Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

etv6 - ets variant gene 6 (TEL oncogene)

Danio rerio

Synonyms: id:ibd2308, tel

Onnebo, S.M. et al., Rottbauer, W. et al.

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Disease relevance of etv6

MATERIALS AND METHODS: To assess whether zebrafish could be utilized as a suitable model for the study of myeloid oncogenesis, we generated a zebrafish tel-jak2a fusion oncoprotein based on that seen in a case of chronic myeloid leukemia [1].

High impact information on etv6

Hematopoietic perturbation in zebrafish expressing a tel-jak2a fusion [1].
Surprisingly, ultrastructural analysis of tel cardiomyocytes reveals complete absence of organized thick myofilaments [2].

References

Hematopoietic perturbation in zebrafish expressing a tel-jak2a fusion. Onnebo, S.M., Condron, M.M., McPhee, D.O., Lieschke, G.J., Ward, A.C. Exp. Hematol. (2005) [Pubmed]
Cardiac myosin light chain-2: a novel essential component of thick-myofilament assembly and contractility of the heart. Rottbauer, W., Wessels, G., Dahme, T., Just, S., Trano, N., Hassel, D., Burns, C.G., Katus, H.A., Fishman, M.C. Circ. Res. (2006) [Pubmed]

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