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Gene Review: 

Alan2  -  alloantigen response 2

Mus musculus

 
 
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High impact information on Alan2

  • A new type of genetic regulation of allogeneic response. A novel locus on mouse chromosome 4, Alan2 controls MLC reactivity to three different alloantigens: C57BL/10, BALB/c and CBA [1].
  • We analyzed the genetic basis of these strain differences using (OcB-9 x O20)F2 hybrids, and we mapped a novel locus Alan2 (Alloantigen response 2) on chromosome 4 near D4Mit72 that influences the response to all alloantigens tested [1].

References

  1. A new type of genetic regulation of allogeneic response. A novel locus on mouse chromosome 4, Alan2 controls MLC reactivity to three different alloantigens: C57BL/10, BALB/c and CBA. Havelková, H., Badalová, J., Demant, P., Lipoldová, M. Genes Immun. (2000) [Pubmed]
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