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LHFP  -  lipoma HMGIC fusion partner

Homo sapiens

Synonyms: Lipoma HMGIC fusion partner, MGC22429
 
 
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Disease relevance of LHFP

 

High impact information on LHFP

  • LHFP, a novel translocation partner gene of HMGIC in a lipoma, is a member of a new family of LHFP-like genes [1].
  • Nucleotide sequence analysis of the composite LHFP cDNA revealed an open reading frame encoding a protein of 200 amino acids [1].
  • The results of the present study demonstrated the absence of the HMGIC-LHFP fusion in three pulmonary chondroid hamartomas (PCH) with complex aberrations involving chromosomal regions 12q13 through q15 and 13q12q through q14 and one PCH with a simple t(12;13)(q14 through 15;q13) by reverse transcription-polymerase chain reaction [2].
 

Biological context of LHFP

References

  1. LHFP, a novel translocation partner gene of HMGIC in a lipoma, is a member of a new family of LHFP-like genes. Petit, M.M., Schoenmakers, E.F., Huysmans, C., Geurts, J.M., Mandahl, N., Van de Ven, W.J. Genomics (1999) [Pubmed]
  2. Absence of HMGIC-LHFP fusion in pulmonary chondroid hamartomas with aberrations involving chromosomal regions 12q13 through 15 and 13q12 through q14. Rogalla, P., Lemke, I., Bullerdiek, J. Cancer Genet. Cytogenet. (2002) [Pubmed]
 
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