Gene Review:
Clu - clusterin
Mus musculus
Synonyms:
AI893575, Apo-J, ApoJ, Apoj, Apolipoprotein J, ...
- Clusterin contributes to caspase-3-independent brain injury following neonatal hypoxia-ischemia. Han, B.H., DeMattos, R.B., Dugan, L.L., Kim-Han, J.S., Brendza, R.P., Fryer, J.D., Kierson, M., Cirrito, J., Quick, K., Harmony, J.A., Aronow, B.J., Holtzman, D.M. Nat. Med. (2001)
- ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo. DeMattos, R.B., Cirrito, J.R., Parsadanian, M., May, P.C., O'Dell, M.A., Taylor, J.W., Harmony, J.A., Aronow, B.J., Bales, K.R., Paul, S.M., Holtzman, D.M. Neuron (2004)
- The SGP-2 gene is developmentally regulated in the mouse kidney and abnormally expressed in collecting duct cysts in polycystic kidney disease. Harding, M.A., Chadwick, L.J., Gattone, V.H., Calvet, J.P. Dev. Biol. (1991)
- Epidermal growth factor ameliorates autosomal recessive polycystic kidney disease in mice. Gattone, V.H., Lowden, D.A., Cowley, B.D. Dev. Biol. (1995)
- Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease. DeMattos, R.B., O'dell, M.A., Parsadanian, M., Taylor, J.W., Harmony, J.A., Bales, K.R., Paul, S.M., Aronow, B.J., Holtzman, D.M. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Immunocytochemical colocalization of clusterin in apoptotic photoreceptor cells in retinal degeneration slow rds mutant mouse retinas. Agarwal, N., Jomary, C., Jones, S.E., O'Rourke, K., Chaitin, M., Wordinger, R.J., Murphy, B.F. Biochem. Biophys. Res. Commun. (1996)
- Apolipoprotein J/clusterin limits the severity of murine autoimmune myocarditis. McLaughlin, L., Zhu, G., Mistry, M., Ley-Ebert, C., Stuart, W.D., Florio, C.J., Groen, P.A., Witt, S.A., Kimball, T.R., Witte, D.P., Harmony, J.A., Aronow, B.J. J. Clin. Invest. (2000)
- Heat shock-initiated apoptosis is accelerated and removal of damaged cells is delayed in the testis of clusterin/ApoJ knock-out mice. Bailey, R.W., Aronow, B., Harmony, J.A., Griswold, M.D. Biol. Reprod. (2002)
- Synergistic chemsensitization and inhibition of tumor growth and metastasis by the antisense oligodeoxynucleotide targeting clusterin gene in a human bladder cancer model. Miyake, H., Hara, I., Kamidono, S., Gleave, M.E. Clin. Cancer Res. (2001)
- Synergistic antitumor effect of combined use of adenoviral-mediated p53 gene transfer and antisense oligodeoxynucleotide targeting clusterin gene in an androgen-independent human prostate cancer model. Yamanaka, K., Gleave, M.E., Hara, I., Muramaki, M., Miyake, H. Mol. Cancer Ther. (2005)
- The chemopreventive action of catechins in the TRAMP mouse model of prostate carcinogenesis is accompanied by clusterin over-expression. Caporali, A., Davalli, P., Astancolle, S., D'Arca, D., Brausi, M., Bettuzzi, S., Corti, A. Carcinogenesis (2004)
- Assignment of the transcription factor GATA4 gene to human chromosome 8 and mouse chromosome 14: Gata4 is a candidate gene for Ds (disorganization). White, R.A., Dowler, L.L., Pasztor, L.M., Gatson, L.L., Adkison, L.R., Angeloni, S.V., Wilson, D.B. Genomics (1995)
- Low density lipoprotein receptor-related protein-2 expression in efferent duct and epididymal epithelia: evidence in rats for its in vivo role in endocytosis of apolipoprotein J/clusterin. Morales, C.R., Igdoura, S.A., Wosu, U.A., Boman, J., Argraves, W.S. Biol. Reprod. (1996)
- Mouse apolipoprotein J: characterization of a gene implicated in atherosclerosis. Jordan-Starck, T.C., Lund, S.D., Witte, D.P., Aronow, B.J., Ley, C.A., Stuart, W.D., Swertfeger, D.K., Clayton, L.R., Sells, S.F., Paigen, B. J. Lipid Res. (1994)
- Changes in levels of mRNAs of transforming growth factor (TGF)-beta1, -beta2, -beta3, TGF-beta type II receptor and sulfated glycoprotein-2 during apoptosis of mouse uterine epithelium. Wada, K., Nomura, S., Morii, E., Kitamura, Y., Nishizawa, Y., Miyake, A., Terada, N. J. Steroid Biochem. Mol. Biol. (1996)
- Photoreceptor cells in the vitiligo mouse die by apoptosis. TRPM-2/clusterin expression is increased in the neural retina and in the retinal pigment epithelium. Smith, S.B., Bora, N., McCool, D., Kutty, G., Wong, P., Kutty, R.K., Wiggert, B. Invest. Ophthalmol. Vis. Sci. (1995)
- Transglutaminase and clusterin induction during normal and abnormal limb development in the mouse. Adel Moallem, S., Hales, B.F. Biol. Reprod. (1996)
- Primary and secondary genetic responses after folic acid-induced acute renal injury in the mouse. Calvet, J.P., Chadwick, L.J. J. Am. Soc. Nephrol. (1994)
- Clusterin gene transcription is activated by caudal-related homeobox genes in intestinal epithelium. Suh, E., Wang, Z., Swain, G.P., Tenniswood, M., Traber, P.G. Am. J. Physiol. Gastrointest. Liver Physiol. (2001)
- EGF inhibits expression of WDNM1 and sulfated glycoprotein-2 genes in mammary epithelial cells. Lee, M., Hwang, I., Choi, Y., Paik, S., Lee, H.B., Baik, M. Biochem. Biophys. Res. Commun. (1997)
- Effects of clusterin overexpression on TNFalpha- and TGFbeta-mediated death of L929 cells. Humphreys, D., Hochgrebe, T.T., Easterbrook-Smith, S.B., Tenniswood, M.P., Wilson, M.R. Biochemistry (1997)
- Myc-transformed epithelial cells down-regulate clusterin, which inhibits their growth in vitro and carcinogenesis in vivo. Thomas-Tikhonenko, A., Viard-Leveugle, I., Dews, M., Wehrli, P., Sevignani, C., Yu, D., Ricci, S., el-Deiry, W., Aronow, B., Kaya, G., Saurat, J.H., French, L.E. Cancer Res. (2004)
- Targeted disruption of the murine lecithin:cholesterol acyltransferase gene is associated with reductions in plasma paraoxonase and platelet-activating factor acetylhydrolase activities but not in apolipoprotein J concentration. Forte, T.M., Oda, M.N., Knoff, L., Frei, B., Suh, J., Harmony, J.A., Stuart, W.D., Rubin, E.M., Ng, D.S. J. Lipid Res. (1999)
- Murine clusterin: molecular cloning and mRNA localization of a gene associated with epithelial differentiation processes during embryogenesis. French, L.E., Chonn, A., Ducrest, D., Baumann, B., Belin, D., Wohlwend, A., Kiss, J.Z., Sappino, A.P., Tschopp, J., Schifferli, J.A. J. Cell Biol. (1993)