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Gene Review

FAM129A  -  family with sequence similarity 129, member A

Homo sapiens

Synonyms: C1orf24, Cell growth-inhibiting gene 39 protein, GIG39, NIBAN, Protein FAM129A, ...
 
 
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Disease relevance of FAM129A

 

High impact information on FAM129A

  • CONCLUSIONS: We improved this diagnostic test by adding C1orf24 and ITM1 custom antibodies and showing use on a wider variety of thyroid pathology [2].
  • Reverse transcriptase-polymerase chain reaction and Western blot analysis of frozen tissue confirmed Niban expression at the molecular level in 4 cases of papillary carcinoma [1].
  • (3) Niban may be a molecular marker of the oxyphilic phenotype under various conditions [1].
  • Importantly, "Niban" is well expressed even in small primary rat Eker renal tumors, more than in progressed cell lines, and is also expressed in human renal carcinoma cells, but not in normal human or rat kidneys [3].
  • The majority of particles of commercial ant bait, including Amdro, Ascend, Award, Bushwhacker, Max Force with fipronil, and old and new formulations of Max Force with hydramethylnon, were 1,000 to 2,000 microm, but the majority of Niban particles were <420 microm [4].
 

Associations of FAM129A with chemical compounds

  • We evaluated the acceptance of three baits (Maxforce, Niban, and Baygon) to field colonies of the black carpenter ant in the spring and fall [5].
  • Maxforce bait granules were more readily accepted than either Niban or Baygon bait granules in the spring [5].
 

Analytical, diagnostic and therapeutic context of FAM129A

References

  1. A novel tumor marker, Niban, is expressed in subsets of thyroid tumors and Hashimoto's thyroiditis. Matsumoto, F., Fujii, H., Abe, M., Kajino, K., Kobayashi, T., Matsumoto, T., Ikeda, K., Hino, O. Hum. Pathol. (2006) [Pubmed]
  2. Diagnosis of suspicious thyroid nodules using four protein biomarkers. Cerutti, J.M., Latini, F.R., Nakabashi, C., Delcelo, R., Andrade, V.P., Amadei, M.J., Maciel, R.M., Hojaij, F.C., Hollis, D., Shoemaker, J., Riggins, G.J. Clin. Cancer Res. (2006) [Pubmed]
  3. A novel gene "Niban" upregulated in renal carcinogenesis: cloning by the cDNA-amplified fragment length polymorphism approach. Majima, S., Kajino, K., Fukuda, T., Otsuka, F., Hino, O. Jpn. J. Cancer Res. (2000) [Pubmed]
  4. Preference of food particle size among several urban ant species. Hooper-Bùi, L.M., Appel, A.G., Rust, M.K. J. Econ. Entomol. (2002) [Pubmed]
  5. Evaluation of control measures for black carpenter ant (Hymenoptera: Formicidae). Tripp, J.M., Suiter, D.R., Bennett, G.W., Klotz, J.H., Reid, B.L. J. Econ. Entomol. (2000) [Pubmed]
 
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