Gene Review:
OS9 - osteosarcoma amplified 9, endoplasmic...
Homo sapiens
Synonyms:
Amplified in osteosarcoma 9, ERLEC2, OS-9, Protein OS-9
- Cloning and characterization of three isoforms of OS-9 cDNA and expression of the OS-9 gene in various human tumor cell lines. Kimura, Y., Nakazawa, M., Yamada, M. J. Biochem. (1998)
- Complete sequence analysis of a gene (OS-9) ubiquitously expressed in human tissues and amplified in sarcomas. Su, Y.A., Hutter, C.M., Trent, J.M., Meltzer, P.S. Mol. Carcinog. (1996)
- A selective interaction between OS-9 and the carboxyl-terminal tail of meprin beta. Litovchick, L., Friedmann, E., Shaltiel, S. J. Biol. Chem. (2002)
- OS9 interacts with DC-STAMP and modulates its intracellular localization in response to TLR ligation. Jansen, B.J., Eleveld-Trancikova, D., Sanecka, A., van Hout-Kuijer, M., Hendriks, I.A., Looman, M.G., Leusen, J.H., Adema, G.J. Mol. Immunol. (2009)
- DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation. Eleveld-Trancikova, D., Sanecka, A., van Hout-Kuijer, M.A., Looman, M.W., Hendriks, I.A., Jansen, B.J., Adema, G.J. Mol. Immunol. (2010)
- Endoplasmic reticulum (ER) mannosidase I is compartmentalized and required for N-glycan trimming to Man5-6GlcNAc2 in glycoprotein ER-associated degradation. Avezov, E., Frenkel, Z., Ehrlich, M., Herscovics, A., Lederkremer, G.Z. Mol. Biol. Cell. (2008)
- YOS9, the putative yeast homolog of a gene amplified in osteosarcomas, is involved in the endoplasmic reticulum (ER)-Golgi transport of GPI-anchored proteins. Friedmann, E., Salzberg, Y., Weinberger, A., Shaltiel, S., Gerst, J.E. J. Biol. Chem. (2002)
- Identification of a new peptide recognized by autologous cytolytic T lymphocytes on a human melanoma. Vigneron, N., Ooms, A., Morel, S., Degiovanni, G., Van Den Eynde, B.J. Cancer Immun. (2002)
- OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha. Baek, J.H., Mahon, P.C., Oh, J., Kelly, B., Krishnamachary, B., Pearson, M., Chan, D.A., Giaccia, A.J., Semenza, G.L. Mol. Cell (2005)
- Ca2(+)-dependent interaction of N-copine, a member of the two C2 domain protein family, with OS-9, the product of a gene frequently amplified in osteosarcoma. Nakayama, T., Yaoi, T., Kuwajima, G., Yoshie, O., Sakata, T. FEBS Lett. (1999)
- A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal. Bernasconi, R., Pertel, T., Luban, J., Molinari, M. J. Biol. Chem. (2008)