Disease relevance of Smc2

• Low-titered viremia followed by development of antibody was observed in scrub hares (Lepus saxatilis), Cape ground squirrels (Xerus inauris), red veld rats (Aethomys chrysophilus), white tailed rats (Mystromys albicaudatus), bushveld gerbils (Tatera leucogaster), striped mice (Rhabdomys pumilio), and guinea pigs [1].
• Ticks and antibodies to Borrelia burgdorferi from mammals at Cape Hatteras, NC and Assateague Island, MD and VA [2].
• Serological investigations in Q-fever and listeriosis of wild-living small mammals on the Cape Verde Islands [3].
• Cyanobacterial (blue-green algae) poisoning of livestock in the western Cape Province of South Africa [4].
• Serological investigations of small mammals had been made on the Island Santiago (Cape Verde Islands), to clear up how far synantropic, small mammals are reservoir hosts for pathogens, such as Coxiella burnetti and Listeria monocytogenes [3].

High impact information on Smc2

• A new diglucoside having a 5-methylchromone moiety was isolated from a commercial sample of Cape aloe, the dried exudate from Aloe ferox Miller, and named aloeresin I [5].
• Aloeresin I (1) (1 micromol/cm2) reduces in vivo the oedematous response (39 %) induced by Croton oil in the mouse ear with the same potency as aloesin, one of the most abundant Cape aloe constituents, and to a higher extent than aloeresin H (2) [5].
• Crocetin is a carotenoid isolated from the seeds of Cape jasmine (Gardenia jasminoides) [6].
• In November 1984 a case of Crimean-Congo haemorrhagic fever (CCHF) occurred in a worker who became ill after slaughtering ostriches (Struthio camelus) on a farm near Oudtshoorn in the Cape province of South Africa. The diagnosis was confirmed by isolation of CCHF virus from the patient's serum and by demonstration of a specific antibody response [7].
• Nine strains of Avalon virus were isolated from Ixodes uriae ticks collected in the Cape Sizun seabird reserve, Brittany, from 1979 to 1985, during a longitudinal study of consequences of tick-borne infections for kittiwakes (Rissa tridactyla) [8].

References