Michael F. G. Murphy,
Costas N. Stefanis,
Marcus R. Munafò,
Hara Tsekou,
Nikolaos Smyrnis,
Tilmann Roehrs,
Marta Ramirez Gaite,
Klaus Berger,
Elaine C. Johnstone,
Jürgen Deckert,
Paul Aveyard,
Nicholas C. Stefanis,
Marek Drozdzik,
Anna Neumann,
Eng-King Tan,
Monika Bialecka,
Bernhard T. Baune,
Grzegorz Opala,
Christa Hohoff,
Boliang Guo,
Mateusz Kurzawski,
Dimitrios Avramopoulos,
Katharina Domschke,
Ioannis Evdokimidis,
Sünke Mortensen,
Gabriela Klodowska-Duda,
Volker Arolt,
- Breast cancer risk associated with genotype polymorphism of the estrogen-metabolizing genes CYP17, CYP1A1, and COMT: a multigenic study on cancer susceptibility. Huang, C.S., Chern, H.D., Chang, K.J., Cheng, C.W., Hsu, S.M., Shen, C.Y. Cancer Res. (1999)
- Polymorphisms of the estrogen-metabolizing genes CYP17 and catechol-O-methyltransferase and risk of epithelial ovarian cancer. Garner, E.I., Stokes, E.E., Berkowitz, R.S., Mok, S.C., Cramer, D.W. Cancer Res. (2002)
- Simultaneous inhibition of catechol-O-methyltransferase and monoamine oxidase A: effects on hemodynamics and catecholamine metabolism in healthy volunteers. Illi, A., Sundberg, S., Ojala-Karlsson, P., Scheinin, M., Gordin, A. Clin. Pharmacol. Ther. (1996)
- Characterization and implications of estrogenic down-regulation of human catechol-O-methyltransferase gene transcription. Xie, T., Ho, S.L., Ramsden, D. Mol. Pharmacol. (1999)
- Polymorphisms in estrogen bioactivation, detoxification and oxidative DNA base excision repair genes and prostate cancer risk. Nock, N.L., Cicek, M.S., Li, L., Liu, X., Rybicki, B.A., Moreira, A., Plummer, S.J., Casey, G., Witte, J.S. Carcinogenesis (2006)
- Catechol O-methyltransferase gene variant and birth weight predict early-onset antisocial behavior in children with attention-deficit/hyperactivity disorder. Thapar, A., Langley, K., Fowler, T., Rice, F., Turic, D., Whittinger, N., Aggleton, J., Van den Bree, M., Owen, M., O'Donovan, M. Arch. Gen. Psychiatry. (2005)
- COMT Val108/158Met gene variant, birth weight, and conduct disorder in children with ADHD. Sengupta, S.M., Grizenko, N., Schmitz, N., Schwartz, G., Ben Amor, L., Bellingham, J., de Guzman, R., Polotskaia, A., Ter Stepanian, M., Thakur, G., Joober, R. J. Am. Acad. Child. Adolesc. Psychiatry. (2006)
- Aggressive behavior in schizophrenia is associated with the low enzyme activity COMT polymorphism: a replication study. Strous, R.D., Nolan, K.A., Lapidus, R., Diaz, L., Saito, T., Lachman, H.M. Am. J. Med. Genet. B. Neuropsychiatr. Genet. (2003)
- Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder. Rotondo, A., Mazzanti, C., Dell'Osso, L., Rucci, P., Sullivan, P., Bouanani, S., Gonnelli, C., Goldman, D., Cassano, G.B. The American journal of psychiatry. (2002)
- MAO-A and COMT polymorphisms and gene effects in narcolepsy. Dauvilliers, Y., Neidhart, E., Lecendreux, M., Billiard, M., Tafti, M. Mol. Psychiatry (2001)
- Family-based association studies support a sexually dimorphic effect of COMT and MAOA on genetic susceptibility to obsessive-compulsive disorder. Karayiorgou, M., Sobin, C., Blundell, M.L., Galke, B.L., Malinova, L., Goldberg, P., Ott, J., Gogos, J.A. Biol. Psychiatry (1999)
- Effect of schizotypy on cognitive performance and its tuning by COMT val158 met genotype variations in a large population of young men. Smyrnis, N., Avramopoulos, D., Evdokimidis, I., Stefanis, C.N., Tsekou, H., Stefanis, N.C. Biol. Psychiatry (2007)
- Association of COMT Val108/158Met genotype with smoking cessation. Munafò, M.R., Johnstone, E.C., Guo, B., Murphy, M.F., Aveyard, P. Pharmacogenet. Genomics (2008)
- The effect of catechol-O-methyltransferase Met/Val functional polymorphism on smoking cessation: retrospective and prospective analyses in a cohort study. Omidvar, M., Stolk, L., Uitterlinden, A.G., Hofman, A., Van Duijn, C.M., Tiemeier, H. Pharmacogenet. Genomics (2009)
- Crystal structure of catechol O-methyltransferase. Vidgren, J., Svensson, L.A., Liljas, A. Nature (1994)
- Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors. Männistö, P.T., Kaakkola, S. Pharmacol. Rev. (1999)
- Catechol-O-methyltransferase polymorphism is not associated with ovarian cancer risk. Goodman, J.E., Lavigne, J.A., Hengstler, J.G., Tanner, B., Helzlsouer, K.J., Yager, J.D. Cancer Epidemiol. Biomarkers Prev. (2000)
- Simultaneous MAO-B and COMT inhibition in L-Dopa-treated patients with Parkinson's disease. Lyytinen, J., Kaakkola, S., Ahtila, S., Tuomainen, P., Teräväinen, H. Mov. Disord. (1997)
- Haplotype relative risk study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD): association of the high-enzyme activity Val allele with ADHD impulsive-hyperactive phenotype. Eisenberg, J., Mei-Tal, G., Steinberg, A., Tartakovsky, E., Zohar, A., Gritsenko, I., Nemanov, L., Ebstein, R.P. Am. J. Med. Genet. (1999)
- Catecholamine metabolic pathways and exercise training. Plasma and urine catecholamines, metabolic enzymes, and chromogranin-A. Rogers, P.J., Tyce, G.M., Weinshilboum, R.M., O'Connor, D.T., Bailey, K.R., Bove, A.A. Circulation (1991)
- RGS4 mRNA expression in postmortem human cortex is associated with COMT Val158Met genotype and COMT enzyme activity. Lipska, B.K., Mitkus, S., Caruso, M., Hyde, T.M., Chen, J., Vakkalanka, R., Straub, R.E., Weinberger, D.R., Kleinman, J.E. Hum. Mol. Genet. (2006)
- Haplotypic association spanning the 22q11.21 genes COMT and ARVCF with schizophrenia. Sanders, A.R., Rusu, I., Duan, J., Vander Molen, J.E., Hou, C., Schwab, S.G., Wildenauer, D.B., Martinez, M., Gejman, P.V. Mol. Psychiatry (2005)
- Sulfate and methyldopa metabolism: metabolite patterns and platelet phenol sulfotransferase activity. Campbell, N.R., Sundaram, R.S., Werness, P.G., Van Loon, J., Weinshilboum, R.M. Clin. Pharmacol. Ther. (1985)
- Catecholamines block the antimitogenic effect of estradiol on human coronary artery smooth muscle cells. Dubey, R.K., Jackson, E.K., Gillespie, D.G., Zacharia, L.C., Imthurn, B. J. Clin. Endocrinol. Metab. (2004)
- Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: influence on risk of schizophrenia. Nicodemus, K.K., Kolachana, B.S., Vakkalanka, R., Straub, R.E., Giegling, I., Egan, M.F., Rujescu, D., Weinberger, D.R. Hum. Genet. (2007)
- Human catechol-O-methyltransferase down-regulation by estradiol. Jiang, H., Xie, T., Ramsden, D.B., Ho, S.L. Neuropharmacology (2003)
- Monoamine metabolism in human brain. Robinson, D.S., Sourkes, T.L., Nies, A., Harris, L.S., Spector, S., Bartlett, D.L., Kaye, I.S. Arch. Gen. Psychiatry (1977)
- Further evidence for a modulation of Novelty Seeking by DRD4 exon III, 5-HTTLPR, and COMT val/met variants. Strobel, A., Lesch, K.P., Jatzke, S., Paetzold, F., Brocke, B. Mol. Psychiatry (2003)
- Fluorodopa positron emission tomography with an inhibitor of catechol-O-methyltransferase: effect of the plasma 3-O-methyldopa fraction on data analysis. Ishikawa, T., Dhawan, V., Chaly, T., Robeson, W., Belakhlef, A., Mandel, F., Dahl, R., Margouleff, C., Eidelberg, D. J. Cereb. Blood Flow Metab. (1996)
- Cytochromes 1A1/1B1- and catechol-O-methyltransferase-derived metabolites mediate estradiol-induced antimitogenesis in human cardiac fibroblast. Dubey, R.K., Jackson, E.K., Gillespie, D.G., Rosselli, M., Barchiesi, F., Krust, A., Keller, H., Zacharia, L.C., Imthurn, B. J. Clin. Endocrinol. Metab. (2005)
- Catechol-o-methyltransferase enzyme activity and protein expression in human prefrontal cortex across the postnatal lifespan. Tunbridge, E.M., Weickert, C.S., Kleinman, J.E., Herman, M.M., Chen, J., Kolachana, B.S., Harrison, P.J., Weinberger, D.R. Cereb. Cortex (2007)
- The met(158) allele of catechol-O-methyltransferase (COMT) is associated with obsessive-compulsive disorder in men: case-control study and meta-analysis. Pooley, E.C., Fineberg, N., Harrison, P.J. Mol. Psychiatry (2007)
- Association of the COMT val158met variant with antidepressant treatment response in major depression. Baune, B.T., Hohoff, C., Berger, K., Neumann, A., Mortensen, S., Roehrs, T., Deckert, J., Arolt, V., Domschke, K. Neuropsychopharmacology (2008)
- The association of functional catechol-O-methyltransferase haplotypes with risk of Parkinson's disease, levodopa treatment response, and complications. Bialecka, M., Kurzawski, M., Klodowska-Duda, G., Opala, G., Tan, E.K., Drozdzik, M. Pharmacogenet. Genomics (2008)
- DRD2 C957T polymorphism interacts with the COMT Val158Met polymorphism in human working memory ability. Xu, H., Kellendonk, C.B., Simpson, E.H., Keilp, J.G., Bruder, G.E., Polan, H.J., Kandel, E.R., Gilliam, T.C. Schizophr. Res. (2007)
- Contribution of sulfate conjugation, deamination, and O-methylation to metabolism of dopamine and norepinephrine in human brain. Rivett, A.J., Eddy, B.J., Roth, J.A. J. Neurochem. (1982)
- Family-based and case-control association studies of catechol-O-methyltransferase in attention deficit hyperactivity disorder suggest genetic sexual dimorphism. Qian, Q., Wang, Y., Zhou, R., Li, J., Wang, B., Glatt, S., Faraone, S.V. Am. J. Med. Genet. B Neuropsychiatr. Genet. (2003)
- Two patients with COMT inhibitor-induced hepatic dysfunction and UGT1A9 genetic polymorphism. Martignoni, E., Cosentino, M., Ferrari, M., Porta, G., Mattarucchi, E., Marino, F., Lecchini, S., Nappi, G. Neurology (2005)
- Down-regulation of caffeic acid o-methyltransferase in maize revisited using a transgenic approach. Piquemal, J., Chamayou, S., Nadaud, I., Beckert, M., Barrière, Y., Mila, I., Lapierre, C., Rigau, J., Puigdomenech, P., Jauneau, A., Digonnet, C., Boudet, A.M., Goffner, D., Pichon, M. Plant Physiol. (2002)
- Catechol-O-methyltransferase in vitiligo. Le Poole, I.C., van den Wijngaard, R.M., Smit, N.P., Oosting, J., Westerhof, W., Pavel, S. Arch. Dermatol. Res. (1994)
- Catechol-o-methyltransferase biochemical genetics: human lymphocyte enzyme. Sladek-Chelgren, S., Weinshilboum, R.M. Biochem. Genet. (1981)
- The COMT L allele modifies the association between MAOB polymorphism and PD in Taiwanese. Wu, R.M., Cheng, C.W., Chen, K.H., Lu, S.L., Shan, D.E., Ho, Y.F., Chern, H.D. Neurology (2001)
- Cytochrome P450 1B1 and catechol-O-methyltransferase polymorphisms and endometrial cancer susceptibility. McGrath, M., Hankinson, S.E., Arbeitman, L., Colditz, G.A., Hunter, D.J., De Vivo, I. Carcinogenesis (2004)
- Epistasis between catechol-O-methyltransferase and type II metabotropic glutamate receptor 3 genes on working memory brain function. Tan, H.Y., Chen, Q., Sust, S., Buckholtz, J.W., Meyers, J.D., Egan, M.F., Mattay, V.S., Meyer-Lindenberg, A., Weinberger, D.R., Callicott, J.H. Proc. Natl. Acad. Sci. U.S.A. (2007)
- An investigation of mammographic density and gene variants in healthy women. Maskarinec, G., Lurie, G., Williams, A.E., Le Marchand, L. Int. J. Cancer (2004)
- Val158Met Polymorphism in catechol-O-methyltransferase gene associated with risk factors for breast cancer. Hong, C.C., Thompson, H.J., Jiang, C., Hammond, G.L., Tritchler, D., Yaffe, M., Boyd, N.F. Cancer Epidemiol. Biomarkers Prev. (2003)