Gene Review:
ADH4 - alcohol dehydrogenase 4 (class II), pi...
Homo sapiens
Synonyms:
ADH-2, Alcohol dehydrogenase 4, Alcohol dehydrogenase class II pi chain, HEL-S-4
- Immunochemical features in the classification of human alcohol dehydrogenase family. Lee, S.P., Chiang, C.P., Lee, S.L., Hsia, Y.J., Chuang, T.L., Lin, J.C., Liang, S.C., Nieh, S., Yin, S.J. Alcohol (2006)
- Function of cis-acting elements in human alcohol dehydrogenase 4 (ADH4) promoter and role of C/EBP proteins in gene expression. Li, M., Edenberg, H.J. DNA Cell Biol. (1998)
- ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies. Luo, X., Kranzler, H.R., Zuo, L., Yang, B.Z., Lappalainen, J., Gelernter, J. Pharmacogenet. Genomics (2005)
- Baboon alcohol dehydrogenase isozymes: phenotypic changes in liver following chronic consumption of alcohol. Holmes, R.S., VandeBerg, J.L. Isozymes Curr. Top. Biol. Med. Res. (1987)
- Personality traits of agreeableness and extraversion are associated with ADH4 variation. Luo, X., Kranzler, H.R., Zuo, L., Wang, S., Gelernter, J. Biol. Psychiatry (2007)
- Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis. Edenberg, H.J., Xuei, X., Chen, H.J., Tian, H., Wetherill, L.F., Dick, D.M., Almasy, L., Bierut, L., Bucholz, K.K., Goate, A., Hesselbrock, V., Kuperman, S., Nurnberger, J., Porjesz, B., Rice, J., Schuckit, M., Tischfield, J., Begleiter, H., Foroud, T. Hum. Mol. Genet. (2006)
- Biosynthesis of 9-cis-retinoic acid in vivo. The roles of different retinol dehydrogenases and a structure-activity analysis of microsomal retinol dehydrogenases. Tryggvason, K., Romert, A., Eriksson, U. J. Biol. Chem. (2001)
- ADH4 gene variation is associated with alcohol dependence and drug dependence in European Americans: results from HWD tests and case-control association studies. Luo, X., Kranzler, H.R., Zuo, L., Lappalainen, J., Yang, B.Z., Gelernter, J. Neuropsychopharmacology (2006)
- Cloning and characterization of the human ADH4 gene. von Bahr-Lindström, H., Jörnvall, H., Höög, J.O. Gene (1991)
- Thirteen single-nucleotide polymorphisms (SNPs) in the alcohol dehydrogenase 4 (ADH4) gene locus. Iida, A., Saito, S., Sekine, A., Kondo, K., Mishima, C., Kitamura, Y., Harigae, S., Osawa, S., Nakamura, Y. J. Hum. Genet. (2002)
- Molecular docking studies on interaction of diverse retinol structures with human alcohol dehydrogenases predict a broad role in retinoid ligand synthesis. Foglio, M.H., Duester, G. Biochim. Biophys. Acta (1999)
- The specificity of alcohol dehydrogenase with cis-retinoids. Activity with 11-cis-retinol and localization in retina. Martras, S., Alvarez, R., Martínez, S.E., Torres, D., Gallego, O., Duester, G., Farrés, J., de Lera, A.R., Parés, X. Eur. J. Biochem. (2004)
- Alcohol dehydrogenase genes: restriction fragment length polymorphisms for ADH4 (pi-ADH) and ADH5 (chi-ADH) and construction of haplotypes among different ADH classes. Edman, K., Maret, W. Hum. Genet. (1992)
- Functional assessment of human alcohol dehydrogenase family in ethanol metabolism: significance of first-pass metabolism. Lee, S.L., Chau, G.Y., Yao, C.T., Wu, C.W., Yin, S.J. Alcohol. Clin. Exp. Res. (2006)
- Mammalian alcohol dehydrogenase - functional and structural implications. Höög, J.O., Hedberg, J.J., Strömberg, P., Svensson, S. J. Biomed. Sci. (2001)
- Alcohol dehydrogenase alleles in Parkinson's disease. Buervenich, S., Sydow, O., Carmine, A., Zhang, Z., Anvret, M., Olson, L. Mov. Disord. (2000)
- Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid. Duester, G., Mic, F.A., Molotkov, A. Chem. Biol. Interact. (2003)