinyl) malonate. Williams, W.L., Chaney, S.G., Hall, I.H., Lee, K.H. Biochemistry (1984)
- Localization of the substrate and oxalacetate binding site of succinate dehydrogenase. Kenney, W.C., Mowery, P.C., Seng, R.L., Singer, T.P. J. Biol. Chem. (1976)
- Adenosine triphosphate synthesis by electrochemical proton gradient in vesicles reconstituted from purified adenosine triphosphatase and phospholipids of thermophilic bacterium. Sone, N., Yoshida, M., Hirata, H., Kagawa, Y. J. Biol. Chem. (1977)
- Roles of the active site water, histidine 303, and phenylalanine 396 in the catalytic mechanism of the elongation condensing enzyme of Streptococcus pneumoniae. Zhang, Y.M., Hurlbert, J., White, S.W., Rock, C.O. J. Biol. Chem. (2006)
- Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant. Andreassen, O.A., Ferrante, R.J., Hughes, D.B., Klivenyi, P., Dedeoglu, A., Ona, V.O., Friedlander, R.M., Beal, M.F. J. Neurochem. (2000)
- Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length. Hansson, O., Castilho, R.F., Korhonen, L., Lindholm, D., Bates, G.P., Brundin, P. J. Neurochem. (2001)
- Malonyl-coenzyme A:acyl carrier protein acyltransferase of Streptomyces glaucescens: a possible link between fatty acid and polyketide biosynthesis. Summers, R.G., Ali, A., Shen, B., Wessel, W.A., Hutchinson, C.R. Biochemistry (1995)
- Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates. Innocenti, A., Vullo, D., Scozzafava, A., Casey, J.R., Supuran, C. Bioorg. Med. Chem. Lett. (2005)
- Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity. Klivenyi, P., Starkov, A.A., Calingasan, N.Y., Gardian, G., Browne, S.E., Yang, L., Bubber, P., Gibson, G.E., Patel, M.S., Beal, M.F. J. Neurochem. (2004)
- Nonezymatic formation of succinate in mitochondria under oxidative stress. Fedotcheva, N.I., Sokolov, A.P., Kondrashova, M.N. Free Radic. Biol. Med. (2006)
- Variable proton conductance of submitochondrial particles. Sorgato, M.C., Ferguson, S.J. Biochemistry (1979)
- Ligand-assisted inhibition in cytochrome P450 158A2 from Streptomyces coelicolor A3(2). Zhao, B., Waterman, M.R., Isin, E.M., Sundaramoorthy, M., Podust, L.M. Biochemistry (2006)
- Minocycline fails to protect cerebellar granular cell cultures against malonate-induced cell death. Fernandez-Gomez, F.J., Gomez-Lazaro, M., Pastor, D., Calvo, S., Aguirre, N., Galindo, M.F., Jordán, J. Neurobiol. Dis. (2005)
- Role for dopamine in malonate-induced damage in vivo in striatum and in vitro in mesencephalic cultures. Moy, L.Y., Zeevalk, G.D., Sonsalla, P.K. J. Neurochem. (2000)