Gene Review:
Grid2 - glutamate receptor, ionotropic, delta 2
Mus musculus
Synonyms:
B230104L07Rik, GluD2, GluR delta-2 subunit, GluRdelta2, Glutamate receptor ionotropic, delta-2, ...
- C-met activation is necessary but not sufficient for liver colonization by B16 murine melanoma cells. Lin, S., Rusciano, D., Lorenzoni, P., Hartmann, G., Birchmeier, W., Giordano, S., Comoglio, P., Burger, M.M. Clin. Exp. Metastasis (1998)
- GluR delta 2 and the development and death of cerebellar Purkinje neurons in lurcher mice. Heintz, N., De Jager, P.L. Ann. N. Y. Acad. Sci. (1999)
- Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors. Liang, T.J., Reid, A.E., Xavier, R., Cardiff, R.D., Wang, T.C. J. Clin. Invest. (1996)
- Timed active avoidance learning in lurcher mutant mice. Monfort, V., Chapillon, P., Mellier, D., Lalonde, R., Caston, J. Behav. Brain Res. (1998)
- Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice. Kashiwabuchi, N., Ikeda, K., Araki, K., Hirano, T., Shibuki, K., Takayama, C., Inoue, Y., Kutsuwada, T., Yagi, T., Kang, Y. Cell (1995)
- New role of delta2-glutamate receptors in AMPA receptor trafficking and cerebellar function. Hirai, H., Launey, T., Mikawa, S., Torashima, T., Yanagihara, D., Kasaura, T., Miyamoto, A., Yuzaki, M. Nat. Neurosci. (2003)
- Lurcher GRID2-induced death and depolarization can be dissociated in cerebellar Purkinje cells. Selimi, F., Lohof, A.M., Heitz, S., Lalouette, A., Jarvis, C.I., Bailly, Y., Mariani, J. Neuron (2003)
- A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice. Yue, Z., Horton, A., Bravin, M., DeJager, P.L., Selimi, F., Heintz, N. Neuron (2002)
- A hot spot for hotfoot mutations in the gene encoding the delta2 glutamate receptor. Wang, Y., Matsuda, S., Drews, V., Torashima, T., Meisler, M.H., Yuzaki, M. Eur. J. Neurosci. (2003)
- The human glutamate receptor delta 2 gene (GRID2) maps to chromosome 4q22. Hu, W., Zuo, J., De Jager, P.L., Heintz, N. Genomics (1998)
- Cytochrome oxidase activity is increased in +/Lc Purkinje cells destined to die. Vogel, M.W., Fan, H., Sydnor, J., Guidetti, P. Neuroreport (2001)
- The C-terminal juxtamembrane region of the delta 2 glutamate receptor controls its export from the endoplasmic reticulum. Matsuda, S., Hannen, R., Matsuda, K., Yamada, N., Tubbs, T., Yuzaki, M. Eur. J. Neurosci. (2004)
- The Lurcher mutation of an alpha-amino-3-hydroxy-5-methyl- 4-isoxazolepropionic acid receptor subunit enhances potency of glutamate and converts an antagonist to an agonist. Taverna, F., Xiong, Z.G., Brandes, L., Roder, J.C., Salter, M.W., MacDonald, J.F. J. Biol. Chem. (2000)
- Survival of interneurons and parallel fiber synapses in a cerebellar cortex deprived of Purkinje cells: studies in the double mutant mouse Grid2Lc/+;Bax(-/-). Zanjani, S.H., Selimi, F., Vogel, M.W., Haeberlé, A.M., Boeuf, J., Mariani, J., Bailly, Y.J. J. Comp. Neurol. (2006)
- Altered intracellular localization of the glutamate receptor channel delta 2 subunit in weaver and reeler Purkinje cells. Takayama, C., Nakagawa, S., Watanabe, M., Kurihara, H., Mishina, M., Inoue, Y. Brain Res. (1997)
- Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor delta 2 subunit. Miyagi, Y., Yamashita, T., Fukaya, M., Sonoda, T., Okuno, T., Yamada, K., Watanabe, M., Nagashima, Y., Aoki, I., Okuda, K., Mishina, M., Kawamoto, S. J. Neurosci. (2002)
- Developmental changes in expression and distribution of the glutamate receptor channel delta 2 subunit according to the Purkinje cell maturation. Takayama, C., Nakagawa, S., Watanabe, M., Mishina, M., Inoue, Y. Brain Res. Dev. Brain Res. (1996)
- Bax inactivation in lurcher mutants rescues cerebellar granule cells but not purkinje cells or inferior olivary neurons. Selimi, F., Vogel, M.W., Mariani, J. J. Neurosci. (2000)
- Roles of glutamate receptor delta 2 subunit (GluRdelta 2) and metabotropic glutamate receptor subtype 1 (mGluR1) in climbing fiber synapse elimination during postnatal cerebellar development. Hashimoto, K., Ichikawa, R., Takechi, H., Inoue, Y., Aiba, A., Sakimura, K., Mishina, M., Hashikawa, T., Konnerth, A., Watanabe, M., Kano, M. J. Neurosci. (2001)
- The protein-tyrosine phosphatase PTPMEG interacts with glutamate receptor delta 2 and epsilon subunits. Hironaka, K., Umemori, H., Tezuka, T., Mishina, M., Yamamoto, T. J. Biol. Chem. (2000)
- Rescue of abnormal phenotypes of the delta2 glutamate receptor-null mice by mutant delta2 transgenes. Hirai, H., Miyazaki, T., Kakegawa, W., Matsuda, S., Mishina, M., Watanabe, M., Yuzaki, M. EMBO Rep. (2005)
- Heteromer formation of delta2 glutamate receptors with AMPA or kainate receptors. Kohda, K., Kamiya, Y., Matsuda, S., Kato, K., Umemori, H., Yuzaki, M. Brain Res. Mol. Brain Res. (2003)
- Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells. Uemura, T., Mori, H., Mishina, M. Mol. Cell. Neurosci. (2004)
- The delta2 glutamate receptor: 10 years later. Yuzaki, M. Neurosci. Res. (2003)
- Identification and characterization of a novel Delphilin variant with an alternative N-terminus. Yamashita, T., Miyagi, Y., Ono, M., Ito, H., Watanabe, K., Sonoda, T., Tsuzuki, K., Ozawa, S., Aoki, I., Okuda, K., Mishina, M., Kawamoto, S. Brain Res. Mol. Brain Res. (2005)
- Control of synaptic connection by glutamate receptor delta2 in the adult cerebellum. Takeuchi, T., Miyazaki, T., Watanabe, M., Mori, H., Sakimura, K., Mishina, M. J. Neurosci. (2005)
- Characterization of hippocampal theta rhythm in wild-type mice and glutamate receptor subunit delta2 mutant mice during eyeblink conditioning with a short trace interval. Takatsuki, K., Kawahara, S., Mishina, M., Kirino, Y. Brain Res. (2005)
- Roles of diverse glutamate receptors in brain functions elucidated by subunit-specific and region-specific gene targeting. Mori, H., Mishina, M. Life Sci. (2003)
- Membrane-proximal region of glutamate receptor delta2 subunit is critical for long-term depression and interaction with protein interacting with C kinase 1 in a cerebellar Purkinje neuron. Yawata, S., Tsuchida, H., Kengaku, M., Hirano, T. J. Neurosci. (2006)
- Spectrin mutations cause spinocerebellar ataxia type 5. Ikeda, Y., Dick, K.A., Weatherspoon, M.R., Gincel, D., Armbrust, K.R., Dalton, J.C., Stevanin, G., Dürr, A., Zühlke, C., Bürk, K., Clark, H.B., Brice, A., Rothstein, J.D., Schut, L.J., Day, J.W., Ranum, L.P. Nat. Genet. (2006)