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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
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SLC2A6  -  solute carrier family 2 (facilitated...

Homo sapiens

 
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High impact information on SLC2A6

  • GLUT6 was principally detected in testis germinal cells and GLUT9 was localized in kidney, liver, heart, and adrenal [1].
  • Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes [2].
  • Transfection of COS-7 cells with GLUT9 produced expression of a 46-kDa membrane protein which exhibited reconstitutable glucose-transport activity and low-affinity cytochalasin-B binding [2].
  • Expression of GLUT1, GLUT3 and GLUT9 proteins in normal human articular cartilage was confirmed by immunohistochemistry [3].
  • The mouse Glut8 gene spans approximately 9 kb, consists of 10 exons, and is highly similar to the human GLUT6 gene [4].

References

  1. Differential subcellular distribution of glucose transporters GLUT1-6 and GLUT9 in human cancer: Ultrastructural localization of GLUT1 and GLUT5 in breast tumor tissues. Godoy, A., Ulloa, V., Rodríguez, F., Reinicke, K., Yañez, A.J., García, M.d.e. .L., Medina, R.A., Carrasco, M., Barberis, S., Castro, T., Martínez, F., Koch, X., Vera, J.C., Poblete, M.T., Figueroa, C.D., Peruzzo, B., Pérez, F., Nualart, F. J. Cell. Physiol. (2006)
  2. Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes. Doege, H., Bocianski, A., Joost, H.G., Schürmann, A. Biochem. J. (2000)
  3. Molecular characterization and partial cDNA cloning of facilitative glucose transporters expressed in human articular chondrocytes; stimulation of 2-deoxyglucose uptake by IGF-I and elevated MMP-2 secretion by glucose deprivation. Richardson, S., Neama, G., Phillips, T., Bell, S., Carter, S.D., Moley, K.H., Moley, J.F., Vannucci, S.J., Mobasheri, A. Osteoarthr. Cartil. (2003)
  4. Mouse GLUT8: genomic organization and regulation of expression in 3T3-L1 adipocytes by glucose. Scheepers, A., Doege, H., Joost, H.G., Schürmann, A. Biochem. Biophys. Res. Commun. (2001)
 
 
 
 
 
 
 
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