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Gene Review

Chn1  -  chimerin 1

Mus musculus

Synonyms: 0610007I19Rik, 0710001E19Rik, 1700112L09Rik, 2900046J01Rik, A-chimaerin, ...
 
 
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Disease relevance of Chn1

 

High impact information on Chn1

  • Real-time PCR analysis confirmed increases in the RNA expression of apoD (1.6-2.2-fold) and OSBPL8 (1.7-2.6-fold), and decreases in the RNA expression of n-chimerin (1.5-2.2-fold) and LPA acyltransferase (1.5-fold) in response to haloperidol and/or clozapine treatment [2].
  • Splenocytes were in vitro-stimulated with N. caninum (NC)- and T. gondii-antigens for assessing T cell proliferation and cytokine production [3].
  • Thus, the early stages of CV infection, including dephosphorylation of NC protein within endosomes, provide a possible site for controlling the initial stages of viral infection [4].
  • Free R1 protein appears to prevent the dephosphorylation of purified JHMV-NC substrate thereby possibly blocking the normal sequence of events necessary for NC release of viral genomes [4].
 

Biological context of Chn1

  • Viability indices of NC pups during days 0 to 7 of lactation were approximately 95% or more when they were fostered by either NC or eob mothers [1].

References

 
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