Gene Review:
CLCN3 - chloride channel, voltage-sensitive 3
Homo sapiens
Synonyms:
CLC3, Chloride channel protein 3, Chloride transporter ClC-3, ClC-3, H(+)/Cl(-) exchange transporter 3
- Expression of voltage-gated chloride channels in human glioma cells. Olsen, M.L., Schade, S., Lyons, S.A., Amaral, M.D., Sontheimer, H. J. Neurosci. (2003)
- ClC-3 expression enhances etoposide resistance by increasing acidification of the late endocytic compartment. Weylandt, K.H., Nebrig, M., Jansen-Rosseck, N., Amey, J.S., Carmena, D., Wiedenmann, B., Higgins, C.F., Sardini, A. Mol. Cancer Ther. (2007)
- The ClC-3 Cl- channel in cell volume regulation, proliferation and apoptosis in vascular smooth muscle cells. Guan, Y.Y., Wang, G.L., Zhou, J.G. Trends Pharmacol. Sci. (2006)
- Bcl-2-dependent modulation of swelling-activated Cl- current and ClC-3 expression in human prostate cancer epithelial cells. Lemonnier, L., Shuba, Y., Crepin, A., Roudbaraki, M., Slomianny, C., Mauroy, B., Nilius, B., Prevarskaya, N., Skryma, R. Cancer Res. (2004)
- ClC-3: more than just a volume-sensitive Cl- channel. Remillard, C.V., Yuan, J.X. Br. J. Pharmacol. (2005)
- CLC-3 Channels Modulate Excitatory Synaptic Transmission in Hippocampal Neurons. Wang, X.Q., Deriy, L.V., Foss, S., Huang, P., Lamb, F.S., Kaetzel, M.A., Bindokas, V., Marks, J.D., Nelson, D.J. Neuron (2006)
- Involvement of chloride channels in hepatic copper metabolism: ClC-4 promotes copper incorporation into ceruloplasmin. Wang, T., Weinman, S.A. Gastroenterology (2004)
- Differential expression of the human chloride channel genes in the trabecular meshwork under stress conditions. Comes, N., Gasull, X., Gual, A., Borrás, T. Exp. Eye Res. (2005)
- Characterization of the canine CLCN3 gene and evaluation as candidate for late-onset NCL. Wohlke, A., Distl, O., Drogemuller, C. BMC Genet. (2006)
- Expression of CLCN voltage-gated chloride channel genes in human blood vessels. Lamb, F.S., Clayton, G.H., Liu, B.X., Smith, R.L., Barna, T.J., Schutte, B.C. J. Mol. Cell. Cardiol. (1999)
- Chloride channels in physiological volume regulation of human spermatozoa. Yeung, C.H., Barfield, J.P., Cooper, T.G. Biol. Reprod. (2005)
- Involvement of ion channels in human eosinophil respiratory burst. Schwingshackl, A., Moqbel, R., Duszyk, M. J. Allergy Clin. Immunol. (2000)
- The human ClC-4 protein, a member of the CLC chloride channel/transporter family, is localized to the endoplasmic reticulum by its N-terminus. Okkenhaug, H., Weylandt, K.H., Carmena, D., Wells, D.J., Higgins, C.F., Sardini, A. FASEB J. (2006)
- ClC-3 is a fundamental molecular component of volume-sensitive outwardly rectifying Cl- channels and volume regulation in HeLa cells and Xenopus laevis oocytes. Hermoso, M., Satterwhite, C.M., Andrade, Y.N., Hidalgo, J., Wilson, S.M., Horowitz, B., Hume, J.R. J. Biol. Chem. (2002)
- Characterization of a human and murine gene (CLCN3) sharing similarities to voltage-gated chloride channels and to a yeast integral membrane protein. Borsani, G., Rugarli, E.I., Taglialatela, M., Wong, C., Ballabio, A. Genomics (1995)
- AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells. Salazar, G., Love, R., Styers, M.L., Werner, E., Peden, A., Rodriguez, S., Gearing, M., Wainer, B.H., Faundez, V. J. Biol. Chem. (2004)
- Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification. Barg, S., Huang, P., Eliasson, L., Nelson, D.J., Obermüller, S., Rorsman, P., Thévenod, F., Renström, E. J. Cell. Sci. (2001)
- Human ClC-3 is not the swelling-activated chloride channel involved in cell volume regulation. Weylandt, K.H., Valverde, M.A., Nobles, M., Raguz, S., Amey, J.S., Diaz, M., Nastrucci, C., Higgins, C.F., Sardini, A. J. Biol. Chem. (2001)
- Studies on the expression of mRNA for anion transport related proteins in corneal endothelial cells. Sun, X.C., McCutheon, C., Bertram, P., Xie, Q., Bonanno, J.A. Curr. Eye Res. (2001)
- Cell volume regulation and swelling-activated chloride channels. Sardini, A., Amey, J.S., Weylandt, K.H., Nobles, M., Valverde, M.A., Higgins, C.F. Biochim. Biophys. Acta (2003)
- Chloride channel expression in cultured human fetal RPE cells: response to oxidative stress. Wills, N.K., Weng, T., Mo, L., Hellmich, H.L., Yu, A., Wang, T., Buchheit, S., Godley, B.F. Invest. Ophthalmol. Vis. Sci. (2000)
- Intracellular localization of ClC chloride channels and their ability to form hetero-oligomers. Suzuki, T., Rai, T., Hayama, A., Sohara, E., Suda, S., Itoh, T., Sasaki, S., Uchida, S. J. Cell. Physiol. (2006)