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SLC25A17  -  solute carrier family 25 (mitochondrial...

Homo sapiens

Synonyms: 34 kDa peroxisomal membrane protein, PMP34, Peroxisomal membrane protein PMP34, Solute carrier family 25 member 17
 
 
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High impact information on SLC25A17

  • In addition, we demonstrate that PEX19, a factor required for peroxisomal membrane biogenesis, interacts with the two minimal targeting regions of PMP34 [1].
  • Here, we show that the metabolite transporter PMP34, an integral PMP, contains at least two nonoverlapping sets of targeting information, either of which is sufficient for insertion into the peroxisome membrane [1].
  • Three hydrophobic transmembrane segments linked in a flanking region of the basic loop were essential for integration of PMP34 to peroxisome membranes [2].
  • Transmembrane topology of PMP34 was determined by differential permeabilization and immunofluorescent staining of HeLa cells ectopically expressing PMP34 as well as of Chinese hamster ovary-K1 expressing epitope-tagged PMP34 [2].
  • As opposed to PMP47, PMP34 was found to expose its N- and C-terminal parts to the cytosol [2].
 

Biological context of SLC25A17

 

Associations of SLC25A17 with chemical compounds

  • In this paper we report the identification of PMP34, a peroxisomal membrane protein belonging to the mitochondrial solute carrier family, as an adenine nucleotide transporter [4].

References

 
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