Gene Review:
Hba-a1 - hemoglobin alpha, adult chain 1
Mus musculus
Synonyms:
Alpha-globin, Hba, Hba1, Hbat1, Hemoglobin alpha chain, ...
- MRG15 regulates embryonic development and cell proliferation. Tominaga, K., Kirtane, B., Jackson, J.G., Ikeno, Y., Ikeda, T., Hawks, C., Smith, J.R., Matzuk, M.M., Pereira-Smith, O.M. Mol. Cell. Biol. (2005)
- Lethal alpha-thalassaemia created by gene targeting in mice and its genetic rescue. Pászty, C., Mohandas, N., Stevens, M.E., Loring, J.F., Liebhaber, S.A., Brion, C.M., Rubin, E.M. Nat. Genet. (1995)
- Inactivation of mouse alpha-globin gene by homologous recombination: mouse model of hemoglobin H disease. Chang, J., Lu, R.H., Xu, S.M., Meneses, J., Chan, K., Pedersen, R., Kan, Y.W. Blood (1996)
- Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells. Imren, S., Payen, E., Westerman, K.A., Pawliuk, R., Fabry, M.E., Eaves, C.J., Cavilla, B., Wadsworth, L.D., Beuzard, Y., Bouhassira, E.E., Russell, R., London, I.M., Nagel, R.L., Leboulch, P., Humphries, R.K. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Improvement of erythropoiesis in beta-thalassemic mice by continuous erythropoietin delivery from muscle. Bohl, D., Bosch, A., Cardona, A., Salvetti, A., Heard, J.M. Blood (2000)
- Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease. Tufarelli, C., Stanley, J.A., Garrick, D., Sharpe, J.A., Ayyub, H., Wood, W.G., Higgs, D.R. Nat. Genet. (2003)
- Changes in gene position are accompanied by a change in time of replication. Calza, R.E., Eckhardt, L.A., DelGiudice, T., Schildkraut, C.L. Cell (1984)
- Secondary structure of mouse and rabbit alpha- and beta-globin mRNAs: differential accessibility of alpha and beta initiator AUG codons towards nucleases. Pavlakis, G.N., Lockard, R.E., Vamvakopoulos, N., Rieser, L., RajBhandary, U.L., Vournakis, J.N. Cell (1980)
- The structure of a human alpha-globin pseudogene and its relationship to alpha-globin gene duplication. Proudfoot, N.J., Maniatis, T. Cell (1980)
- The LCR-like alpha-globin positive regulatory element functions as an enhancer in transiently transfected cells during erythroid differentiation. Pondel, M.D., George, M., Proudfoot, N.J. Nucleic Acids Res. (1992)
- Regulated expression of the c-myb and c-myc oncogenes during erythroid differentiation. Kirsch, I.R., Bertness, V., Silver, J., Hollis, G.F. J. Cell. Biochem. (1986)
- Expression profiling and gene discovery in the mouse lens. Wride, M.A., Mansergh, F.C., Adams, S., Everitt, R., Minnema, S.E., Rancourt, D.E., Evans, M.J. Mol. Vis. (2003)
- Localization and characterization of the mouse alpha-globin locus control region. Kielman, M.F., Smits, R., Bernini, L.F. Genomics (1994)
- Cloning and characterization of the mouse alpha globin cluster and a new hypervariable marker. Zhao, Q.Z., Liang, X.L., Mitra, S., Gourdon, G., Alter, B.P. Mamm. Genome (1996)
- Regulation of murine alpha-, beta major-, and beta minor-globin gene expression. Weich, N., Marks, P.A., Rifkind, R.A. Biochem. Biophys. Res. Commun. (1988)
- Sp1 functions in a chromatin-dependent manner to augment human alpha-globin promoter activity. Pondel, M.D., Murphy, S., Pearson, L., Craddock, C., Proudfoot, N.J. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Human embryonic zeta-globin gene expression in mouse-human hybrid erythroid cell lines. Luo, H.Y., Deisseroth, A.B., Chui, D.H. Blood (1995)
- Erythroid cell-specific determinants of alpha-globin mRNA stability. Weiss, I.M., Liebhaber, S.A. Mol. Cell. Biol. (1994)
- Compensatory increase in levels of beta minor globin in murine beta-thalassemia is under translational control. Curcio, M.J., Kantoff, P., Schafer, M.P., Anderson, W.F., Safer, B. J. Biol. Chem. (1986)
- A C3H strain-specific allele (alpha va126) of the murine alpha-globin gene newly detected by UT-PAGE and RT-PCR-SSCP analysis. Sato, H., Nagayoshi, M., Ikawa, Y., Kato, M.V. Mutat. Res. (1996)
- The primary structure of genetic variants of mouse hemoglobin. Popp, R.A., Bailiff, E.G., Skow, L.C., Whitney, J.B. Biochem. Genet. (1982)
- Unusual DNA binding characteristics of an in vitro translation product of the CCAAT binding protein mYB-1. Gai, X.X., Lipson, K.E., Prystowsky, M.B. Nucleic Acids Res. (1992)
- Heme-dependent up-regulation of the alpha-globin gene expression by transcriptional repressor Bach1 in erythroid cells. Tahara, T., Sun, J., Igarashi, K., Taketani, S. Biochem. Biophys. Res. Commun. (2004)
- Role of AP1/NFE2 binding sites in endogenous alpha-globin gene transcription. Loyd, M.R., Okamoto, Y., Randall, M.S., Ney, P.A. Blood (2003)
- Characterization and comparison of the human and mouse Dist1/alpha-globin complex reveals a tightly packed multiple gene cluster containing differentially expressed transcription units. Kielman, M.F., Smits, R., Hof, I., Bernini, L.F. Genomics (1996)
- CP2 binding to the promoter is essential for the enhanced transcription of globin genes in erythroid cells. Chae, J.H., Kim, C.G. Mol. Cells (2003)
- In vivo association of the stability control protein alphaCP with actively translating mRNAs. Ji, X., Kong, J., Liebhaber, S.A. Mol. Cell. Biol. (2003)
- Removal of an mRNA destabilizing element correlates with the increased oncogenicity of proto-oncogene fos. Raymond, V., Atwater, J.A., Verma, I.M. Oncogene Res. (1989)
- Mouse zeta- and alpha-globin genes: embryonic survival, alpha-thalassemia, and genetic background effects. Leder, A., Daugherty, C., Whitney, B., Leder, P. Blood (1997)
- CACCC and GATA-1 sequences make the constitutively expressed alpha-globin gene erythroid-responsive in mouse erythroleukemia cells. Ren, S., Li, J., Atweh, G.F. Nucleic Acids Res. (1996)
- Upregulation of alpha globin promotes apoptotic cell death in the hematopoietic cell line FL5.12. Brecht, K., Simonen, M., Heim, J. Apoptosis (2005)
- Identification of an erythroid-enriched endoribonuclease activity involved in specific mRNA cleavage. Wang, Z., Kiledjian, M. EMBO J. (2000)
- Physical characterization of the purified CCAAT transcription factor, alpha-CP1. Kim, C.G., Sheffery, M. J. Biol. Chem. (1990)
- Properties of the mouse alpha-globin HS-26: relationship to HS-40, the major enhancer of human alpha-globin gene expression. Bouhassira, E.E., Kielman, M.F., Gilman, J., Fabry, M.F., Suzuka, S., Leone, O., Gikas, E., Bernini, L.F., Nagel, R.L. Am. J. Hematol. (1997)
- Chromatin-binding in vivo of the erythroid kruppel-like factor, EKLF, in the murine globin loci. Shyu, Y.C., Wen, S.C., Lee, T.L., Chen, X., Hsu, C.T., Chen, H., Chen, R.L., Hwang, J.L., Shen, C.K. Cell Res. (2006)
- Transcription factor CP2 is crucial in hemoglobin synthesis during erythroid terminal differentiation in vitro. Chae, J.H., Lee, Y.H., Kim, C.G. Biochem. Biophys. Res. Commun. (1999)
- Comparison of cloned mouse alpha- and beta-globin genes: conservation of intervening sequence locations and extragenic homology. Leder, A., Miller, H.I., Hamer, D.H., Seidman, J.G., Norman, B., Sullivan, M., Leder, P. Proc. Natl. Acad. Sci. U.S.A. (1978)
- Developmental analysis of the Hba(th-J) mouse mutation: effects on mouse peri-implantation development and identification of two candidate genes. Hendrey, J., Lin, D., Dziadek, M. Dev. Biol. (1995)