Gene Review:
CR1 - complement component (3b/4b) receptor 1...
Homo sapiens
Synonyms:
C3BR, C3b/C4b receptor, C4BR, CD35, Complement receptor type 1, ...
- Identification of an additional class of C3-binding membrane proteins of human peripheral blood leukocytes and cell lines. Cole, J.L., Housley, G.A., Dykman, T.R., MacDermott, R.P., Atkinson, J.P. Proc. Natl. Acad. Sci. U.S.A. (1985)
- CR1(CD35) and CR2(CD21) complement C3 receptors are expressed on normal human thymocytes and mediate infection of thymocytes with opsonized human immunodeficiency virus. Delibrias, C.C., Mouhoub, A., Fischer, E., Kazatchkine, M.D. Eur. J. Immunol. (1994)
- Structure-activity relationships within the N-terminal short consensus repeats (SCR) of human CR1 (C3b/C4b receptor, CD35): SCR 3 plays a critical role in inhibition of the classical and alternative pathways of complement activation. Mossakowska, D., Dodd, I., Pindar, W., Smith, R.A. Eur. J. Immunol. (1999)
- Ligation of CR1 (C3b receptor, CD35) on CD4+ T lymphocytes enhances viral replication in HIV-infected cells. Mouhoub, A., Delibrias, C.C., Fischer, E., Boyer, V., Kazatchkine, M.D. Clin. Exp. Immunol. (1996)
- Levels of complement regulatory molecules in lung cancer: disappearance of the D17 epitope of CD55 in small-cell carcinoma. Sakuma, T., Kodama, K., Hara, T., Eshita, Y., Shibata, N., Matsumoto, M., Seya, T., Mori, Y. Jpn. J. Cancer Res. (1993)
- A functional single-nucleotide polymorphism in the CR1 promoter region contributes to protection against cerebral malaria. Teeranaipong, P., Ohashi, J., Patarapotikul, J., Kimura, R., Nuchnoi, P., Hananantachai, H., Naka, I., Putaporntip, C., Jongwutiwes, S., Tokunaga, K. J. Infect. Dis. (2008)
- Levels of complement receptor type one (CR1, CD35) on erythrocytes, circulating immune complexes and complement C3 split products C3d and C3c are not changed by short-term physical exercise or training. Thomsen, B.S., Rødgaard, A., Tvede, N., Hansen, F.R., Steensberg, J., Halkjaer Kristensen, J., Pedersen, B.K. International journal of sports medicine. (1992)
- Alterations in trk A, trk B and trk C receptor immunoreactivities in parietal cortex and cerebellum in Alzheimer's disease. Savaskan, E., Müller-Spahn, F., Olivieri, G., Bruttel, S., Otten, U., Rosenberg, C., Hulette, C., Hock, C. Eur. Neurol. (2000)
- Structure of the C3b binding site of CR1 (CD35), the immune adherence receptor. Smith, B.O., Mallin, R.L., Krych-Goldberg, M., Wang, X., Hauhart, R.E., Bromek, K., Uhrin, D., Atkinson, J.P., Barlow, P.N. Cell (2002)
- Complement facilitates early prion pathogenesis. Klein, M.A., Kaeser, P.S., Schwarz, P., Weyd, H., Xenarios, I., Zinkernagel, R.M., Carroll, M.C., Verbeek, J.S., Botto, M., Walport, M.J., Molina, H., Kalinke, U., Acha-Orbea, H., Aguzzi, A. Nat. Med. (2001)
- The chemotactic receptor for human C5a anaphylatoxin. Gerard, N.P., Gerard, C. Nature (1991)
- Isolation of a biologically active macrophage receptor for the third component of complement. Schneider, R.J., Kulczycki, A., Law, S.K., Atkinson, J.P. Nature (1981)
- Association of leukocyte CR1 gene transcription with the disease severity and renal involvement in systemic lupus erythematosus. Verma, J., Arora, V., Marwaha, V., Kumar, A., Das, N. Lupus (2005)
- Systemic lupus erythematosus in three ethnic groups: I. The effects of HLA class II, C4, and CR1 alleles, socioeconomic factors, and ethnicity at disease onset. LUMINA Study Group. Lupus in minority populations, nature versus nurture. Reveille, J.D., Moulds, J.M., Ahn, C., Friedman, A.W., Baethge, B., Roseman, J., Straaton, K.V., Alarcón, G.S. Arthritis Rheum. (1998)
- Defective reticuloendothelial system C3b mediated clearance in rheumatoid arthritis and vasculitis. Cunningham, T.J., Nicholls, K.M., Chen, S.L., Mathews, J.D., Muirden, K.D. J. Rheumatol. (1985)
- Alternating versus concurrent schedules of imatinib and chemotherapy as front-line therapy for Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL). Wassmann, B., Pfeifer, H., Goekbuget, N., Beelen, D.W., Beck, J., Stelljes, M., Bornhäuser, M., Reichle, A., Perz, J., Haas, R., Ganser, A., Schmid, M., Kanz, L., Lenz, G., Kaufmann, M., Binckebanck, A., Brück, P., Reutzel, R., Gschaidmeier, H., Schwartz, S., Hoelzer, D., Ottmann, O.G. Blood (2006)
- Functional differentiation of normal human neutrophils. Glasser, L., Fiederlein, R.L. Blood (1987)
- Complement receptor type 1 (CD35) mediates inhibitory signals in human B lymphocytes. Józsi, M., Prechl, J., Bajtay, Z., Erdei, A. J. Immunol. (2002)
- The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1. Kurtz, C.B., O'Toole, E., Christensen, S.M., Weis, J.H. J. Immunol. (1990)
- Comparative structure and evolution of murine CR2. The homolog of the human C3d/EBV receptor (CD21). Fingeroth, J.D. J. Immunol. (1990)
- The role of complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) in promoting C3 fragment deposition and membrane attack complex formation on normal peripheral human B cells. Nielsen, C.H., Pedersen, M.L., Marquart, H.V., Prodinger, W.M., Leslie, R.G. Eur. J. Immunol. (2002)
- The sequential appearance of Ia-like antigens and two different complement receptors during the maturation of human neutrophils. Ross, G.D., Jarowski, C.I., Rabellino, E.M., Winchester, R.J. J. Exp. Med. (1978)
- Human megakaryocytes. I. Characterization of the membrane and cytoplasmic components of isolated marrow megakaryocytes. Rabellino, E.M., Nachman, R.L., Williams, N., Winchester, R.J., Ross, G.D. J. Exp. Med. (1979)
- Expression, molecular association, and functions of C3 complement receptors CR1 (CD35) and CR2 (CD21) on the human T cell line HPB-ALL. Delibrias, C.C., Fischer, E., Bismuth, G., Kazatchkine, M.D. J. Immunol. (1992)
- Identification and characterization of complement C3 receptors on human astrocytes. Gasque, P., Chan, P., Mauger, C., Schouft, M.T., Singhrao, S., Dierich, M.P., Morgan, B.P., Fontaine, M. J. Immunol. (1996)
- Identification of residues within the 727-767 segment of human complement component C3 important for its interaction with factor H and with complement receptor 1 (CR1, CD35). Oran, A.E., Isenman, D.E. J. Biol. Chem. (1999)
- The C4A and C4B isotypic forms of human complement fragment C4b have the same intrinsic affinity for complement receptor 1 (CR1/CD35). Clemenza, L., Isenman, D.E. J. Immunol. (2004)
- Differential expression of complement proteins and regulatory decay accelerating factor in relation to differentiation of cultured human colon adenocarcinoma cell lines. Bernet-Camard, M.F., Coconnier, M.H., Hudault, S., Servin, A.L. Gut (1996)
- Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes. Leslie, R.G., Prodinger, W.M., Nielsen, C.H. Eur. J. Immunol. (2003)
- Decay-accelerating factor (DAF), complement receptor 1 (CR1), and factor H dissociate the complement AP C3 convertase (C3bBb) via sites on the type A domain of Bb. Hourcade, D.E., Mitchell, L., Kuttner-Kondo, L.A., Atkinson, J.P., Medof, M.E. J. Biol. Chem. (2002)
- Deficiency of an erythrocyte membrane protein with complement regulatory activity in paroxysmal nocturnal hemoglobinuria. Pangburn, M.K., Schreiber, R.D., Müller-Eberhard, H.J. Proc. Natl. Acad. Sci. U.S.A. (1983)
- Quantitative analysis of regions of adenovirus E1A products involved in interactions with cellular proteins. Barbeau, D., Marcellus, R.C., Bacchetti, S., Bayley, S.T., Branton, P.E. Biochem. Cell Biol. (1992)
- Neutrophil elastase cleaves C3bi on opsonized pseudomonas as well as CR1 on neutrophils to create a functionally important opsonin receptor mismatch. Tosi, M.F., Zakem, H., Berger, M. J. Clin. Invest. (1990)
- C3b receptor (CR1) genomic polymorphism in rheumatoid arthritis. Low receptor levels on erythrocytes are an acquired phenomenon. Kumar, A., Malaviya, A.N., Sinha, S., Khandekar, P.S., Banerjee, K., Srivastava, L.M. Immunol. Res. (1994)
- Phagocytosis of Mycobacterium leprae by human monocyte-derived macrophages is mediated by complement receptors CR1 (CD35), CR3 (CD11b/CD18), and CR4 (CD11c/CD18) and IFN-gamma activation inhibits complement receptor function and phagocytosis of this bacterium. Schlesinger, L.S., Horwitz, M.A. J. Immunol. (1991)
- Immunotoxin-mediated inhibition of chronic lymphocytic leukemia cell proliferation in humans. Siena, S., Bregni, M., Formosa, A., Brando, B., Marenco, P., Lappi, D.A., Bonadonna, G., Gianni, A.M. Cancer Res. (1989)
- Characterization of CR1- and membrane cofactor protein-like proteins of two primates. Nickells, M.W., Atkinson, J.P. J. Immunol. (1990)
- Expression and localization of proteins of the complement system in human skin. Dovezenski, N., Billetta, R., Gigli, I. J. Clin. Invest. (1992)
- Identification and characterization of plasma cells in normal human bone marrow by high-resolution flow cytometry. Terstappen, L.W., Johnsen, S., Segers-Nolten, I.M., Loken, M.R. Blood (1990)
- Monoclonal antibodies that recognize lacto-N-fucopentaose III (CD15) react with the adhesion-promoting glycoprotein family (LFA-1/HMac-1/gp 150,95) and CR1 on human neutrophils. Skubitz, K.M., Snook, R.W. J. Immunol. (1987)
- Expression of complement regulator proteins in primary and metastatic malignant melanoma. Weichenthal, M., Siemann, U., Neuber, K., Breitbart, E.W. J. Cutan. Pathol. (1999)
- Improved outcome for high-risk acute myeloid leukemia patients using autologous bone marrow transplantation and monoclonal antibody-purged bone marrow. Selvaggi, K.J., Wilson, J.W., Mills, L.E., Cornwell, G.G., Hurd, D., Dodge, W., Gingrich, R., Martin, S.E., McMillan, R., Miller, W. Blood (1994)
- Complement receptors on Raji cells. The presence of a new type of C3 receptor. Okuda, T., Tachibana, T. Immunology (1980)
- Expression of complement regulatory proteins CR1, DAF, MCP and CD59 in haematological malignancies. Guc, D., Canpinar, H., Kucukaksu, C., Kansu, E. Eur. J. Haematol. (2000)