Gene Review:
Bmx - BMX non-receptor tyrosine kinase
Mus musculus
Synonyms:
Bone marrow tyrosine kinase gene in chromosome X protein homolog, Cytoplasmic tyrosine-protein kinase BMX, Etk, Etk/Bmx, Tyro8
- Bmx tyrosine kinase transgene induces skin hyperplasia, inflammatory angiogenesis, and accelerated wound healing. Paavonen, K., Ekman, N., Wirzenius, M., Rajantie, I., Poutanen, M., Alitalo, K. Mol. Biol. Cell (2004)
- BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2. Tamagnone, L., Lahtinen, I., Mustonen, T., Virtaneva, K., Francis, F., Muscatelli, F., Alitalo, R., Smith, C.I., Larsson, C., Alitalo, K. Oncogene (1994)
- Etk/Bmx tyrosine kinase activates Pak1 and regulates tumorigenicity of breast cancer cells. Bagheri-Yarmand, R., Mandal, M., Taludker, A.H., Wang, R.A., Vadlamudi, R.K., Kung, H.J., Kumar, R. J. Biol. Chem. (2001)
- Tyrosine Kinase Etk/BMX Is Up-regulated in Human Prostate Cancer and Its Overexpression Induces Prostate Intraepithelial Neoplasia in Mouse. Dai, B., Kim, O., Xie, Y., Guo, Z., Xu, K., Wang, B., Kong, X., Melamed, J., Chen, H., Bieberich, C.J., Borowsky, A.D., Kung, H.J., Wei, G., Ostrowski, M.C., Brodie, A., Qiu, Y. Cancer Res. (2006)
- Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Galpha12/13. Mao, J., Xie, W., Yuan, H., Simon, M.I., Mano, H., Wu, D. EMBO J. (1998)
- Bmx tyrosine kinase is specifically expressed in the endocardium and the endothelium of large arteries. Ekman, N., Lymboussaki, A., Västrik, I., Sarvas, K., Kaipainen, A., Alitalo, K. Circulation (1997)
- Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium. Rajantie, I., Ekman, N., Iljin, K., Arighi, E., Gunji, Y., Kaukonen, J., Palotie, A., Dewerchin, M., Carmeliet, P., Alitalo, K. Mol. Cell. Biol. (2001)
- Predominant expression of murine Bmx tyrosine kinase in the granulo-monocytic lineage. Weil, D., Power, M.A., Smith, S.I., Li, C.L. Blood (1997)
- The Bmx tyrosine kinase is activated by IL-3 and G-CSF in a PI-3K dependent manner. Ekman, N., Arighi, E., Rajantie, I., Saharinen, P., Ristimäki, A., Silvennoinen, O., Alitalo, K. Oncogene (2000)
- Bovine herpesvirus tegument protein VP22 enhances thymidine kinase/ganciclovir suicide gene therapy for neuroblastomas compared to herpes simplex virus VP22. Qiu, Z., Harms, J.S., Zhu, J., Splitter, G.A. J. Virol. (2004)