Gene Review:
Fut7 - fucosyltransferase 7
Mus musculus
Synonyms:
AI853193, Alpha-(1,3)-fucosyltransferase 7, FTVII, Fuc-TVII, FucT-VII, ...
- L-selectin facilitation of metastasis involves temporal induction of Fut7-dependent ligands at sites of tumor cell arrest. Läubli, H., Stevenson, J.L., Varki, A., Varki, N.M., Borsig, L. Cancer Res. (2006)
- Fuc-TVII is required for T helper 1 and T cytotoxic 1 lymphocyte selectin ligand expression and recruitment in inflammation, and together with Fuc-TIV regulates naive T cell trafficking to lymph nodes. Smithson, G., Rogers, C.E., Smith, P.L., Scheidegger, E.P., Petryniak, B., Myers, J.T., Kim, D.S., Homeister, J.W., Lowe, J.B. J. Exp. Med. (2001)
- Abrogation of functional selectin-ligand expression reduces migration of pathogenic CD8+ T cells into heart. Cai, Y.H., Alvarez, A., Alcaide, P., Duramad, P., Lim, Y.C., Jarolim, P., Lowe, J.B., Luscinskas, F.W., Lichtman, A.H. J. Immunol. (2006)
- Alpha(1,3)fucosyltransferases FucT-IV and FucT-VII control susceptibility to atherosclerosis in apolipoprotein E-/- mice. Homeister, J.W., Daugherty, A., Lowe, J.B. Arterioscler. Thromb. Vasc. Biol. (2004)
- Alpha(1,3)-fucosyltransferase VII and alpha(2,3)-sialyltransferase IV are up-regulated in activated CD4 T cells and maintained after their differentiation into Th1 and migration into inflammatory sites. Blander, J.M., Visintin, I., Janeway, C.A., Medzhitov, R. J. Immunol. (1999)
- The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Malý, P., Thall, A., Petryniak, B., Rogers, C.E., Smith, P.L., Marks, R.M., Kelly, R.J., Gersten, K.M., Cheng, G., Saunders, T.L., Camper, S.A., Camphausen, R.T., Sullivan, F.X., Isogai, Y., Hindsgaul, O., von Andrian, U.H., Lowe, J.B. Cell (1996)
- The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing. Homeister, J.W., Thall, A.D., Petryniak, B., Malý, P., Rogers, C.E., Smith, P.L., Kelly, R.J., Gersten, K.M., Askari, S.W., Cheng, G., Smithson, G., Marks, R.M., Misra, A.K., Hindsgaul, O., von Andrian, U.H., Lowe, J.B. Immunity (2001)
- Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels. Weninger, W., Ulfman, L.H., Cheng, G., Souchkova, N., Quackenbush, E.J., Lowe, J.B., von Andrian, U.H. Immunity (2000)
- Expression cloning and characterization of a novel murine alpha1, 3-fucosyltransferase, mFuc-TIX, that synthesizes the Lewis x (CD15) epitope in brain and kidney. Kudo, T., Ikehara, Y., Togayachi, A., Kaneko, M., Hiraga, T., Sasaki, K., Narimatsu, H. J. Biol. Chem. (1998)
- Cutting edge: differential requirements for Stat4 in expression of glycosyltransferases responsible for selectin ligand formation in Th1 cells. White, S.J., Underhill, G.H., Kaplan, M.H., Kansas, G.S. J. Immunol. (2001)
- Intercellular cell adhesion molecule-1 and selectin ligands in acute cardiac allograft rejection: a study on gene-deficient mouse models. Lácha, J., Bushell, A., Smetana, K., Rossmann, P., Pribylová, P., Wood, K., Malý, P. J. Leukoc. Biol. (2002)
- Overexpression of alpha(1,3)-fucosyltransferase VII is sufficient for the acquisition of lung colonization phenotype in human lung adenocarcinoma HAL-24Luc cells. Martín-Satué, M., de Castellarnau, C., Blanco, J. Br. J. Cancer (1999)
- Pathophysiological contributions of fucosyltransferases in renal ischemia reperfusion injury. Burne, M.J., Rabb, H. J. Immunol. (2002)
- Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant. Natsuka, S., Gersten, K.M., Zenita, K., Kannagi, R., Lowe, J.B. J. Biol. Chem. (1994)
- Efficient recruitment of lymphocytes in inflamed brain venules requires expression of cutaneous lymphocyte antigen and fucosyltransferase-VII. Piccio, L., Rossi, B., Colantonio, L., Grenningloh, R., Gho, A., Ottoboni, L., Homeister, J.W., Scarpini, E., Martinello, M., Laudanna, C., D'Ambrosio, D., Lowe, J.B., Constantin, G. J. Immunol. (2005)
- Alpha(1,3)-fucosyltransferase VII-dependent synthesis of P- and E-selectin ligands on cultured T lymphoblasts. Knibbs, R.N., Craig, R.A., Mály, P., Smith, P.L., Wolber, F.M., Faulkner, N.E., Lowe, J.B., Stoolman, L.M. J. Immunol. (1998)
- P-selectin glycoprotein ligand-1 and E-selectin ligand-1 are differentially modified by fucosyltransferases Fuc-TIV and Fuc-TVII in mouse neutrophils. Huang, M.C., Zöllner, O., Moll, T., Maly, P., Thall, A.D., Lowe, J.B., Vestweber, D. J. Biol. Chem. (2000)
- Increased expression of alpha(1,3)-fucosyltransferase-VII and P-selectin binding of synovial fluid T cells in juvenile idiopathic arthritis. De Benedetti, F., Pignatti, P., Biffi, M., Bono, E., Wahid, S., Ingegnoli, F., Chang, S.Y., Alexander, H., Massa, M., Pistorio, A., Martini, A., Pitzalis, C., Sinigaglia, F., Rogge, L. J. Rheumatol. (2003)
- Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice. Beck, P.L., Xavier, R., Lu, N., Nanda, N.N., Dinauer, M., Podolsky, D.K., Seed, B. Gastroenterology (2000)