Gene Review:
GNA13 - guanine nucleotide binding protein (G...
Homo sapiens
Synonyms:
G alpha-13, G-protein subunit alpha-13, G13, Guanine nucleotide-binding protein subunit alpha-13, MGC46138
Chou,
- The alpha-subunits of G-proteins G12 and G13 are palmitoylated, but not amidically myristoylated. Veit, M., Nürnberg, B., Spicher, K., Harteneck, C., Ponimaskin, E., Schultz, G., Schmidt, M.F. FEBS Lett. (1994)
- G protein-coupled receptors and signaling pathways regulating growth responses. Post, G.R., Brown, J.H. FASEB J. (1996)
- Cortical somatosensory evoked potentials. II. Effects of excision of somatosensory or motor cortex in humans and monkeys. Allison, T., Wood, C.C., McCarthy, G., Spencer, D.D. J. Neurophysiol. (1991)
- Serological and genomic characterization of equine rotavirus VP4 proteins identifies three different P serotypes. Isa, P., Snodgrass, D.R. Virology (1994)
- Concomitant regulation of Ca2+ mobilization and G13 expression in human erythroleukemia cells. Michel, M.C. Eur. J. Pharmacol. (1998)
- p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13. Kozasa, T., Jiang, X., Hart, M.J., Sternweis, P.M., Singer, W.D., Gilman, A.G., Bollag, G., Sternweis, P.C. Science (1998)
- RGS16 inhibits signalling through the G alpha 13-Rho axis. Johnson, E.N., Seasholtz, T.M., Waheed, A.A., Kreutz, B., Suzuki, N., Kozasa, T., Jones, T.L., Brown, J.H., Druey, K.M. Nat. Cell Biol. (2003)
- Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement. Kabarowski, J.H., Feramisco, J.D., Le, L.Q., Gu, J.L., Luoh, S.W., Simon, M.I., Witte, O.N. Proc. Natl. Acad. Sci. U.S.A. (2000)
- The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families. Laugwitz, K.L., Allgeier, A., Offermanns, S., Spicher, K., Van Sande, J., Dumont, J.E., Schultz, G. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Stimulation of cAMP accumulation by the cloned Xenopus melatonin receptor through Gi and Gz proteins. Yung, L.Y., Tsim, S.T., Wong, Y.H. FEBS Lett. (1995)
- Expression of GTP-binding protein alpha subunits in human thymocytes. Kabouridis, P.S., Waters, S.T., Escobar, S., Stanners, J., Tsoukas, C.D. Mol. Cell. Biochem. (1995)
- G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. Offermanns, S., Laugwitz, K.L., Spicher, K., Schultz, G. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Galpha12 and galpha13 are phosphorylated during platelet activation. Offermanns, S., Hu, Y.H., Simon, M.I. J. Biol. Chem. (1996)
- Coupling interaction between thromboxane A2 receptor and alpha-13 subunit of guanine nucleotide-binding protein. Chou, K.C. J. Proteome Res. (2005)
- Ca2+ signalling in K562 human erythroleukaemia cells: effect of dimethyl sulphoxide and role of G-proteins in thrombin- and thromboxane A2-activated pathways. Thomas, C.P., Dunn, M.J., Mattera, R. Biochem. J. (1995)
- Characterization of G alpha 13-dependent plasma membrane recruitment of p115RhoGEF. Bhattacharyya, R., Wedegaertner, P.B. Biochem. J. (2003)
- Signaling by the G12 class of G proteins. Dhanasekaran, N., Dermott, J.M. Cell. Signal. (1996)
- Characterization of the cloned HEL cell thromboxane A2 receptor: evidence that the affinity state can be altered by G alpha 13 and G alpha q. Allan, C.J., Higashiura, K., Martin, M., Morinelli, T.A., Kurtz, D.T., Geoffroy, O., Meier, G.P., Gettys, T.W., Halushka, P.V. J. Pharmacol. Exp. Ther. (1996)
- Identification of Galpha13 as one of the G-proteins that couple to human platelet thromboxane A2 receptors. Djellas, Y., Manganello, J.M., Antonakis, K., Le Breton, G.C. J. Biol. Chem. (1999)
- The G12 family of G proteins as a reporter of thromboxane A2 receptor activity. Zhang, L., DiLizio, C., Kim, D., Smyth, E.M., Manning, D.R. Mol. Pharmacol. (2006)
- Interaction of heterotrimeric G13 protein with an A-kinase-anchoring protein 110 (AKAP110) mediates cAMP-independent PKA activation. Niu, J., Vaiskunaite, R., Suzuki, N., Kozasa, T., Carr, D.W., Dulin, N., Voyno-Yasenetskaya, T.A. Curr. Biol. (2001)
- Distinct biochemical properties of the native members of the G12 G-protein subfamily. Characterization of G alpha 12 purified from rat brain. Harhammer, R., Nürnberg, B., Harteneck, C., Leopoldt, D., Exner, T., Schultz, G. Biochem. J. (1996)
- G alpha 13-mediated transformation and apoptosis are permissively dependent on basal ERK activity. Adarichev, V.A., Vaiskunaite, R., Niu, J., Balyasnikova, I.V., Voyno-Yasenetskaya, T.A. Am. J. Physiol., Cell Physiol. (2003)
- Functional consequences of G alpha 13 mutations that disrupt interaction with p115RhoGEF. Grabocka, E., Wedegaertner, P.B. Oncogene (2005)
- Regulation of apoptosis by alpha-subunits of G12 and G13 proteins via apoptosis signal-regulating kinase-1. Berestetskaya, Y.V., Faure, M.P., Ichijo, H., Voyno-Yasenetskaya, T.A. J. Biol. Chem. (1998)